Publications by authors named "Kaido Viht"

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Conjugates of adenosine mimetics and arginine-rich peptides serve as inhibitors and fluorescent probes but not as long-lifetime photoluminescent probes for protein arginine methyltransferases.
Darja Lavogina, Naila Nasirova, Tanel Sõrmus, Taavo Tähtjärv, Erki Enkvist, Kaido Viht

J Pept Sci· March 2023

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Deactivatable Bisubstrate Inhibitors of Protein Kinases.
Tanel Sõrmus, Darja Lavogina, Erki Enkvist, Asko Uri, Kaido Viht

Molecules· October 2022

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Construction of Covalent Bisubstrate Inhibitor of Protein Kinase Reacting with Cysteine Residue at Substrate-Binding Site.
Tanel Sõrmus, Darja Lavogina, Anu Teearu, Erki Enkvist, Asko Uri, Kaido Viht

J Med Chem· August 2022

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Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization.
Darja Lavogina, Artjom Stepanjuk, Maire Peters, Külli Samuel, Sergo Kasvandik, Kaido Viht

Hum Reprod· July 2021

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Crystal Structure-Guided Design of Bisubstrate Inhibitors and Photoluminescent Probes for Protein Kinases of the PIM Family.
Olivier E Nonga, Darja Lavogina, Erki Enkvist, Katrin Kestav, Apirat Chaikuad, Kaido Viht

Molecules· July 2021

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Discovery of strong inhibitory properties of a monoclonal antibody of PKA and use of the antibody and a competitive photoluminescent orthosteric probe for analysis of the protein kinase.
Olivier Etebe Nonga, Darja Lavogina, Taavi Ivan, Kaido Viht, Erki Enkvist

Biochim Biophys Acta Proteins Proteom· August 2020

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Unexpected CK2β-antagonistic functionality of bisubstrate inhibitors targeting protein kinase CK2.
Markus Pietsch, Kaido Viht, Alexander Schnitzler, Ramesh Ekambaram, Michaela Steinkrüger

Bioorg Chem· March 2020

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Efficient photocaging of a tight-binding bisubstrate inhibitor of cAMP-dependent protein kinase.
Tanel Sõrmus, Darja Lavogina, Erki Enkvist, Asko Uri, Kaido Viht

Chem Commun (Camb)· September 2019

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Thiazole- and selenazole-comprising high-affinity inhibitors possess bright microsecond-scale photoluminescence in complex with protein kinase CK2.
Jürgen Vahter, Kaido Viht, Asko Uri, Ganesh Babu Manoharan, Erki Enkvist

Bioorg Med Chem· October 2018

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A Selective Biligand Inhibitor of CK2 Increases Caspase-3 Activity in Cancer Cells and Inhibits Platelet Aggregation.
Hedi Rahnel, Kaido Viht, Darja Lavogina, Olga Mazina, Tõiv Haljasorg

ChemMedChem· October 2017

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Binding assay for characterization of protein kinase inhibitors possessing sub-picomolar to sub-millimolar affinity.
Hedi Sinijarv, Shanshan Wu, Taavi Ivan, Tonis Laasfeld, Kaido Viht

Anal Biochem· August 2017

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Slowly on, Slowly off: Bisubstrate-Analogue Conjugates of 5-Iodotubercidin and Histone H3 Peptide Targeting Protein Kinase Haspin.
Katrin Kestav, Kaido Viht, Anton Konovalov, Erki Enkvist, Asko Uri

Chembiochem· April 2017

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Oligo-aspartic acid conjugates with benzo[c][2,6]naphthyridine-8-carboxylic acid scaffold as picomolar inhibitors of CK2.
Jürgen Vahter, Kaido Viht, Asko Uri, Erki Enkvist

Bioorg Med Chem· April 2017

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Acetoxymethyl Ester of Tetrabromobenzimidazole-Peptoid Conjugate for Inhibition of Protein Kinase CK2 in Living Cells.
Kaido Viht, Siiri Saaver, Jürgen Vahter, Erki Enkvist, Darja Lavogina

Bioconjug Chem· December 2015

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FRET-based screening assay using small-molecule photoluminescent probes in lysate of cells overexpressing RFP-fused protein kinases.
Ganesh Babu Manoharan, Erki Enkvist, Marje Kasari, Kaido Viht, Michael Zenn

Anal Biochem· July 2015

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Benzoselenadiazole-based responsive long-lifetime photoluminescent probes for protein kinases.
Ramesh Ekambaram, Erki Enkvist, Ganesh babu Manoharan, Mihkel Ugandi, Marje Kasari, Kaido Viht

Chem Commun (Camb)· April 2014

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Long residence times revealed by Aurora A kinase-targeting fluorescent probes derived from inhibitors MLN8237 and VX-689.
Darja Lavogina, Erki Enkvist, Kaido Viht, Asko Uri

Chembiochem· February 2014

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Responsive microsecond-lifetime photoluminescent probes for analysis of protein kinases and their inhibitors.
Marje Kasari, Kadri Ligi, J A Gareth Williams, Angela Vaasa, Erki Enkvist, Kaido Viht

Biochim Biophys Acta· July 2013

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A subnanomolar fluorescent probe for protein kinase CK2 interaction studies.
Erki Enkvist, Kaido Viht, Nils Bischoff, Jürgen Vahter, Siiri Saaver

Org Biomol Chem· November 2012

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Bisubstrate fluorescent probes and biosensors in binding assays for HTS of protein kinase inhibitors.
Asko Uri, Marje Lust, Angela Vaasa, Darja Lavogina, Kaido Viht

Biochim Biophys Acta· March 2010

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High-affinity bisubstrate probe for fluorescence anisotropy binding/displacement assays with protein kinases PKA and ROCK.
Angela Vaasa, Indrek Viil, Erki Enkvist, Kaido Viht, Gerda Raidaru

Anal Biochem· February 2009

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Surface-plasmon-resonance-based biosensor with immobilized bisubstrate analog inhibitor for the determination of affinities of ATP- and protein-competitive ligands of cAMP-dependent protein kinase.
Kaido Viht, Sonja Schweinsberg, Marje Lust, Angela Vaasa, Gerda Raidaru

Anal Biochem· March 2007

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Conjugation of adenosine and hexa-(D-arginine) leads to a nanomolar bisubstrate-analog inhibitor of basophilic protein kinases.
Erki Enkvist, Darja Lavogina, Gerda Raidaru, Angela Vaasa, Indrek Viil, Kaido Viht

J Med Chem· November 2006

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Fluorometric TLC assay for evaluation of protein kinase inhibitors.
Kaido Viht, Angela Vaasa, Gerda Raidaru, Erki Enkvist, Asko Uri

Anal Biochem· May 2005

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Protein cargo delivery properties of cell-penetrating peptides. A comparative study.
Pille Säälik, Anna Elmquist, Mats Hansen, Kärt Padari, Külliki Saar, Kaido Viht

Bioconjug Chem· April 2005

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