Publications by authors named "Kae-Shin Sim"

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Erratum to "Ethnobotanical and alkaloid composition with their cytotoxicity of Tabernaemontana polyneura: A review with in silico ADMET analysis" [Fitoterapia 186 (2025) 106851].
Wen Xin Toh, Sin Yee Tang, Kae Shin Sim, Siew Huah Lim, Chun Hoe Tan

Fitoterapia· December 2025

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Ethnobotanical and alkaloid composition with their cytotoxicity of Tabernaemontana polyneura: A review with in silico ADMET analysis.
Wen Xin Toh, Sin Yee Tang, Kae Shin Sim, Siew Huah Lim, Chun Hoe Tan

Fitoterapia· October 2025

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Sialic acid detection and theranostic activity of phenylboronic acid-based fluorescent probe in human colorectal adenocarcinoma HT-29 cells.
Min Phin Ng, Wei Chuen Chan, Min Li Tan, Chun Hoe Tan, Sheena Yin Xin Tiong, Kae Shin Sim

Spectrochim Acta A Mol Biomol Spectrosc· January 2025

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Investigation of Phytochemical Composition, Radical Scavenging Potential, Anti-Obesogenic Effects, and Anti-Diabetic Activities of Kaempferia parviflora Rhizomes.
Sangeetha Prabakaran, Hazwani Mat Saad, Chun Hoe Tan, Syarifah Nur Syed Abdul Rahman, Kae Shin Sim

Chem Biodivers· January 2025

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Computational Elucidation of Hub Genes and Pathways Correlated with the Development of 5-Fluorouracil Resistance in HCT 116 Colorectal Carcinoma Cell Line.
Chun Hoe Tan, Siew Huah Lim, Kae Shin Sim

Biochem Genet· January 2025

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Structural insights and cytotoxicity evaluation of benz[e]indole pyrazolyl-substituted amides.
Abdul Qaiyum Ramle, Nadia Nabihah Mohd Yusof Chan, Min Phin Ng, Chun Hoe Tan, Kae Shin Sim

Mol Divers· June 2024

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Discovery of indoleninyl-pyrazolo[3,4-b]pyridines as potent chemotherapeutic agents against colorectal cancer cells.
Nur Husnaini Basir, Abdul Qaiyum Ramle, Min Phin Ng, Chun Hoe Tan, Edward R T Tiekink, Kae Shin Sim

Bioorg Chem· May 2024

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Antimicrobial and Antiproliferative Effects of Zingiberaceae Oils: A Natural Solution for Oral Health.
Muhammad Amirul Amil, Syarifah Nur Syed Abdul Rahman, Lee Fah Yap, Fathilah Abdul Razak, Marina Mohd Bakri, Kae Shin Sim

Chem Biodivers· March 2024

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Quinoline, Indole, and Isogranatanine Alkaloids from Malayan .
Yi-Sheng Tan, Min-Phin Ng, Chun-Hoe Tan, Wai-Kit Tang, Kae-Shin Sim

J Nat Prod· February 2024

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Polyneurines A-H, iboga alkaloids from Tabernaemontana polyneura.
Sin-Yee Tang, Chun-Hoe Tan, Kae-Shin Sim, Kien-Thai Yong, Kuan-Hon Lim

Phytochemistry· April 2023

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Antiproliferative and Microtubule-stabilizing Activities of Two Iboga-vobasine Bisindoles Alkaloids from Tabernaemontana corymbosa in Colorectal Adenocarcinoma HT-29 Cells.
Chun Hoe Tan, Dawn Su Yin Sim, Siew Huah Lim, Taznim Begam Mohd Mohidin, Gokula Mohan, Kae Shin Sim

Planta Med· November 2022

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Neuroprotective Properties of Wild Medicinal Mushroom, Sanguinoderma rugosum (Agaricomycetes), Extracts against Glutamate-Induced Hippocampal Cells.
Si Enn Sam, Kae Shin Sim, Syarifah Nur Syed Abdul Rahman, Yee Shin Tan

Int J Med Mushrooms· April 2022

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A rhodamine based chemosensor for solvent dependent chromogenic sensing of cobalt (II) and copper (II) ions with good selectivity and sensitivity: Synthesis, filter paper test strip, DFT calculations and cytotoxicity.
Wei Chuen Chan, Hazwani Mat Saad, Kae Shin Sim, Vannajan Sanghiran Lee, Chee Wei Ang

Spectrochim Acta A Mol Biomol Spectrosc· December 2021

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The Bisindole Alkaloids Angustilongines M and A from Induce Mitochondrial Apoptosis and G0/G1 Cell Cycle Arrest in HT-29 Cells through Promotion of Tubulin Polymerization.
Chun-Hoe Tan, Joanne Soon-Yee Yeap, Siew-Huah Lim, Yun-Yee Low, Kae-Shin Sim

J Nat Prod· May 2021

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Nickel and zinc complexes of testosterone N4-substituted thiosemicarbazone: Selective cytotoxicity towards human colorectal carcinoma cell line HCT 116 and their cell death mechanisms.
Mok Piew Heng, Kae Shin Sim, Kong Wai Tan

J Inorg Biochem· July 2020

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Cytotoxic and anticancer properties of the Malaysian mangrove pit viper () venom and its disintegrin (purpureomaculin).
Choo Hock Tan, Jia Lee Liew, Suerialoasan Navanesan, Kae Shin Sim, Nget Hong Tan

J Venom Anim Toxins Incl Trop Dis· July 2020

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Macroline-Sarpagine Bisindole Alkaloids with Antiproliferative Activity from .
Joanne Soon-Yee Yeap, Hazwani Mat Saad, Chun-Hoe Tan, Kae-Shin Sim, Siew-Huah Lim

J Nat Prod· November 2019

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Physiological and metabolic responses of (Chlorophyceae) to nickel toxicity and warming.
Wai-Kuan Yong, Kae-Shin Sim, Sze-Wan Poong, Dong Wei, Siew-Moi Phang

3 Biotech· August 2019

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A Cytotoxic Indole Characterized by Incorporation of a Unique Carbon-Nitrogen Skeleton and Two Pentacyclic Corynanthean Alkaloids Incorporating a Substituted Tetrahydrofuranone Ring from .
Soon-Kit Wong, Suet-Pick Wong, Kae-Shin Sim, Siew-Huah Lim, Yun-Yee Low

J Nat Prod· July 2019

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Conolodinines A-D, Aspidosperma- Aspidosperma Bisindole Alkaloids with Antiproliferative Activity from Tabernaemontana corymbosa.
Dawn Su-Yin Sim, Suerialoasan Navanesan, Kae-Shin Sim, Subramaniam Gurusamy, Siew-Huah Lim

J Nat Prod· April 2019

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Antimelanogenesis and Anti-Inflammatory Activity of Selected Culinary-Medicinal Mushrooms.
Hazwani Mat Saad, Kae Shin Sim, Yee Shin Tan

Int J Med Mushrooms· September 2018

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Ajmaline, Oxindole, and Cytotoxic Macroline-Akuammiline Bisindole Alkaloids from Alstonia penangiana.
Joanne Soon-Yee Yeap, Suerialoasan Navanesan, Kae-Shin Sim, Kien-Thai Yong, Subramaniam Gurusamy

J Nat Prod· May 2018

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Size-dependent effect of cystine/citric acid-capped confeito-like gold nanoparticles on cellular uptake and photothermal cancer therapy.
Wen Shang Saw, Masaki Ujihara, Wu Yi Chong, Siew Hui Voon, Toyoko Imae, Kae Shin Sim

Colloids Surf B Biointerfaces· January 2018

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Intrinsic capabilities of Leptospermum javanicum in inducing apoptosis and suppressing the metastatic potential of human lung carcinoma cells.
Suerialoasan Navanesan, Norhanom Abdul Wahab, Sugumaran Manickam, Yuen Lin Cheow, Kae Shin Sim

Chem Biol Interact· August 2017

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Antiproliferation effect of guanosine on HCT 116 cells involves MAPK and AMPK pathways.
Wuen Yew Teoh, Norhanom Abdul Wahab, Kae Shin Sim

Nucleosides Nucleotides Nucleic Acids· April 2017

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