Publications by authors named "Kan Shida"

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strain Shirota suppresses upper respiratory tract infections and activates mononuclear phagocytic cells in healthy Japanese office workers: a randomized, double-blind, controlled trial.
Tomoaki Naito, Masatoshi Morikawa, Ayaka Maki, Noriko Kato-Nagaoka, Yuya Hagihira, Kan Shida

Biosci Microbiota Food Health· April 2025

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Detection of Glycolytically Active Lacticaseibacillus paracasei Strain Shirota by Flow Cytometry Targeting the Efflux Activity of Fluorescent Dye: a Potential Tool for Quality Assessment of Probiotic Cells in Milk Products.
Hiroyuki Kubota, Masaki Serata, Hoshitaka Matsumoto, Kan Shida, Takekazu Okumura

Appl Environ Microbiol· April 2023

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Diverse impact of a probiotic strain, Shirota, on peripheral mononuclear phagocytic cells in healthy Japanese office workers: a randomized, double-blind, controlled trial.
Tomoaki Naito, Masatoshi Morikawa, Mayuko Yamamoto-Fujimura, Akira Iwata, Ayaka Maki, Kan Shida

Biosci Microbiota Food Health· October 2022

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Effects of citrus juice fermented with YIT 0132 on Japanese cedar pollinosis during probiotic consumption: an open study.
Sayaka Kakiyama, Norihiro Kubota, Kan Shida, Naomi Harima-Mizusawa

Biosci Microbiota Food Health· March 2020

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Probiotics into outer space: feasibility assessments of encapsulated freeze-dried probiotics during 1 month's storage on the International Space Station.
Takafumi Sakai, Yasuhiro Moteki, Takuya Takahashi, Kan Shida, Mayumi Kiwaki

Sci Rep· July 2018

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Short communication: Probiotic induction of interleukin-10 and interleukin-12 production by macrophages is modulated by co-stimulation with microbial components.
Rumi Kaji, Junko Kiyoshima-Shibata, Satoshi Tsujibe, Masanobu Nanno, Kan Shida

J Dairy Sci· April 2018

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Microbiota of the Small Intestine Is Selectively Engulfed by Phagocytes of the Lamina Propria and Peyer's Patches.
Masatoshi Morikawa, Satoshi Tsujibe, Junko Kiyoshima-Shibata, Yohei Watanabe, Noriko Kato-Nagaoka, Kan Shida

PLoS One· June 2017

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Daily intake of fermented milk with Lactobacillus casei strain Shirota reduces the incidence and duration of upper respiratory tract infections in healthy middle-aged office workers.
Kan Shida, Tadashi Sato, Ryoko Iizuka, Ryotaro Hoshi, Osamu Watanabe

Eur J Nutr· February 2017

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Enhanced differentiation of intraepithelial lymphocytes in the intestine of polymeric immunoglobulin receptor-deficient mice.
Noriko Kato-Nagaoka, Shin-Ichiro Shimada, Yoko Yamakawa, Satoshi Tsujibe, Tomoaki Naito, Kan Shida

Immunology· September 2015

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Enhanced Immunostimulating Activity of Lactobacilli-Mimicking Materials by Controlling Size.
Koji Nagahama, Takayuki Kumano, Yuichi Nakagawa, Naho Oyama, Hirokazu Tsuji, Kan Shida

Bioconjug Chem· August 2015

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Synthesis and immunestimulating activity of lactobacilli-originated polysaccharide-polymeric microparticle conjugates.
Koji Nagahama, Takayuki Kumano, Tsubasa Nakata, Hirokazu Tsuji, Kaoru Moriyama, Kan Shida

Langmuir· February 2015

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Beneficial Effects of Citrus Juice Fermented with Lactobacillus plantarum YIT 0132 on Japanese Cedar Pollinosis.
Naomi Harima-Mizusawa, Tohru Iino, Norie Onodera-Masuoka, Noriko Kato-Nagaoka, Junko Kiyoshima-Shibata, Kan Shida

Biosci Microbiota Food Health· November 2014

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Probiotics as efficient immunopotentiators: translational role in cancer prevention.
Kan Shida, Koji Nomoto

Indian J Med Res· November 2013

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Probiotic upregulation of peripheral IL-17 responses does not exacerbate neurological symptoms in experimental autoimmune encephalomyelitis mouse models.
Toshihide Kobayashi, Tomomi Suzuki, Rumi Kaji, Masaki Serata, Tsuyoshi Nagata, Kan Shida

Immunopharmacol Immunotoxicol· June 2012

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Flexible cytokine production by macrophages and T cells in response to probiotic bacteria: a possible mechanism by which probiotics exert multifunctional immune regulatory activities.
Kan Shida, Masanobu Nanno, Satoru Nagata

Gut Microbes· October 2011

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Well-controlled proinflammatory cytokine responses of Peyer's patch cells to probiotic Lactobacillus casei.
Yukihide Chiba, Kan Shida, Satoru Nagata, Mariko Wada, Lei Bian

Immunology· July 2010

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Bacterial teichoic acids reverse predominant IL-12 production induced by certain lactobacillus strains into predominant IL-10 production via TLR2-dependent ERK activation in macrophages.
Rumi Kaji, Junko Kiyoshima-Shibata, Masato Nagaoka, Masanobu Nanno, Kan Shida

J Immunol· April 2010

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Oral administration of probiotic bacteria, Lactobacillus casei and Bifidobacterium breve, does not exacerbate neurological symptoms in experimental autoimmune encephalomyelitis.
Toshihide Kobayashi, Ikuo Kato, Masanobu Nanno, Kan Shida, Kazumoto Shibuya

Immunopharmacol Immunotoxicol· March 2010

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Immune deviation and alleviation of allergic reactions in mice subjected to dietary restriction.
Ken-ichi Yamazaki, Noriko Kato-Nagaoka, Tomomi Suzuki, Kan Shida, Masanobu Nanno

Biosci Biotechnol Biochem· December 2009

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Peptidoglycan from lactobacilli inhibits interleukin-12 production by macrophages induced by Lactobacillus casei through Toll-like receptor 2-dependent and independent mechanisms.
Kan Shida, Junko Kiyoshima-Shibata, Rumi Kaji, Masato Nagaoka, Masanobu Nanno

Immunology· September 2009

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Probiotics and immunology: separating the wheat from the chaff.
Kan Shida, Masanobu Nanno

Trends Immunol· November 2008

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Effects of probiotics on allergic rhinitis induced by Japanese cedar pollen: randomized double-blind, placebo-controlled clinical trial.
Manabu Tamura, Takashi Shikina, Tetsuo Morihana, Masaki Hayama, Osami Kajimoto, Kan Shida

Int Arch Allergy Immunol· May 2007

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Essential roles of monocytes in stimulating human peripheral blood mononuclear cells with Lactobacillus casei to produce cytokines and augment natural killer cell activity.
Kan Shida, Tomomi Suzuki, Junko Kiyoshima-Shibata, Shin-Ichiro Shimada, Masanobu Nanno

Clin Vaccine Immunol· September 2006

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Augmentation of cellular immunity and reduction of influenza virus titer in aged mice fed Lactobacillus casei strain Shirota.
Tetsuji Hori, Junko Kiyoshima, Kan Shida, Hisako Yasui

Clin Diagn Lab Immunol· January 2002

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