Publications by authors named "Karsten Siems"

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Optimization of Biocatalytic Rhododendrol Production from Biogenic Rhododendrol Glycosides.
Emerik Leaković, Karsten Siems, Michel Feussi Tala, Antonia Habazin, Zvjezdana Findrik Blažević

ACS Sustain Chem Eng· November 2024

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Western diet-induced cognitive and metabolic dysfunctions in aged mice are prevented by rosmarinic acid in a sex-dependent fashion.
Letizia Giona, Chiara Musillo, Gaia De Cristofaro, Michael Ristow, Kim Zarse, Karsten Siems

Clin Nutr· October 2024

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Rosmarinic Acid Improves Cognitive Abilities and Glucose Metabolism in Aged C57Bl/6N Mice While Disrupting Lipid Profile in Young Adults in a Sex-Dependent Fashion.
Chiara Musillo, Letizia Giona, Michael Ristow, Kim Zarse, Karsten Siems

Nutrients· July 2023

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Identification of a Hydroxygallic Acid Derivative, Zingibroside R1 and a Sterol Lipid as Potential Active Ingredients of Extract That Has Neuroprotective and Antioxidant Effects in Aged .
Shimaa M A Sayed, Saleh Alseekh, Karsten Siems, Alisdair R Fernie, Walter Luyten

Nutrients· October 2022

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Ion-Pairing Chromatography and Amine Derivatization Provide Complementary Approaches for the Targeted LC-MS Analysis of the Polar Metabolome.
Virag Sagi-Kiss, Yufeng Li, Matthew R Carey, Sarah J Grover, Karsten Siems

J Proteome Res· June 2022

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Novel mannosylerythritol lipid biosurfactant structures from castor oil revealed by advanced structure analysis.
Alexander Beck, Fabian Haitz, Isabel Thier, Karsten Siems, Sven Jakupovic

J Ind Microbiol Biotechnol· August 2021

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An ADH toolbox for raspberry ketone production from natural resources via a biocatalytic cascade.
Aileen Becker, Dominique Böttcher, Werner Katzer, Karsten Siems, Lutz Müller-Kuhrt

Appl Microbiol Biotechnol· May 2021

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Enhanced Healthspan in Treated With Extracts From the Traditional Chinese Medicine Plants Lam. and Oliv.
Shimaa M A Sayed, Karsten Siems, Christian Schmitz-Linneweber, Walter Luyten, Nadine Saul

Front Pharmacol· February 2021

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Intense bitterness of molecules: Machine learning for expediting drug discovery.
Eitan Margulis, Ayana Dagan-Wiener, Robert S Ives, Sara Jaffari, Karsten Siems

Comput Struct Biotechnol J· December 2020

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Plant-Derived Molecules α-Boswellic Acid Acetate, Praeruptorin-A, and Salvianolic Acid-B Have Age-Related Differential Effects in Young and Senescent Human Fibroblasts In Vitro.
Anna Lewinska, Lakshman Sodagam, Dominika Bloniarz, Karsten Siems, Maciej Wnuk

Molecules· December 2019

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Phytochemicals Rosmarinic Acid, Ampelopsin, and Amorfrutin-A Can Modulate Age-Related Phenotype of Serially Passaged Human Skin Fibroblasts .
Lakshman Sodagam, Anna Lewinska, Ewa Kwasniewicz, Sofiya Kokhanovska, Maciej Wnuk, Karsten Siems

Front Genet· February 2019

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Tonantzitlolone is a nanomolar potency activator of transient receptor potential canonical 1/4/5 channels.
Hussein N Rubaiy, Melanie J Ludlow, Karsten Siems, Katherine Norman, Richard Foster

Br J Pharmacol· August 2018

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Natural 6-hydroxy-chromanols and -chromenols: structural diversity, biosynthetic pathways and health implications.
Marc Birringer, Karsten Siems, Alexander Maxones, Jan Frank, Stefan Lorkowski

RSC Adv· January 2018

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Long-Lasting WNT-TCF Response Blocking and Epigenetic Modifying Activities of Withanolide F in Human Cancer Cells.
Chandan Seth, Christophe Mas, Arwen Conod, Jens Mueller, Karsten Siems

PLoS One· July 2017

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Effects of extracts and compounds from Tricholoma populinum Lange on degranulation and IL-2/IL-8 secretion of immune cells.
Simon Merdivan, Kristina Jenett-Siems, Karsten Siems, Timo H J Niedermeyer, Nadin Schultze

Z Naturforsch C J Biosci· July 2017

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Flavonol Glycosides and Cytotoxic Steroidal Saponins from Furcraea tuberosa (Agavaceae).
Leon A Tapondjou, Kristina Jenett-Siems, Karsten Siems, Alexander Weng, Matthias F Melzig

Nat Prod Commun· March 2017

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Sesquiterpene Lactone Composition and Cellular Nrf2 Induction of Taraxacum officinale Leaves and Roots and Taraxinic Acid β-d-Glucopyranosyl Ester.
Tuba Esatbeyoglu, Betina Obermair, Tabea Dorn, Karsten Siems, Gerald Rimbach

J Med Food· January 2017

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Synthesis and antiproliferative activity of new tonantzitlolone-derived diterpene derivatives.
Torsten Busch, Gerald Dräger, Eike Kunst, Hannah Benson, Florenz Sasse, Karsten Siems

Org Biomol Chem· October 2016

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Ageing with elegans: a research proposal to map healthspan pathways.
Walter Luyten, Peter Antal, Bart P Braeckman, Jake Bundy, Francesca Cirulli, Karsten Siems

Biogerontology· August 2016

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Amorfrutin C Induces Apoptosis and Inhibits Proliferation in Colon Cancer Cells through Targeting Mitochondria.
Christopher Weidner, Morten Rousseau, Robert J Micikas, Cornelius Fischer, Annabell Plauth, Karsten Siems

J Nat Prod· January 2016

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Tonantzitlolone cytotoxicity toward renal cancer cells is PKCθ- and HSF1-dependent.
Carole Sourbier, Bradley T Scroggins, Philip Z Mannes, Pei-Jyun Liao, Karsten Siems

Oncotarget· October 2015

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Cytotoxic saponins from the seeds of Pittosporum angustifolium.
Christian Bäcker, Kristina Jenett-Siems, Karsten Siems, Martina Wurster, Anja Bodtke

Z Naturforsch C J Biosci· August 2014

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Protein kinase and HDAC inhibitors from the endophytic fungus Epicoccum nigrum.
Mustapha El Amrani, Daowan Lai, Abdessamad Debbab, Amal H Aly, Karsten Siems

J Nat Prod· January 2014

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Structure-activity relationships of saponins enhancing the cytotoxicity of ribosome-inactivating proteins type I (RIP-I).
Stefan Böttger, Elena Westhof, Karsten Siems, Matthias F Melzig

Toxicon· October 2013

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Triterpene glycosides from the leaves of Pittosporum angustifolium.
Christian Bäcker, Kristina Jenett-Siems, Karsten Siems, Martina Wurster, Anja Bodtke

Planta Med· October 2013

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