Publications by authors named "Kari Gaither"

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Human in vitro metabolism of an environmental mixture of polycyclic aromatic hydrocarbons (PAH) found at the Portland Harbor Superfund Site.
Kari A Gaither, Kimberly Tyrrell, Whitney Garcia, Kim A Anderson, Jordan N Smith

Toxicol Lett· October 2025

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Effects of Chronic Alcohol Intake on the Composition of the Ensemble of Drug-Metabolizing Enzymes and Transporters in the Human Liver.
Kari A Gaither, Guihua Yue, Dilip Kumar Singh, Julia Trudeau, Kannapiran Ponraj

J Xenobiot· January 2025

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Non-additivity of the functional properties of individual P450 species and its manifestation in the effects of alcohol consumption on the metabolism of ketamine and amitriptyline.
Kannapiran Ponraj, Kari A Gaither, Dilip Kumar Singh, Nadezhda Davydova, Mengqi Zhao

Biochem Pharmacol· December 2024

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Activity-Based Protein Profiling to Probe Relationships between Cytochrome P450 Enzymes and Early-Age Metabolism of Two Polycyclic Aromatic Hydrocarbons (PAHs): Phenanthrene and Retene.
Kari A Gaither, Whitney L Garcia, Kimberly J Tyrrell, Aaron T Wright, Jordan N Smith

Chem Res Toxicol· May 2024

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Effects of alcohol consumption and tobacco smoking on the composition of the ensemble of drug metabolizing enzymes and transporters in human liver.
Kari A Gaither, Dilip Kumar Singh, Guihua Yue, Julia Trudeau, Kannapiran Ponraj

bioRxiv· May 2024

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High-Throughput Assay of Cytochrome P450-Dependent Drug Demethylation Reactions and Its Use to Re-Evaluate the Pathways of Ketamine Metabolism.
Nadezhda Y Davydova, David A Hutner, Kari A Gaither, Dilip Kumar Singh, Bhagwat Prasad

Biology (Basel)· July 2023

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Competitive Metabolism of Polycyclic Aromatic Hydrocarbons (PAHs): An Assessment Using In Vitro Metabolism and Physiologically Based Pharmacokinetic (PBPK) Modeling.
Jordan N Smith, Kari A Gaither, Paritosh Pande

Int J Environ Res Public Health· July 2022

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Profiling How the Gut Microbiome Modulates Host Xenobiotic Metabolism in Response to Benzo[]pyrene and 1-Nitropyrene Exposure.
Whitney L Garcia, Carson J Miller, Gerard X Lomas, Kari A Gaither, Kimberly J Tyrrell

Chem Res Toxicol· April 2022

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Expression of activating transcription factor 5 (ATF5) is mediated by microRNA-520b-3p under diverse cellular stress in cancer cells.
Kari A Gaither, Christy J W Watson, Bhanupriya Madarampalli, Philip Lazarus

PLoS One· August 2020

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SUMO2/3 modification of activating transcription factor 5 (ATF5) controls its dynamic translocation at the centrosome.
Yunsheng Yuan, Kari Gaither, Eugene Kim, Edward Liu, Ming Hu

J Biol Chem· February 2018

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The immunomodulatory, antitumor and antimetastatic responses of melanoma-bearing normal and alcoholic mice to sunitinib and ALT-803: a combinatorial treatment approach.
Kari A Gaither, Alexander A Little, Alisha A McBride, Savanna R Garcia, Kiranjot K Brar

Cancer Immunol Immunother· September 2016

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Modification of polyurethane to reduce occlusion of enteral feeding tubes.
Kari A Gaither, Barbara J Tarasevich, Steven C Goheen

J Biomed Mater Res B Appl Biomater· October 2009

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Corona discharge influences ozone concentrations near rats.
Steven C Goheen, Kari Gaither, Shantha M Anantatmula, Gary M Mong, Lyle B Sasser

Bioelectromagnetics· February 2004

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