Publications by authors named "Karl Aston"

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β-Alanine and N-terminal cationic substituents affect polyamide-DNA binding.
Beibei Liu, Shuo Wang, Karl Aston, Kevin J Koeller, Shahrzad Fanny Hakami Kermani

Org Biomol Chem· November 2017

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Modulation of DNA-polyamide interaction by β-alanine substitutions: a study of positional effects on binding affinity, kinetics and thermodynamics.
Shuo Wang, Karl Aston, Kevin J Koeller, G Davis Harris, Nigam P Rath

Org Biomol Chem· October 2014

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DNA Binding Polyamides and the Importance of DNA Recognition in their use as Gene-Specific and Antiviral Agents.
Kevin J Koeller, G Davis Harris, Karl Aston, Gaofei He, Carlos H Castaneda

Med Chem (Los Angeles)· February 2014

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Different thermodynamic signatures for DNA minor groove binding with changes in salt concentration and temperature.
Shuo Wang, Arvind Kumar, Karl Aston, Binh Nguyen, James K Bashkin

Chem Commun (Camb)· October 2013

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Promoter scanning of the human COX-2 gene with 8-ring polyamides: unexpected weakening of polyamide-DNA binding and selectivity by replacing an internal N-Me-pyrrole with β-alanine.
James K Bashkin, Karl Aston, Joseph P Ramos, Kevin J Koeller, Rupesh Nanjunda

Biochimie· February 2013

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Correlation of local effects of DNA sequence and position of β-alanine inserts with polyamide-DNA complex binding affinities and kinetics.
Shuo Wang, Rupesh Nanjunda, Karl Aston, James K Bashkin, W David Wilson

Biochemistry· December 2012

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Fluorescence assay of polyamide-DNA interactions.
Cynthia M Dupureur, James K Bashkin, Karl Aston, Kevin J Koeller, Kimberly R Gaston

Anal Biochem· April 2012

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The novel benzopyran class of selective cyclooxygenase-2 inhibitors. Part III: the three microdose candidates.
Jane L Wang, Karl Aston, David Limburg, Cindy Ludwig, Ann E Hallinan

Bioorg Med Chem Lett· December 2010

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Discovery of (pyridin-4-yl)-2H-tetrazole as a novel scaffold to identify highly selective matrix metalloproteinase-13 inhibitors for the treatment of osteoarthritis.
Mark E Schnute, Patrick M O'Brien, Joe Nahra, Mark Morris, W Howard Roark, Karl W Aston

Bioorg Med Chem Lett· January 2010

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Computer-Aided Design (CAD) of Synzymes: Use of Molecular Mechanics (MM) for the Rational Design of Superoxide Dismutase Mimics.
Dennis P. Riley, Susan L. Henke, Patrick J. Lennon, Karl Aston

Inorg Chem· April 1999

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