Publications by authors named "Karim P M Labib"

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USP37 protects mammalian cells during DNA replication stress by counteracting CUL2 and TRAIP.
Fabrizio Villa, Johanna Ainsworth, Karim P M Labib

Cell Rep· June 2025

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CMG helicase disassembly is essential and driven by two pathways in budding yeast.
Cristian Polo Rivera, Tom D Deegan, Karim P M Labib

EMBO J· September 2024

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Mechanism of human PINK1 activation at the TOM complex in a reconstituted system.
Olawale G Raimi, Hina Ojha, Kenneth Ehses, Verena Dederer, Sven M Lange, Karim P M Labib

Sci Adv· June 2024

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DNSN-1 recruits GINS for CMG helicase assembly during DNA replication initiation in .
Yisui Xia, Remi Sonneville, Michael Jenkyn-Bedford, Liqin Ji, Constance Alabert, Karim P M Labib

Science· September 2023

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Multiple UBX proteins reduce the ubiquitin threshold of the mammalian p97-UFD1-NPL4 unfoldase.
Ryo Fujisawa, Cristian Polo Rivera, Karim P M Labib

Elife· August 2022

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Spt5 histone binding activity preserves chromatin during transcription by RNA polymerase II.
Cecile Evrin, Albert Serra-Cardona, Shoufu Duan, Progya P Mukherjee, Zhiguo Zhang, Karim P M Labib

EMBO J· March 2022

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A conserved mechanism for regulating replisome disassembly in eukaryotes.
Michael Jenkyn-Bedford, Morgan L Jones, Yasemin Baris, Karim P M Labib, Giuseppe Cannone

Nature· December 2021

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TIMELESS-TIPIN and UBXN-3 promote replisome disassembly during DNA replication termination in Caenorhabditis elegans.
Yisui Xia, Ryo Fujisawa, Tom D Deegan, Remi Sonneville, Karim P M Labib

EMBO J· September 2021

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Reconstitution of human CMG helicase ubiquitylation by CUL2LRR1 and multiple E2 enzymes.
Thanh Thi Le, Johanna Ainsworth, Cristian Polo Rivera, Thomas Macartney, Karim P M Labib

Biochem J· July 2021

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In Vitro Reconstitution Defines the Minimal Requirements for Cdc48-Dependent Disassembly of the CMG Helicase in Budding Yeast.
Progya P Mukherjee, Karim P M Labib

Cell Rep· September 2019

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Pif1-Family Helicases Support Fork Convergence during DNA Replication Termination in Eukaryotes.
Tom D Deegan, Jonathan Baxter, María Ángeles Ortiz Bazán, Joseph T P Yeeles, Karim P M Labib

Mol Cell· April 2019

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