Publications by authors named "Karin List"

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Development of ketobenzothiazole-based peptidomimetic TMPRSS13 inhibitors with low nanomolar potency.
Alexandre Joushomme, Antoine Désilets, William Champagne, Malihe Hassanzadeh, Gabriel Lemieux, Karin List

J Enzyme Inhib Med Chem· December 2025

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The cell-surface serine protease prostasin is lost during cervical squamous cell carcinogenesis.
Joseph G Lundgren, Michael G Flynn, Karin List

Hum Cell· August 2025

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GPI-anchored serine proteases: essential roles in development, homeostasis, and disease.
Joseph G Lundgren, Michael G Flynn, Karin List

Biol Chem· January 2025

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Development of ketobenzothiazole-based peptidomimetic TMPRSS13 inhibitors with low nanomolar potency.
Alexandre Joushomme, Antoine Désilets, William Champagne, Malihe Hassanzadeh, Gabriel Lemieux, Karin List

bioRxiv· August 2024

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TMPRSS13 zymogen activation, surface localization, and shedding is regulated by proteolytic cleavage within the non-catalytic stem region.
Carly E Martin, Andrew S Murray, Jacob R Mackinder, Kimberley E Sala-Hamrick, Michael G Flynn, Karin List

Biol Chem· September 2022

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Posttranslational modifications of serine protease TMPRSS13 regulate zymogen activation, proteolytic activity, and cell surface localization.
Carly E Martin, Andrew S Murray, Kimberley E Sala-Hamrick, Jacob R Mackinder, Evan C Harrison, Karin List

J Biol Chem· October 2021

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The cell-surface anchored serine protease TMPRSS13 promotes breast cancer progression and resistance to chemotherapy.
Andrew S Murray, Thomas E Hyland, Kimberley E Sala-Hamrick, Jacob R Mackinder, Carly E Martin, Karin List

Oncogene· October 2020

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TMPRSS13 promotes cell survival, invasion, and resistance to drug-induced apoptosis in colorectal cancer.
Fausto A Varela, Victoria L Foust, Thomas E Hyland, Kimberley E Sala-Hamrick, Jacob R Mackinder, Karin List

Sci Rep· August 2020

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Cell surface-anchored serine proteases in cancer progression and metastasis.
Carly E Martin, Karin List

Cancer Metastasis Rev· September 2019

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Phosphorylation of the type II transmembrane serine protease, TMPRSS13, in hepatocyte growth factor activator inhibitor-1 and -2-mediated cell-surface localization.
Andrew S Murray, Fausto A Varela, Thomas E Hyland, Andrew J Schoenbeck, Jordan M White, Karin List

J Biol Chem· September 2017

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The role of type II transmembrane serine protease-mediated signaling in cancer.
Lauren M Tanabe, Karin List

FEBS J· May 2017

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Type II transmembrane serine proteases as potential targets for cancer therapy.
Andrew S Murray, Fausto A Varela, Karin List

Biol Chem· September 2016

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Matriptase regulates c-Met mediated proliferation and invasion in inflammatory breast cancer.
Gina L Zoratti, Lauren M Tanabe, Thomas E Hyland, Michael J Duhaime, Éloïc Colombo, Karin List

Oncotarget· September 2016

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Cell Surface Human Airway Trypsin-Like Protease Is Lost During Squamous Cell Carcinogenesis.
Michael J Duhaime, Khaliph O Page, Fausto A Varela, Andrew S Murray, Michael E Silverman, Karin List

J Cell Physiol· July 2016

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Targeting matriptase in breast cancer abrogates tumour progression via impairment of stromal-epithelial growth factor signalling.
Gina L Zoratti, Lauren M Tanabe, Fausto A Varela, Andrew S Murray, Christopher Bergum, Karin List

Nat Commun· April 2015

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HATL5: a cell surface serine protease differentially expressed in epithelial cancers.
Gregory S Miller, Gina L Zoratti, Andrew S Murray, Christopher Bergum, Lauren M Tanabe, Karin List

PLoS One· December 2014

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The matriptase-prostasin proteolytic cascade in epithelial development and pathology.
Gregory S Miller, Karin List

Cell Tissue Res· February 2013

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Fibroblast-secreted hepatocyte growth factor mediates epidermal growth factor receptor tyrosine kinase inhibitor resistance in triple-negative breast cancers through paracrine activation of Met.
Kelly L Mueller, Julie M Madden, Gina L Zoratti, Charlotte Kuperwasser, Karin List

Breast Cancer Res· July 2012

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Strong expression association between matriptase and its substrate prostasin in breast cancer.
Christopher Bergum, Gina Zoratti, Julie Boerner, Karin List

J Cell Physiol· April 2012

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Loss of the matriptase inhibitor HAI-2 during prostate cancer progression.
Christopher Bergum, Karin List

Prostate· September 2010

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Matriptase initiates activation of epidermal pro-kallikrein and disease onset in a mouse model of Netherton syndrome.
Katiuchia Uzzun Sales, Andrius Masedunskas, Alexandra L Bey, Amber L Rasmussen, Roberto Weigert, Karin List

Nat Genet· August 2010

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Membrane-anchored serine protease matriptase regulates epithelial barrier formation and permeability in the intestine.
Marguerite S Buzza, Sarah Netzel-Arnett, Terez Shea-Donohue, Aiping Zhao, Chen-Yong Lin, Karin List

Proc Natl Acad Sci U S A· March 2010

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Epithelial integrity is maintained by a matriptase-dependent proteolytic pathway.
Karin List, Peter Kosa, Roman Szabo, Alexandra L Bey, Chao Becky Wang

Am J Pathol· October 2009

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Regulation of cell surface protease matriptase by HAI2 is essential for placental development, neural tube closure and embryonic survival in mice.
Roman Szabo, John P Hobson, Kristina Christoph, Peter Kosa, Karin List

Development· August 2009

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Loss of matriptase suppression underlies spint1 mutation-associated ichthyosis and postnatal lethality.
Roman Szabo, Peter Kosa, Karin List, Thomas H Bugge

Am J Pathol· June 2009

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