Publications by authors named "Karl Frank"

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Structure-based characterization of multiprotein complexes.
Markus Wiederstein, Markus Gruber, Karl Frank, Francisco Melo, Manfred J Sippl

Structure· July 2014

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Benzazepinones and benzoxazepinones as antagonists of inhibitor of apoptosis proteins (IAPs) selective for the second baculovirus IAP repeat (BIR2) domain.
Andrew F Donnell, Christophe Michoud, Kenneth C Rupert, Xiaochun Han, Douglas Aguilar, Karl B Frank

J Med Chem· October 2013

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Identification of N-acyl 4-(3-pyridonyl)phenylalanine derivatives and their orally active prodrug esters as dual acting α4β1 and α4β7 receptor antagonists.
Jefferson W Tilley, Achyutharao Sidduri, Jianping Lou, Gerry Kaplan, Nadine Tare, Karl Frank

Bioorg Med Chem Lett· February 2013

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Identification of N-acyl 4-(5-pyrimidine-2,4-dionyl)phenylalanine derivatives and their orally active prodrug esters as dual-acting alpha4-beta1 and alpha4-beta7 receptor antagonists.
Achyutharao Sidduri, Jefferson W Tilley, Jianping Lou, Nadine Tare, Gary Cavallo, Karl Frank

Bioorg Med Chem Lett· February 2013

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3-Amido pyrrolopyrazine JAK kinase inhibitors: development of a JAK3 vs JAK1 selective inhibitor and evaluation in cellular and in vivo models.
Michael Soth, Johannes C Hermann, Calvin Yee, Muzaffar Alam, Jim W Barnett, Karl Frank

J Med Chem· January 2013

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Pharmacokinetic/Pharmacodynamic predictors of clinical potency for hepatitis C virus nonnucleoside polymerase and protease inhibitors.
Micaela B Reddy, Peter N Morcos, Sophie Le Pogam, Ying Ou, Karl Frank

Antimicrob Agents Chemother· June 2012

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COPS benchmark: interactive analysis of database search methods.
Karl Frank, Markus Gruber, Manfred J Sippl

Bioinformatics· February 2010

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High-performance signal peptide prediction based on sequence alignment techniques.
Karl Frank, Manfred J Sippl

Bioinformatics· October 2008

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Temporal gene expression profiling indicates early up-regulation of interleukin-6 in isoproterenol-induced myocardial necrosis in rat.
Igor Mikaelian, Denise Coluccio, Kevin T Morgan, Teona Johnson, Amber L Ryan, Karl Frank

Toxicol Pathol· February 2008

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Evaluation of the effect of multiple-dose administration of R411, a dual alpha4beta1-alpha4beta7 integrin antagonist on the major CYP isoform activities in healthy volunteers.
Youssef Hijazi, Horst Welker, Albert E Dorr, Karl Frank, Louis M Renzetti

Eur J Clin Pharmacol· January 2006

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