Publications by authors named "Kara Hunter"

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Protein surface chemistry encodes an adaptive tolerance to desiccation.
Paulette Sofía Romero-Pérez, Haley M Moran, David P Cordone, Azeem Horani, Alexander Truong, Kara Hunter

Cell Syst· October 2025

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Protein surface chemistry encodes an adaptive tolerance to desiccation.
Paulette Sofía Romero-Pérez, Haley M Moran, Azeem Horani, Alexander Truong, Edgar Manriquez-Sandoval, Kara Hunter

bioRxiv· October 2024

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Capturing the systemic immune signature of a norovirus infection: an n-of-1 case study within a clinical trial.
Antony J Cutler, Joao Oliveira, Ricardo C Ferreira, Ben Challis, Neil M Walker, Kara M D Hunter

Wellcome Open Res· October 2017

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Regulatory T Cell Responses in Participants with Type 1 Diabetes after a Single Dose of Interleukin-2: A Non-Randomised, Open Label, Adaptive Dose-Finding Trial.
John A Todd, Marina Evangelou, Antony J Cutler, Marcin L Pekalski, Neil M Walker, Kara M D Hunter

PLoS Med· October 2016

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Investigation of soluble and transmembrane CTLA-4 isoforms in serum and microvesicles.
Laura Esposito, Kara M D Hunter, Jan Clark, Daniel B Rainbow, Helen Stevens

J Immunol· July 2014

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Genetic interactions among Idd3, Idd5.1, Idd5.2, and Idd5.3 protective loci in the nonobese diabetic mouse model of type 1 diabetes.
Xiaotian Lin, Emma E Hamilton-Williams, Daniel B Rainbow, Kara M Hunter, Yang D Dai

J Immunol· April 2013

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Cellular mechanisms of restored β-cell tolerance mediated by protective alleles of Idd3 and Idd5.
Emma E Hamilton-Williams, Jocelyn Cheung, Daniel B Rainbow, Kara M Hunter, Linda S Wicker

Diabetes· January 2012

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CD8 T cells mediate direct biliary ductule damage in nonobese diabetic autoimmune biliary disease.
Guo-Xiang Yang, Yuehong Wu, Hiroki Tsukamoto, Patrick S Leung, Zhe-Xiong Lian, Kara M Hunter

J Immunol· January 2011

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Idd9.2 and Idd9.3 protective alleles function in CD4+ T-cells and nonlymphoid cells to prevent expansion of pathogenic islet-specific CD8+ T-cells.
Emma E Hamilton-Williams, S B Justin Wong, Xavier Martinez, Daniel B Rainbow, Kara M Hunter

Diabetes· June 2010

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Idd9.1 locus controls the suppressive activity of FoxP3+CD4+CD25+ regulatory T-cells.
Jun Yamanouchi, Maria-Carmen Puertas, Joan Verdaguer, Paul A Lyons, Daniel B Rainbow, Kara M Hunter

Diabetes· January 2010

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Genetic evidence that the differential expression of the ligand-independent isoform of CTLA-4 is the molecular basis of the Idd5.1 type 1 diabetes region in nonobese diabetic mice.
Manabu Araki, Denise Chung, Sue Liu, Daniel B Rainbow, Giselle Chamberlain, Kara M D Hunter

J Immunol· October 2009

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Expression of diabetes-associated genes by dendritic cells and CD4 T cells drives the loss of tolerance in nonobese diabetic mice.
Emma E Hamilton-Williams, Xavier Martinez, Jan Clark, Sarah Howlett, Kara M Hunter

J Immunol· August 2009

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Commonality in the genetic control of Type 1 diabetes in humans and NOD mice: variants of genes in the IL-2 pathway are associated with autoimmune diabetes in both species.
Dan B Rainbow, Laura Esposito, Sarah K Howlett, Kara M Hunter, John A Todd

Biochem Soc Trans· June 2008

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Interactions between Idd5.1/Ctla4 and other type 1 diabetes genes.
Kara Hunter, Dan Rainbow, Vincent Plagnol, John A Todd, Laurence B Peterson

J Immunol· December 2007

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The use of idd congenic mice to identify checkpoints of peripheral tolerance to islet antigen.
Emma E Hamilton-Williams, Xavier Martinez, Michael Lyman, Kara Hunter, Linda S Wicker

Ann N Y Acad Sci· April 2007

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Interleukin-2 gene variation impairs regulatory T cell function and causes autoimmunity.
Jun Yamanouchi, Dan Rainbow, Pau Serra, Sarah Howlett, Kara Hunter

Nat Genet· March 2007

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Genes within the Idd5 and Idd9/11 diabetes susceptibility loci affect the pathogenic activity of B cells in nonobese diabetic mice.
Pablo A Silveira, Harold D Chapman, Jessica Stolp, Ellis Johnson, S Lewis Cox, Kara Hunter

J Immunol· November 2006

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A 20-Mb region of chromosome 4 controls TNF-alpha-mediated CD8+ T cell aggression toward beta cells in type 1 diabetes.
Giselle Chamberlain, Maja Wållberg, Dan Rainbow, Kara Hunter, Linda S Wicker

J Immunol· October 2006

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Type 1 diabetes genes and pathways shared by humans and NOD mice.
Linda S Wicker, Jan Clark, Heather I Fraser, Valerie E S Garner, Andrea Gonzalez-Munoz, Kara Hunter

J Autoimmun· June 2006

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In vivo RNA interference demonstrates a role for Nramp1 in modifying susceptibility to type 1 diabetes.
Stephan Kissler, Patrick Stern, Kazue Takahashi, Kara Hunter, Laurence B Peterson

Nat Genet· April 2006

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Natural genetic variants influencing type 1 diabetes in humans and in the NOD mouse.
Linda S Wicker, Carolyn L Moule, Heather Fraser, Carlos Penha-Goncalves, Dan Rainbow, Kara Hunter

Novartis Found Symp· November 2005

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CD8+ T cell tolerance in nonobese diabetic mice is restored by insulin-dependent diabetes resistance alleles.
Xavier Martinez, Huub T C Kreuwel, William L Redmond, Rebecca Trenney, Kara Hunter

J Immunol· August 2005

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Construction and analysis of tag single nucleotide polymorphism maps for six human-mouse orthologous candidate genes in type 1 diabetes.
Lisa M Maier, Deborah J Smyth, Adrian Vella, Felicity Payne, Jason D Cooper, Kara M Hunter

BMC Genet· February 2005

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Fine mapping, gene content, comparative sequencing, and expression analyses support Ctla4 and Nramp1 as candidates for Idd5.1 and Idd5.2 in the nonobese diabetic mouse.
Linda S Wicker, Giselle Chamberlain, Kara Hunter, Dan Rainbow, Sarah Howlett

J Immunol· July 2004

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Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease.
Hironori Ueda, Joanna M M Howson, Laura Esposito, Joanne Heward, Hywel Snook, Kara M D Hunter

Nature· May 2003

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