Publications by authors named "Kaoru Uchimaru"

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Correction: A comprehensive assessment using multiple factors based on HAS-Flow analysis predicts ATL development and progression.
Hideaki Nakamura, Tatsuro Watanabe, Akemi Sato, Atsushi Kawaguchi, Kaoru Uchimaru

Sci Rep· December 2025

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mA RNA Modification Controls HTLV-1 Tax and Host Gene Expression.
Rei Gibu, Kodai Gibu, Kako Suzuki, Yuetsu Tanaka, Kaoru Uchimaru

Genes Cells· November 2025

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A viral clonality evenness score to predict progression to adult T-cell leukaemia in asymptomatic carriers of human T-lymphotropic virus type 1 in Japan: a retrospective longitudinal cohort study.
Snehal Dilip Karpe, Maria Artesi, Jérôme Wayet, Keith Durkin, Vincent Hahaut, Kaoru Uchimaru

Lancet Microbe· November 2025

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Chromatin remodeling enhances MAP3K8 expression in HAM: a key pathogenesis for therapeutic intervention.
Makoto Nakashima, Kaho Nagai, Naoki Takao, Natsumi Araya, Yuuta Kuze, Kaoru Uchimaru

Nat Commun· November 2025

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Clonality analysis of HTLV-1-infected cells enhances prognostic precision in smoldering adult T-cell leukemia/ lymphoma.
Masumichi Saito, Tomoo Sato, Hiroo Hasegawa, Kenichiro Tanabe, Hazuka Yoshida-Furihata, Kaoru Uchimaru

Haematologica· October 2025

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Bidirectional anti-tumor and immunological strategies by targeting GARP-TGF-β axis in adult T-cell leukemia/lymphoma.
Kako Suzuki, Seina Kusayanagi, Yuta Kuze, Masato Hata, Shiho Kozuma, Kaoru Uchimaru

Leukemia· October 2025

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Prognostic impact of organ involvement in aggressive adult T-cell leukemia/lymphoma: definition of risk organ and proposal of a prognostic index.
Koji Jimbo, Ayumu Ito, Hirona Ichimura, Junichi Kuroda, Shohei Andoh, Kaoru Uchimaru

Blood Cancer J· October 2025

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Bridging therapy with valemetostat to allogeneic hematopoietic cell transplantation for adult T-cell leukemia/lymphoma.
Shota Furukawa, Ayumu Ito, Koji Jimbo, Masataka Sakashita, Sakiko Harada, Kaoru Uchimaru

J Clin Exp Hematop· September 2025

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Outcomes of patients aged 70 years or younger with aggressive ATL at core hospitals for ATL treatment in Tokyo.
Junya Makiyama, Nobuhiro Ohno, Koji Jimbo, Toyotaka Kawamata, Kazuaki Yokoyama, Kaoru Uchimaru

Int J Hematol· September 2025

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A comprehensive assessment using multiple factors based on HAS-Flow analysis predicts ATL development and progression.
Hideaki Nakamura, Tatsuro Watanabe, Akemi Sato, Atsushi Kawaguchi, Kaoru Uchimaru

Sci Rep· July 2025

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Virus-induced RGMa expression drives neurodegeneration in HTLV-1-associated myelopathy.
Natsumi Araya, Makoto Yamagishi, Makoto Nakashima, Naomi Asahara, Kazuhiro Kiyohara, Kaoru Uchimaru

JCI Insight· June 2025

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Improving outcome prediction in indolent ATL by subdividing intermediate risk into low- and high-intermediate groups.
Shigeo Fuji, Masahito Tokunaga, Atae Utsunomiya, Junya Makiyama, Youko Suehiro, Kaoru Uchimaru

Ann Hematol· April 2025

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Enhancer of zeste homolog 1/2 dual inhibitor valemetostat outperforms enhancer of zeste homolog 2-selective inhibitors in reactivating latent HIV-1 reservoirs .
Ayako Sedohara, Tomohiko Koibuchi, Makoto Yamagishi, Michiko Koga, Kotaro Arizono, Kaoru Uchimaru

Front Microbiol· April 2025

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Virus-host immune interaction in asymptomatic HTLV-1 carriers.
Theodore Worlanyo Asigbee, Midori Nakamura-Hoshi, Nozomi Kuse, Hiroshi Ishii, Koichi Ishikawa, Kaoru Uchimaru

Microbiol Spectr· March 2025

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Rewired chromatin structure and epigenetic gene dysregulation during HTLV-1 infection to leukemogenesis.
Jun Mizuike, Kako Suzuki, Shu Tosaka, Yuta Kuze, Seiichiro Kobayashi, Kaoru Uchimaru

Cancer Sci· February 2025

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Long-term kinetics of proviral load in HTLV-1 carriers: defining risk for the development of adult T-cell leukemia/lymphoma.
Koji Jimbo, Masanori Nojima, Keiko Toriuchi, Makoto Yamagishi, Makoto Nakashima, Kaoru Uchimaru

Biomark Res· February 2025

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Prognosis of aggressive adult T-cell leukemia/lymphoma with central nervous system infiltration and utility of CD7 versus CADM1 flowcytometric plots of cerebrospinal fluid.
Koji Jimbo, Tomohiro Ishigaki, Masataka Sakashita, Shohei Andoh, Hirona Ichimura, Kaoru Uchimaru

Ann Hematol· January 2025

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Sexual transmission of HTLV-1 resulting in uveitis with short-term latency and low proviral load.
Koju Kamoi, Kaoru Uchimaru, Yasuhito Nannya, Arinobu Tojo, Toshiki Watanabe

J Med Virol· October 2024

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Plasma vitamin D levels are correlated with the pathogenesis of human T-cell leukemia virus type 1-associated diseases.
Yasuko Sagara, Hitomi Nakamura, Yasuhiro Sagara, Etsuko Shitsuta, Kaoru Uchimaru

J Med Virol· September 2024

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Flow cytometric profiles with CD7 and CADM1 in CD4+ T cells are promising indicators for prognosis of aggressive ATL.
Koji Jimbo, Toyotaka Kawamata, Yoshihiro Inamoto, Ayumu Ito, Kazuaki Yokoyama, Kaoru Uchimaru

Blood Adv· July 2024

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Mechanisms of action and resistance in histone methylation-targeted therapy.
Makoto Yamagishi, Yuta Kuze, Seiichiro Kobayashi, Makoto Nakashima, Satoko Morishima, Kaoru Uchimaru

Nature· March 2024

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Progression of adult T-cell leukemia/lymphoma from smoldering to acute type due to branched subclonal evolution.
Koji Jimbo, Makoto Yamagishi, Yutaka Suzuki, Kako Suzuki, Motoko Mizukami, Kaoru Uchimaru

EJHaem· November 2023

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Measures for the Prevention of Mother-to-Child Human T-Cell Leukemia Virus Type 1 Transmission in Japan: The Burdens of HTLV-1-Infected Mothers.
Kaoru Uchimaru, Kazuo Itabashi

Viruses· September 2023

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HTLV-1 cell-free DNA in plasma as a potential biomarker in HTLV-1 carriers and adult T-cell leukemia-lymphoma.
Hiroo Katsuya, Hideaki Nakamura, Aya Maeda, Keitaro Ishii, Toshiaki Nagaie, Kaoru Uchimaru

EJHaem· August 2023

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EZH1/2 dual inhibitors suppress HTLV-1-infected cell proliferation and hyperimmune response in HTLV-1-associated myelopathy.
Akihito Koseki, Natsumi Araya, Makoto Yamagishi, Junji Yamauchi, Naoko Yagishita, Kaoru Uchimaru

Front Microbiol· June 2023

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