Publications by authors named "K-Raman Purushothaman"

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First-in-kind 3D bioprinted human skin model using recombinant human collagen.
Hemanth Gudapati, Rafaela Mayumi Simoes Torigoe, Aydin Tahmasebifar, K-Raman Purushothaman, Saranya Wyles

Arch Dermatol Res· April 2025

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Clearance of p21 highly expressing senescent cells accelerates cutaneous wound healing.
Nathan S Gasek, Pengyi Yan, Junyu Zhu, K-Raman Purushothaman, Taewan Kim

Nat Aging· January 2025

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Histological features of restenosis associated with paclitaxel drug-coated balloon: implications for therapy.
Prakash Krishnan, K-Raman Purushothaman, Meerarani Purushothaman, Arthur Tarricone, Simon Chen

Cardiovasc Pathol· February 2020

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Incremental effects of diabetes mellitus and chronic kidney disease in medial arterial calcification: Synergistic pathways for peripheral artery disease progression.
Prakash Krishnan, Pedro R Moreno, Irene C Turnbull, Meerarani Purushothaman, Urooj Zafar, K-Raman Purushothaman

Vasc Med· October 2019

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Association of altered collagen content and lysyl oxidase expression in degenerative mitral valve disease.
K-Raman Purushothaman, Meerarani Purushothaman, Irene C Turnbull, David H Adams, Anelechi Anyanwu

Cardiovasc Pathol· August 2018

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Combined PET/DCE-MRI in a Rabbit Model of Atherosclerosis: Integrated Quantification of Plaque Inflammation, Permeability, and Burden During Treatment With a Leukotriene A4 Hydrolase Inhibitor.
Claudia Calcagno, Olivier Lairez, Julie Hawkins, Steven W Kerr, Melanie S Dugas, Purushothaman K-Raman

JACC Cardiovasc Imaging· February 2018

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Intravascular ultrasound guided directional atherectomy versus directional atherectomy guided by angiography for the treatment of femoropopliteal in-stent restenosis.
Prakash Krishnan, Arthur Tarricone, Purushothaman K-Raman, Farhan Majeed, Vishal Kapur

Ther Adv Cardiovasc Dis· January 2018

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Corrigendum: Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability.
Solene M Evrard, Laura Lecce, Katherine C Michelis, Aya Nomura-Kitabayashi, Gaurav Pandey, K-Raman Purushothaman

Nat Commun· February 2017

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An Algorithm for the Use of Embolic Protection During Atherectomy for Femoral Popliteal Lesions.
Prakash Krishnan, Arthur Tarricone, K Raman Purushothaman, Meerarani Purushothaman, Miguel Vasquez

JACC Cardiovasc Interv· February 2017

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Enhanced neointimal fibroblast, myofibroblast content and altered extracellular matrix composition: Implications in the progression of human peripheral artery restenosis.
Prakash Krishnan, K-Raman Purushothaman, Meerarani Purushothaman, Irene C Turnbull, Arthur Tarricone

Atherosclerosis· August 2016

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Intravascular Ultrasound Is an Effective Tool for Predicting Histopathology-Confirmed Evidence of Adventitial Injury Following Directional Atherectomy for the Treatment of Peripheral Artery Disease.
Prakash Krishnan, Arthur Tarricone, Ziad Ali, K-Raman Purushothaman, Jessica Overbey

J Endovasc Ther· August 2016

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Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability.
Solene M Evrard, Laura Lecce, Katherine C Michelis, Aya Nomura-Kitabayashi, Gaurav Pandey, K-Raman Purushothaman

Nat Commun· June 2016

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Relation of Internal Elastic Lamellar Layer Disruption to Neointimal Cellular Proliferation and Type III Collagen Deposition in Human Peripheral Artery Restenosis.
Prakash Krishnan, K-Raman Purushothaman, Meerarani Purushothaman, Usman Baber, Arthur Tarricone

Am J Cardiol· April 2016

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Histopathological Evidence of Adventitial or Medial Injury Is a Strong Predictor of Restenosis During Directional Atherectomy for Peripheral Artery Disease.
Arthur Tarricone, Ziad Ali, Anitha Rajamanickam, Karthik Gujja, Vishal Kapur, K-Raman Purushothaman, Meerarani Purushothaman

J Endovasc Ther· October 2015

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Differential patterns of replacement and reactive fibrosis in pressure and volume overload are related to the propensity for ischaemia and involve resistin.
Elie R Chemaly, Soojeong Kang, Shihong Zhang, LaTronya McCollum, Jiqiu Chen, K-Raman Purushothaman

J Physiol· November 2013

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Expression of angiotensin-converting enzyme 2 and its end product angiotensin 1-7 is increased in diabetic atheroma: implications for inflammation and neovascularization.
K-Raman Purushothaman, Prakash Krishnan, Meerarani Purushothaman, Jose Wiley, Carlos L Alviar

Cardiovasc Pathol· May 2013

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Genotype-dependent impairment of hemoglobin clearance increases oxidative and inflammatory response in human diabetic atherosclerosis.
Meerarani Purushothaman, Prakash Krishnan, K-Raman Purushothaman, Usman Baber, Arthur Tarricone

Arterioscler Thromb Vasc Biol· November 2012

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Increased expression of oxidation-specific epitopes and apoptosis are associated with haptoglobin genotype: possible implications for plaque progression in human atherosclerosis.
K-Raman Purushothaman, Meerarani Purushothaman, Andrew P Levy, Patrick A Lento, Solene Evrard

J Am Coll Cardiol· July 2012

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Plaque neovascularization: defense mechanisms, betrayal, or a war in progress.
Pedro R Moreno, Meeranani Purushothaman, K-Raman Purushothaman

Ann N Y Acad Sci· April 2012

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Increased macrophage infiltration and neovascularization in congenital bicuspid aortic valve stenosis.
Pedro R Moreno, Luis Astudillo, Sammy Elmariah, K Raman Purushothaman, Meeranani Purushothaman

J Thorac Cardiovasc Surg· October 2011

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Long-term in vivo resistin overexpression induces myocardial dysfunction and remodeling in rats.
Elie R Chemaly, Lahouaria Hadri, Shihong Zhang, Maengjo Kim, Erik Kohlbrenner, Purushothaman K-Raman

J Mol Cell Cardiol· August 2011

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Inflammation, neovascularization and intra-plaque hemorrhage are associated with increased reparative collagen content: implication for plaque progression in diabetic atherosclerosis.
K-Raman Purushothaman, Meerarani Purushothaman, Paul Muntner, Patrick A Lento, William N O'Connor

Vasc Med· April 2011

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Coronary atherosclerosis in sudden cardiac death: an autopsy study.
M Lakshmi Sudha, Sandhya Sundaram, K Raman Purushothaman, P Sampath Kumar, D Prathiba

Indian J Pathol Microbiol· December 2009

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Increased neovascularization in advanced lipid-rich atherosclerotic lesions detected by gadofluorine-M-enhanced MRI: implications for plaque vulnerability.
Marc Sirol, Pedro R Moreno, K-Raman Purushothaman, Esad Vucic, Vardan Amirbekian

Circ Cardiovasc Imaging· September 2009

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Haptoglobin genotype is a major determinant of the amount of iron in the human atherosclerotic plaque.
Pedro R Moreno, K Raman Purushothaman, Meera Purushothaman, Paul Muntner, Nina S Levy

J Am Coll Cardiol· September 2008

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