Publications by authors named "Kaari Linask"

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A human forebrain organoid model phenocopies dysregulated RNA and protein homeostasis in ALS/FTD-associated TDP-43 proteinopathies.
Qi Zhang, Meng Liu, Xiaojuan Fan, Natalie Chin, Yue Xu, Kaari Linask

bioRxiv· November 2025

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Generation of induced pluripotent stem cell lines TRNDi037-A and TRNDi038-A from two patients with Alagille syndrome carrying heterozygous JAG1 mutations.
Elena F Evans, Guibin Chen, Ivan Pavlinov, Xiuli Huang, Kaari Linask

Stem Cell Res· February 2025

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Generation of an Alagille Syndrome (ALGS) patient-derived induced pluripotent stem cell line (TRNDi036-A) carrying a heterozygous mutation (p.Cys693*) in the JAG1 gene.
Omer Hatim, Miao Xu, Ivan Pavlinov, Kaari Linask, Jeanette Beers

Stem Cell Res· June 2024

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Generation of an Alagille syndrome (ALGS) patient-derived induced pluripotent stem cell line (TRNDi032-A) carrying a heterozygous mutation (p.Cys682Leufs*7) in the JAG1 gene.
Omer Hatim, Ivan Pavlinov, Miao Xu, Kaari Linask, Jeanette Beers

Stem Cell Res· December 2023

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Ligand-free mitochondria-localized mutant AR-induced cytotoxicity in spinal bulbar muscular atrophy.
Xia Feng, Xiu-Tang Cheng, Pengli Zheng, Yan Li, Jill Hakim, Kaari Linask

Brain· January 2023

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Eltrombopag Improves Erythroid Differentiation in a Human Induced Pluripotent Stem Cell Model of Diamond Blackfan Anemia.
Husam Qanash, Yongqin Li, Richard H Smith, Kaari Linask, Sara Young-Baird

Cells· March 2021

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Four induced pluripotent stem cell lines (TRNDi021-C, TRNDi023-D, TRNDi024-D and TRNDi025-A) generated from fibroblasts of four healthy individuals.
Xiaogang Xu, Manisha Pradhan, Miao Xu, Yu-Shan Cheng, Jeanette Beers, Kaari L Linask

Stem Cell Res· December 2020

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Generation of two tdTomato reporter induced pluripotent stem cell lines (NHLBIi003-A-1 and NHLBIi003-A-2) by AAVS1 safe harbor gene-editing.
Kira Patterson, Kaari L Linask, Jeanette Beers, Jizhong Zou

Stem Cell Res· January 2020

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Generation of two induced pluripotent stem cell lines (NHLBIi001-A and NHLBIi001-B) from a healthy Caucasian female volunteer with normal cardiac function.
Kira Patterson, Jeanette Beers, Kaari L Linask, Yongshun Lin, Shahin Hassanzadeh

Stem Cell Res· December 2019

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The ribosomal prolyl-hydroxylase OGFOD1 decreases during cardiac differentiation and modulates translation and splicing.
Andrea Stoehr, Leslie Kennedy, Yanqin Yang, Sajni Patel, Yongshun Lin, Kaari L Linask

JCI Insight· May 2019

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Efficient differentiation of cardiomyocytes and generation of calcium-sensor reporter lines from nonhuman primate iPSCs.
Yongshun Lin, Huimin Liu, Michael Klein, John Ostrominski, So Gun Hong, Kaari Linask

Sci Rep· April 2018

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Heparin Promotes Cardiac Differentiation of Human Pluripotent Stem Cells in Chemically Defined Albumin-Free Medium, Enabling Consistent Manufacture of Cardiomyocytes.
Yongshun Lin, Kaari L Linask, Barbara Mallon, Kory Johnson, Michael Klein

Stem Cells Transl Med· February 2017

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A cost-effective and efficient reprogramming platform for large-scale production of integration-free human induced pluripotent stem cells in chemically defined culture.
Jeanette Beers, Kaari L Linask, Jane A Chen, Lauren I Siniscalchi, Yongshun Lin

Sci Rep· June 2015

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The cAMP phosphodiesterase Prune localizes to the mitochondrial matrix and promotes mtDNA replication by stabilizing TFAM.
Fan Zhang, Yun Qi, Kiet Zhou, Guofeng Zhang, Kaari Linask

EMBO Rep· April 2015

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Evaluating the role of connexin43 in congenital heart disease: Screening for mutations in patients with outflow tract anomalies and the analysis of knock-in mouse models.
Guo-Ying Huang, Li-Jian Xie, Kaari L Linask, Chen Zhang, Xiao-Qing Zhao

J Cardiovasc Dis Res· October 2011

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Calcium channel blockade in embryonic cardiac progenitor cells disrupts normal cardiac cell differentiation.
Kaari L Linask, Kersti K Linask

Stem Cells Dev· December 2010

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Heterotaxy and complex structural heart defects in a mutant mouse model of primary ciliary dyskinesia.
Serena Y Tan, Julie Rosenthal, Xiao-Qing Zhao, Richard J Francis, Bishwanath Chatterjee, Kaari L Linask

J Clin Invest· December 2007

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Connexin 43-mediated modulation of polarized cell movement and the directional migration of cardiac neural crest cells.
Xin Xu, Richard Francis, Chih Jen Wei, Kaari L Linask, Cecilia W Lo

Development· September 2006

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High-throughput mouse genotyping using robotics automation.
Kaari L Linask, Cecilia W Lo

Biotechniques· February 2005

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Effects of antisense misexpression of CFC on downstream flectin protein expression during heart looping.
Kersti K Linask, Ming-Da Han, Kaari L Linask, Thomas Schlange, Thomas Brand

Dev Dyn· October 2003

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