Publications by authors named "Justin R Hamilton"

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Growth factor independent 1B is a metabolic regulator that exerts pleiotropic effects on platelet function.
Marie-Christine Morel-Kopp, Marie Levade, Lucinda Beutler, Qiang Chen, Jad Othman, Justin R Hamilton

J Thromb Haemost· October 2025

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Confining thrombus morphospace through targeted inhibition of platelet mechanosensory signaling.
Pia Larsson, Abigail McGovern, Volga Tarlac, Natasha M Setiabakti, Louis Parker, Justin R Hamilton

J Thromb Haemost· September 2025

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Finding and following: a deep learning-based pipeline for tracking platelets during thrombus formation and .
Abigail S McGovern, Pia Larsson, Volga Tarlac, Natasha Setiabakti, Leila Shabani Mashcool, Justin R Hamilton

Platelets· December 2024

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Megakaryocytes possess a STING pathway that is transferred to platelets to potentiate activation.
Firas El-Mortada, Karima Landelouci, Samuel Bertrand-Perron, Félix-Antoine Aubé, Amélie Poirier, Justin R Hamilton

Life Sci Alliance· February 2024

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PI3KC2α inhibition is antithrombotic in blood from hypercholesterolemic mice.
Natasha M Setiabakti, Volga Tarlac, Pia Larsson, Justin R Hamilton

J Thromb Haemost· January 2024

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A microfluidic method to investigate platelet mechanotransduction under extensional strain.
Nurul A Zainal Abidin, Mariia Timofeeva, Crispin Szydzik, Farzan Akbaridoust, Chitrarth Lav, Justin R Hamilton

Res Pract Thromb Haemost· January 2023

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Identification of a Distinct Platelet Phenotype in the Elderly: ADP Hypersensitivity Coexists With Platelet PAR (Protease-Activated Receptor)-1 and PAR-4-Mediated Thrombin Resistance.
Sonali R Gnanenthiran, Gabrielle J Pennings, Caroline J Reddel, Heather Campbell, Maaike Kockx, Justin R Hamilton

Arterioscler Thromb Vasc Biol· August 2022

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The PAR4 Platelet Thrombin Receptor Variant rs773902 does not Impact the Incidence of Thrombotic or Bleeding Events in a Healthy Older Population.
Maria V Selvadurai, Moeen Riaz, Sophia Xie, Andrew M Tonkin, John J McNeil, Justin R Hamilton

Thromb Haemost· July 2022

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Neutrophil cathepsin G proteolysis of protease-activated receptor 4 generates a novel, functional tethered ligand.
Michelle L Stoller, Indranil Basak, Frederik Denorme, Jesse W Rowley, James Alsobrooks, Justin R Hamilton

Blood Adv· April 2022

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Phosphoinositide 3-Kinases as Potential Targets for Thrombosis Prevention.
Natasha M Setiabakti, Pia Larsson, Justin R Hamilton

Int J Mol Sci· April 2022

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An extensional strain sensing mechanosome drives adhesion-independent platelet activation at supraphysiological hemodynamic gradients.
Nurul A Zainal Abidin, Eric K W Poon, Crispin Szydzik, Mariia Timofeeva, Farzan Akbaridoust, Justin R Hamilton

BMC Biol· March 2022

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Ionotropic glutamate receptors in platelets: opposing effects and a unifying hypothesis.
Maggie L Kalev-Zylinska, Marie-Christine Morel-Kopp, Christopher M Ward, James I Hearn, Justin R Hamilton

Platelets· November 2021

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Determination of PAR4 numbers on the surface of human platelets: no effect of the single nucleotide polymorphism rs773902.
Simeng Li, Volga Tarlac, Roberto B I Christanto, Shauna L French, Justin R Hamilton

Platelets· October 2021

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Analysis of the (PAR4) Single Nucleotide Polymorphism () in an Indigenous Australian Population.
Dian Ningtyas, Russell J Thomson, Volga Tarlac, Shivashankar H Nagaraj, Wendy Hoy, Justin R Hamilton

Front Genet· April 2020

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Using PAR4 Inhibition as an Anti-Thrombotic Approach: Why, How, and When?
Simeng Li, Volga Tarlac, Justin R Hamilton

Int J Mol Sci· November 2019

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Shared roles for and in murine platelet production and function.
Sung K Chiu, Stephanie L Orive, Mitchell J Moon, Jesslyn Saw, Sarah Ellis, Justin R Hamilton

Blood· September 2019

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Active Micropump-Mixer for Rapid Antiplatelet Drug Screening in Whole Blood.
Crispin Szydzik, Rose J Brazilek, Farzan Akbaridoust, Charitha de Silva, Mitchell Moon, Justin R Hamilton

Anal Chem· August 2019

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The mode of anesthesia influences outcome in mouse models of arterial thrombosis.
Maithili Sashindranath, Sharelle A Sturgeon, Shauna French, Daphne D D Craenmehr, Carly Selan, Justin R Hamilton

Res Pract Thromb Haemost· April 2019

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The PI 3-kinase PI3KC2α regulates mouse platelet membrane structure and function independently of membrane lipid composition.
Maria V Selvadurai, Rose J Brazilek, Mitchell J Moon, Jean-Yves Rinckel, Anita Eckly, Justin R Hamilton

FEBS Lett· January 2019

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Structure and function of the open canalicular system - the platelet's specialized internal membrane network.
Maria V Selvadurai, Justin R Hamilton

Platelets· June 2018

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A function-blocking PAR4 antibody is markedly antithrombotic in the face of a hyperreactive PAR4 variant.
Shauna L French, Claudia Thalmann, Paul F Bray, Lynn E Macdonald, Andrew J Murphy, Justin R Hamilton

Blood Adv· June 2018

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Perinatal lethality of Par4 mice delivered by primiparous dams reveals spontaneous bleeding in mice without platelet thrombin receptor function.
Shauna L French, Justin R Hamilton

Platelets· March 2018

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Inhibition of NMDA receptor function with an anti-GluN1-S2 antibody impairs human platelet function and thrombosis.
Taryn N Green, Justin R Hamilton, Marie-Christine Morel-Kopp, Zhaohua Zheng, Ting-Yu T Chen

Platelets· December 2017

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Drugs targeting protease-activated receptor-4 improve the anti-thrombotic therapeutic window.
Shauna L French, Justin R Hamilton

Ann Transl Med· December 2017

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