Publications by authors named "Kaoru Saigo"

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RNAi-mediated knockdown of mouse melanocortin-4 receptor in vitro and in vivo, using an siRNA expression construct based on the mir-187 precursor.
Minoru Kato, Yi-Ying Huang, Mina Matsuo, Yoko Takashina, Kazuyo Sasaki, Kaoru Saigo

Exp Anim· January 2017

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Multipotent versus differentiated cell fate selection in the developing Drosophila airways.
Ryo Matsuda, Chie Hosono, Christos Samakovlis, Kaoru Saigo

Elife· December 2015

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The intersection of the extrinsic hedgehog and WNT/wingless signals with the intrinsic Hox code underpins branching pattern and tube shape diversity in the drosophila airways.
Ryo Matsuda, Chie Hosono, Kaoru Saigo, Christos Samakovlis

PLoS Genet· January 2015

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Interactions between the non-seed region of siRNA and RNA-binding RLC/RISC proteins, Ago and TRBP, in mammalian cells.
Tomoko Takahashi, Shuhei Zenno, Osamu Ishibashi, Toshihiro Takizawa, Kaoru Saigo

Nucleic Acids Res· April 2014

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Essential notes regarding the design of functional siRNAs for efficient mammalian RNAi.
Kumiko Ui-Tei, Yuki Naito, Kaoru Saigo

J Biomed Biotechnol· June 2010

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Cooperative DNA-binding and sequence-recognition mechanism of aristaless and clawless.
Ken-ichi Miyazono, Yuehua Zhi, Yuriko Takamura, Koji Nagata, Kaoru Saigo

EMBO J· May 2010

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RNAi-mediated knockdown showing impaired cell survival in Drosophila wing imaginal disc.
Makoto Umemori, Okiko Habara, Tatsunori Iwata, Kousuke Maeda, Kana Nishinoue, Kaoru Saigo

Gene Regul Syst Bio· February 2009

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Hox genes regulate the same character by different strategies in each segment.
Takuya Tsubota, Kaoru Saigo, Tetsuya Kojima

Mech Dev· December 2008

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Thermodynamic stability and Watson-Crick base pairing in the seed duplex are major determinants of the efficiency of the siRNA-based off-target effect.
Kumiko Ui-Tei, Yuki Naito, Kenji Nishi, Aya Juni, Kaoru Saigo

Nucleic Acids Res· December 2008

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Expansion of substrate specificity and catalytic mechanism of azoreductase by X-ray crystallography and site-directed mutagenesis.
Kosuke Ito, Masayuki Nakanishi, Woo-Cheol Lee, Yuehua Zhi, Hiroshi Sasaki, Kaoru Saigo

J Biol Chem· May 2008

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Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect.
Kumiko Ui-Tei, Yuki Naito, Shuhei Zenno, Kenji Nishi, Kenji Yamato, Kaoru Saigo

Nucleic Acids Res· April 2008

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Introduction of silencing-inducing transgene against Fgf19 does not affect expression of Tbx5 and beta3-tubulin in the developing chicken retina.
Mayumi Okamoto, Sayuri Tomonari, Yuki Naito, Kaoru Saigo, Sumihare Noji

Dev Growth Differ· March 2008

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17beta-estradiol at physiological concentrations augments Ca(2+) -activated K+ currents via estrogen receptor beta in the gonadotropin-releasing hormone neuronal cell line GT1-7.
Ichiro Nishimura, Kumiko Ui-Tei, Kaoru Saigo, Hirotaka Ishii, Yasuo Sakuma

Endocrinology· February 2008

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Heparan sulfate regulates self-renewal and pluripotency of embryonic stem cells.
Norihiko Sasaki, Kazuhiko Okishio, Kumiko Ui-Tei, Kaoru Saigo, Akiko Kinoshita-Toyoda

J Biol Chem· February 2008

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Homodimeric structure and double-stranded RNA cleavage activity of the C-terminal RNase III domain of human dicer.
Daijiro Takeshita, Shuhei Zenno, Woo Cheol Lee, Koji Nagata, Kaoru Saigo

J Mol Biol· November 2007

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Optimal design and validation of antiviral siRNA for targeting HIV-1.
Yuki Naito, Kyoko Nohtomi, Toshinari Onogi, Rie Uenishi, Kumiko Ui-Tei, Kaoru Saigo

Retrovirology· November 2007

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Crystal structure of the PIN domain of human telomerase-associated protein EST1A.
Daijiro Takeshita, Shuhei Zenno, Woo Cheol Lee, Kaoru Saigo, Masaru Tanokura

Proteins· September 2007

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Cellular internalization of green fluorescent protein fused with herpes simplex virus protein VP22 via a lipid raft-mediated endocytic pathway independent of caveolae and Rho family GTPases but dependent on dynamin and Arf6.
Kenji Nishi, Kaoru Saigo

J Biol Chem· September 2007

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Establishment of cell lines derived from the rat suprachiasmatic nucleus.
Soshi Kawaguchi, Atsuki Shinozaki, Masuo Obinata, Kaoru Saigo, Yoshiyuki Sakaki

Biochem Biophys Res Commun· April 2007

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Guidelines for the selection of effective short-interfering RNA sequences for functional genomics.
Kumiko Ui-Tei, Yuki Naito, Kaoru Saigo

Methods Mol Biol· March 2007

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Fate determination of Drosophila leg distal regions by trachealess and tango through repression and stimulation, respectively, of Bar homeobox gene expression in the future pretarsus and tarsus.
Reiko Tajiri, Takuya Tsuji, Ryu Ueda, Kaoru Saigo, Tetsuya Kojima

Dev Biol· March 2007

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A female-biased expressed elongase involved in long-chain hydrocarbon biosynthesis and courtship behavior in Drosophila melanogaster.
Thomas Chertemps, Line Duportets, Carole Labeur, Ryu Ueda, Kuniaki Takahashi, Kaoru Saigo

Proc Natl Acad Sci U S A· March 2007

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LARK activates posttranscriptional expression of an essential mammalian clock protein, PERIOD1.
Shihoko Kojima, Ken Matsumoto, Matsumi Hirose, Miyuki Shimada, Mamoru Nagano, Kaoru Saigo

Proc Natl Acad Sci U S A· February 2007

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Polarized exocytosis and transcytosis of Notch during its apical localization in Drosophila epithelial cells.
Nobuo Sasaki, Takeshi Sasamura, Hiroyuki O Ishikawa, Maiko Kanai, Ryu Ueda, Kaoru Saigo

Genes Cells· January 2007

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Fate map of the distal portion of Drosophila proboscis as inferred from the expression and mutations of basic patterning genes.
Keiichiro Yasunaga, Kaoru Saigo, Tetsuya Kojima

Mech Dev· December 2006

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