Publications by authors named "Jyothi Parvathareddy"

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Efficacy of a brain-penetrant antiviral in lethal Venezuelan and eastern equine encephalitis mouse models.
Xufeng Cao, Dong Yang, Jyothi Parvathareddy, Yong-Kyu Chu, Eun Jung Kim

Sci Transl Med· April 2023

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Upper Respiratory Infection Drives Clinical Signs and Inflammatory Responses Following Heterologous Challenge of SARS-CoV-2 Variants of Concern in K18 Mice.
Jacob H Nichols, Evan P Williams, Jyothi Parvathareddy, Xueyuan Cao, Ying Kong

Viruses· April 2023

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AI-Accelerated Design of Targeted Covalent Inhibitors for SARS-CoV-2.
Rajendra P Joshi, Katherine J Schultz, Jesse William Wilson, Agustin Kruel, Rohith Anand Varikoti, Jyothi Parvathareddy

J Chem Inf Model· March 2023

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Potent and selective covalent inhibition of the papain-like protease from SARS-CoV-2.
Brian C Sanders, Suman Pokhrel, Audrey D Labbe, Irimpan I Mathews, Connor J Cooper, Jyothi Parvathareddy

Nat Commun· March 2023

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Dissecting Phenotype from Genotype with Clinical Isolates of SARS-CoV-2 First Wave Variants.
Mariah K Taylor, Evan P Williams, Yi Xue, Piroon Jenjaroenpun, Thidathip Wongsurawat, Jyothi Parvathareddy

Viruses· February 2023

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Potent and Selective Covalent Inhibition of the Papain-like Protease from SARS-CoV-2.
Brian Sanders, Suman Pokhrel, Audrey Labbe, Irimpan Mathews, Connor Cooper, Jyothi Parvathareddy

Res Sq· July 2022

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Potent and Selective Covalent Inhibition of the Papain-like Protease from SARS-CoV-2.
Brian Sanders, Suman Pokhrel, Audrey Labbe, Irimpan Mathews, Connor Cooper, Jyothi Parvathareddy

Res Sq· July 2022

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Cardiopulmonary Injury in the Syrian Hamster Model of COVID-19.
Yi Xue, Dong Yang, Peter Vogel, Jennifer Stabenow, Lillian Zalduondo, Jyothi Parvathareddy

Viruses· June 2022

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Covalent narlaprevir- and boceprevir-derived hybrid inhibitors of SARS-CoV-2 main protease.
Daniel W Kneller, Hui Li, Gwyndalyn Phillips, Kevin L Weiss, Qiu Zhang, Jyothi Parvathareddy

Nat Commun· April 2022

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Covalent narlaprevir- and boceprevir-derived hybrid inhibitors of SARS-CoV-2 main protease: room-temperature X-ray and neutron crystallography, binding thermodynamics, and antiviral activity.
Daniel Kneller, Hui Li, Gwyndalyn Phillips, Kevin Weiss, Qiu Zhang, Jyothi Parvathareddy

Res Sq· February 2022

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Drug Repurposing to Identify Nilotinib as a Potential SARS-CoV-2 Main Protease Inhibitor: Insights from a Computational and Study.
Souvik Banerjee, Shalini Yadav, Sourav Banerjee, Sayo O Fakayode, Jyothi Parvathareddy

J Chem Inf Model· November 2021

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Virtual and Antiviral Screening Revive Therapeutic Drugs for COVID-19.
Giovanni Bocci, Steven B Bradfute, Chunyan Ye, Matthew J Garcia, Jyothi Parvathareddy

ACS Pharmacol Transl Sci· December 2020

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Emergence and Magnitude of ML336 Resistance in Venezuelan Equine Encephalitis Virus Depend on the Microenvironment.
Jasper Lee, Jyothi Parvathareddy, Dong Yang, Shruti Bansal, Kathryn O'Connell

J Virol· October 2020

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Rapid Sequencing of Multiple RNA Viruses in Their Native Form.
Thidathip Wongsurawat, Piroon Jenjaroenpun, Mariah K Taylor, Jasper Lee, Aline Lavado Tolardo, Jyothi Parvathareddy

Front Microbiol· February 2019

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Exposure to environmentally persistent free radicals during gestation lowers energy expenditure and impairs skeletal muscle mitochondrial function in adult mice.
Erin J Stephenson, Alyse Ragauskas, Sridhar Jaligama, JeAnna R Redd, Jyothi Parvathareddy

Am J Physiol Endocrinol Metab· June 2016

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Genetic control of weight loss during pneumonic Burkholderia pseudomallei infection.
Felicia D Emery, Jyothi Parvathareddy, Ashutosh K Pandey, Yan Cui, Robert W Williams

Pathog Dis· July 2014

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NaxD is a deacetylase required for lipid A modification and Francisella pathogenesis.
Anna C Llewellyn, Jinshi Zhao, Feng Song, Jyothi Parvathareddy, Qian Xu

Mol Microbiol· November 2012

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Visualization of murine intranasal dosing efficiency using luminescent Francisella tularensis: effect of instillation volume and form of anesthesia.
Mark A Miller, Jennifer M Stabenow, Jyothi Parvathareddy, Andrew J Wodowski, Thomas P Fabrizio

PLoS One· August 2012

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A galU mutant of Francisella tularensis is attenuated for virulence in a murine pulmonary model of tularemia.
Himangi R Jayakar, Jyothi Parvathareddy, Elizabeth A Fitzpatrick, Xiaowen R Bina, James E Bina

BMC Microbiol· August 2011

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