Publications by authors named "Karsten Sauer"

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Intratumoral injection and retention hold promise to improve cytokine therapies for cancer.
Karsten Sauer, Kavya Rakhra, Kaida Wu, Naveen K Mehta, Jennifer S Michaelson

Front Oncol· August 2024

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Cell surface-tethered IL-12 repolarizes the tumor immune microenvironment to enhance the efficacy of adoptive T cell therapy.
Douglas S Jones, Jonathan D Nardozzi, Katharine L Sackton, Gulzar Ahmad, Esben Christensen, Karsten Sauer

Sci Adv· April 2022

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Allelic variation in class I HLA determines CD8 T cell repertoire shape and cross-reactive memory responses to SARS-CoV-2.
Joshua M Francis, Del Leistritz-Edwards, Augustine Dunn, Christina Tarr, Jesse Lehman, Karsten Sauer

Sci Immunol· January 2022

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Are T cell repertoires useful as diagnostics for SARS- CoV- 2 infection?
Tim Harris, Karsten Sauer

Expert Rev Mol Diagn· February 2021

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An Effective COVID-19 Vaccine Needs to Engage T Cells.
Karsten Sauer, Tim Harris

Front Immunol· November 2020

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Regulation of Hematopoietic Cell Development and Function Through Phosphoinositides.
Mila Elich, Karsten Sauer

Front Immunol· July 2019

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CRISPR-Cas9-Mediated Modification of the NOD Mouse Genome With Ptpn22R619W Mutation Increases Autoimmune Diabetes.
Xiaotian Lin, Stephane Pelletier, Sebastien Gingras, Stephanie Rigaud, Christian J Maine, Karsten Sauer

Diabetes· August 2016

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hCD2-iCre and Vav-iCre mediated gene recombination patterns in murine hematopoietic cells.
Sabine Siegemund, Jovan Shepherd, Changchun Xiao, Karsten Sauer

PLoS One· April 2016

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Non-canonical antagonism of PI3K by the kinase Itpkb delays thymocyte β-selection and renders it Notch-dependent.
Luise Westernberg, Claire Conche, Yina Hsing Huang, Stephanie Rigaud, Yisong Deng, Karsten Sauer

Elife· February 2016

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Mst1 directs Myosin IIa partitioning of low and higher affinity integrins during T cell migration.
Xiaolu Xu, Emily R Jaeger, Xinxin Wang, Erica Lagler-Ferrez, Serge Batalov, Karsten Sauer

PLoS One· December 2015

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Interleukin-7 is required for CD4(+) T cell activation and autoimmune neuroinflammation.
Brian R Lawson, Rosana Gonzalez-Quintial, Theodoros Eleftheriadis, Michael A Farrar, Stephen D Miller, Karsten Sauer

Clin Immunol· December 2015

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Agonist antibody that induces human malignant cells to kill one another.
Kyungmoo Yea, Hongkai Zhang, Jia Xie, Teresa M Jones, Chih-Wei Lin, Karsten Sauer

Proc Natl Acad Sci U S A· November 2015

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Allelic exclusion of TCR α-chains upon severe restriction of Vα repertoire.
Vasily Rybakin, Luise Westernberg, Guo Fu, Hee-Ok Kim, Jeanette Ampudia, Karsten Sauer

PLoS One· October 2015

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Editorial: Lipid Signaling in T Cell Development and Function.
Karsten Sauer, Klaus Okkenhaug

Front Immunol· August 2015

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IP3 3-kinase B prevents bone marrow failure.
Stephanie Rigaud, Karsten Sauer

Oncotarget· June 2015

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IP3 3-kinase B controls hematopoietic stem cell homeostasis and prevents lethal hematopoietic failure in mice.
Sabine Siegemund, Stephanie Rigaud, Claire Conche, Blake Broaten, Lana Schaffer, Karsten Sauer

Blood· April 2015

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Uncovering the PI3Ksome: phosphoinositide 3-kinases and counteracting PTEN form a signaling complex with intrinsic regulatory properties.
Claire Conche, Karsten Sauer

Mol Cell Biol· September 2014

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In silico modeling of Itk activation kinetics in thymocytes suggests competing positive and negative IP4 mediated feedbacks increase robustness.
Sayak Mukherjee, Stephanie Rigaud, Sang-Cheol Seok, Guo Fu, Agnieszka Prochenka, Karsten Sauer

PLoS One· May 2014

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Themis sets the signal threshold for positive and negative selection in T-cell development.
Guo Fu, Javier Casas, Stephanie Rigaud, Vasily Rybakin, Florence Lambolez, Karsten Sauer

Nature· December 2013

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A conserved motif in the ITK PH-domain is required for phosphoinositide binding and TCR signaling but dispensable for adaptor protein interactions.
Nupura Hirve, Roman M Levytskyy, Stephanie Rigaud, David M Guimond, Tomasz Zal, Karsten Sauer

PLoS One· February 2013

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Inositol tetrakisphosphate limits NK cell effector functions by controlling PI3K signaling.
Karsten Sauer, Eugene Park, Sabine Siegemund, Anthony R French, Joseph A Wahle

Blood· January 2013

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Balancing pro- and anti-inflammatory TLR4 signaling.
Sabine Siegemund, Karsten Sauer

Nat Immunol· November 2012

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Protein kinase C η is required for T cell activation and homeostatic proliferation.
Guo Fu, Jianfang Hu, Nathalie Niederberger-Magnenat, Vasily Rybakin, Javier Casas, Karsten Sauer

Sci Signal· December 2011

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Mechanisms of drug resistance in kinases.
Rina Barouch-Bentov, Karsten Sauer

Expert Opin Investig Drugs· February 2011

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Lipid signaling in T-cell development and function.
Yina H Huang, Karsten Sauer

Cold Spring Harb Perspect Biol· November 2010

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