Publications by authors named "Karl Frei"

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Single-cell atlas of the human brain vasculature across development, adulthood and disease.
Thomas Wälchli, Moheb Ghobrial, Marc Schwab, Shigeki Takada, Hang Zhong, Karl Frei

Nature· August 2024

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Nucleolin promotes angiogenesis and endothelial metabolism along the oncofetal axis in the human brain vasculature.
Marc Schwab, Ignazio de Trizio, Moheb Ghobrial, Jau-Ye Shiu, Oguzkan Sürücü, Karl Frei

JCI Insight· April 2023

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Republication: Targeting PI3KC2β Impairs Proliferation and Survival in Acute Leukemia, Brain Tumours and Neuroendocrine Tumours.
Danielle Boller, Kathrin T Doepfner, Angela DE Laurentiis, Ana S Guerreiro, Marin Marinov, Karl Frei

Anticancer Res· June 2022

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Tunneling nanotubes evoke pericyte/endothelial communication during normal and tumoral angiogenesis.
Mariella Errede, Domenica Mangieri, Giovanna Longo, Francesco Girolamo, Ignazio de Trizio, Karl Frei

Fluids Barriers CNS· October 2018

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Age-associated and therapy-induced alterations in the cellular microenvironment of experimental gliomas.
Hannah Schneider, Birthe Lohmann, Hans-Georg Wirsching, Kathy Hasenbach, Elisabeth J Rushing, Karl Frei

Oncotarget· October 2017

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Interleukin-33 in human gliomas: Expression and prognostic significance.
Dorothee Gramatzki, Karl Frei, Gieri Cathomas, Holger Moch, Michael Weller

Oncol Lett· July 2016

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Modulation of cerebral endothelial cell function by TGF-β in glioblastoma: VEGF-dependent angiogenesis versus endothelial mesenchymal transition.
Shanmugarajan Krishnan, Emese Szabo, Isabel Burghardt, Karl Frei, Ghazaleh Tabatabai

Oncotarget· September 2015

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Wiring the Vascular Network with Neural Cues: A CNS Perspective.
Thomas Wälchli, Andrin Wacker, Karl Frei, Luca Regli, Martin E Schwab

Neuron· July 2015

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Targeting class IA PI3K isoforms selectively impairs cell growth, survival, and migration in glioblastoma.
Katrin Höland, Danielle Boller, Christian Hagel, Silvia Dolski, András Treszl, Karl Frei

PLoS One· June 2015

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Transforming growth factor-β pathway activity in glioblastoma.
Karl Frei, Dorothee Gramatzki, Isabel Tritschler, Judith Johanna Schroeder, Larisa Espinoza

Oncotarget· March 2015

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Diversified expression of NG2/CSPG4 isoforms in glioblastoma and human foetal brain identifies pericyte subsets.
Francesco Girolamo, Alice Dallatomasina, Marco Rizzi, Mariella Errede, Thomas Wälchli, Karl Frei

PLoS One· February 2015

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How stemlike are sphere cultures from long-term cancer cell lines? Lessons from mouse glioma models.
Mushfika Ahmad, Karl Frei, Edith Willscher, Anja Stefanski, Kerstin Kaulich

J Neuropathol Exp Neurol· November 2014

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Redox-directed cancer therapeutics: Taurolidine and Piperlongumine as broadly effective antineoplastic agents (review).
Hanns Möhler, Rolf W Pfirrmann, Karl Frei

Int J Oncol· October 2014

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Bleeding propensity of cavernous malformations: impact of tight junction alterations on the occurrence of overt hematoma.
Dejan Jakimovski, Hannah Schneider, Karl Frei, Lieven N Kennes, Helmut Bertalanffy

J Neurosurg· September 2014

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Interferon-β induces loss of spherogenicity and overcomes therapy resistance of glioblastoma stem cells.
Caroline Happold, Patrick Roth, Manuela Silginer, Ana-Maria Florea, Katrin Lamszus, Karl Frei

Mol Cancer Ther· April 2014

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Thymosin β 4 gene silencing decreases stemness and invasiveness in glioblastoma.
Hans-Georg Wirsching, Shanmugarajan Krishnan, Ana-Maria Florea, Karl Frei, Niklaus Krayenbühl

Brain· February 2014

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The CXCL12/CXCR4/CXCR7 ligand-receptor system regulates neuro-glio-vascular interactions and vessel growth during human brain development.
Daniela Virgintino, Mariella Errede, Marco Rizzi, Francesco Girolamo, Maurizio Strippoli, Karl Frei

J Inherit Metab Dis· May 2013

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Nogo-A is a negative regulator of CNS angiogenesis.
Thomas Wälchli, Vincent Pernet, Oliver Weinmann, Jau-Ye Shiu, Anna Guzik-Kornacka, Karl Frei

Proc Natl Acad Sci U S A· May 2013

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Soluble α-klotho: a novel serum biomarker for the activity of GH-producing pituitary adenomas.
Marian Christoph Neidert, Lisa Sze, Cornelia Zwimpfer, Johannes Sarnthein, Burkhardt Seifert, Karl Frei

Eur J Endocrinol· April 2013

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Stroma-derived interleukin-34 controls the development and maintenance of langerhans cells and the maintenance of microglia.
Melanie Greter, Iva Lelios, Pawel Pelczar, Guillaume Hoeffel, Jeremy Price, Karl Frei

Immunity· December 2012

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Patupilone (epothilone B) for recurrent glioblastoma: clinical outcome and translational analysis of a single-institution phase I/II trial.
Christoph Oehler, Karl Frei, Elisabeth J Rushing, Paul M J McSheehy, Dirk Weber

Oncology· October 2012

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Proteomic analysis reveals drug accessible cell surface N-glycoproteins of primary and established glioblastoma cell lines.
Thomas Bock, Hansjoerg Moest, Ulrich Omasits, Silvia Dolski, Emma Lundberg, Andreas Frei, Karl Frei

J Proteome Res· October 2012

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Targeting PI3KC2β impairs proliferation and survival in acute leukemia, brain tumours and neuroendocrine tumours.
Danielle Boller, Kathrin T Doepfner, Angela De Laurentiis, Ana S Guerreiro, Marin Marinov, Karl Frei

Anticancer Res· August 2012

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Adoptive transfer of T lymphocytes in immunodeficient mice influences epileptogenesis and neurodegeneration in a model of temporal lobe epilepsy.
Francine Deprez, Michela Zattoni, Maria Luisa Mura, Karl Frei, Jean-Marc Fritschy

Neurobiol Dis· November 2011

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The microtubule stabilizer patupilone (epothilone B) is a potent radiosensitizer in medulloblastoma cells.
Christoph Oehler, André O von Bueren, Polina Furmanova, Angela Broggini-Tenzer, Katrin Orlowski, Karl Frei

Neuro Oncol· September 2011

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