Publications by authors named "Kashish Chetal"

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Transcription factors operate across disease loci, with EBNA2 implicated in autoimmunity.
John B Harley, Xiaoting Chen, Mario Pujato, Daniel Miller, Avery Maddox, Carmy Forney, Albert F Magnusen, Arthur Lynch, Kashish Chetal, Masashi Yukawa

May 2018

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Adeno-associated Virus-mediated Silencing of Sox4 Leads to Long-Term Amelioration of Liver Phenotypes in Mouse Models of Alagille Syndrome.
Duncan Fox, Jun Xie, Jennifer L Burwinkel, Josh M Adams, Kashish Chetal

Gastroenterology· October 2025

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Epigenomic dynamics of clonal evolution reveal new regulators of leukemic growth.
Gracia Bonilla, Alexander Morris, Sharmistha Kundu, Anthony DuCasse, Grace Kirkpatrick, Kashish Chetal

bioRxiv· May 2025

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Splicing regulatory dynamics for precision analysis and treatment of heterogeneous leukemias.
Meenakshi Venkatasubramanian, Leya Schwartz, Nandini Ramachandra, Joshua Bennett, Krithika R Subramanian, Kashish Chetal

Sci Transl Med· May 2025

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Decreased SynMuv B gene activity in response to viral infection leads to activation of the antiviral RNAi pathway in C. elegans.
Ashwin Seetharaman, Himani Galagali, Elizabeth Linarte, Mona H X Liu, Jennifer D Cohen, Kashish Chetal

PLoS Biol· January 2025

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Multi-omics approaches reveal that diffuse midline gliomas present altered DNA replication and are susceptible to replication stress therapy.
Anastasia E Hains, Kashish Chetal, Tsunetoshi Nakatani, Joana G Marques, Andreas Ettinger

Genome Biol· December 2024

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Deferasirox, an iron chelator, impacts myeloid differentiation by modulating NF-kB activity via mitochondrial ROS.
Nathan E Jeffries, Daniel Sadreyev, Elizabeth C Trull, Kashish Chetal, Emma E Yvanovich

Br J Haematol· November 2024

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An Adipo-Pulmonary Axis Mediated by FABP4 Hormone Defines a Therapeutic Target Against Obesity-Induced Airway Disease.
M Furkan Burak, Gurol Tuncman, Ayse Nur Ayci, Kashish Chetal, Grace Yankun Lee Seropian

bioRxiv· July 2024

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SynMuv B gene activity is down-regulated during a viral infection to enhance RNA interference.
Ashwin Seetharaman, Himani Galagali, Elizabeth Linarte, Mona H X Liu, Jennifer D Cohen, Kashish Chetal

bioRxiv· July 2024

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Temporal dynamics and genomic programming of plasma cell fates.
Godhev Kumar Manakkat Vijay, Ming Zhou, Kairavee Thakkar, Abigail Rothrauff, Amanpreet Singh Chawla, Kashish Chetal

Nat Immunol· June 2024

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Broad de-regulated U2AF1 splicing is prognostic and augments leukemic transformation via protein arginine methyltransferase activation.
Meenakshi Venkatasubramanian, Leya Schwartz, Nandini Ramachandra, Joshua Bennett, Krithika R Subramanian, Kashish Chetal

bioRxiv· February 2024

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Population-level single-cell genomics reveals conserved gene programs in systemic juvenile idiopathic arthritis.
Emely L Verweyen, Kairavee Thakkar, Sanjeev Dhakal, Elizabeth Baker, Kashish Chetal

J Clin Invest· November 2023

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Epigenetic balance ensures mechanistic control of MLL amplification and rearrangement.
Zach H Gray, Damayanti Chakraborty, Reuben R Duttweiler, Gulnaz D Alekbaeva, Sedona E Murphy, Kashish Chetal

Cell· October 2023

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Intragraft B cell differentiation during the development of tolerance to kidney allografts is associated with a regulatory B cell signature revealed by single cell transcriptomics.
Michael Tyler Guinn, Edward S Szuter, Takahiro Yokose, Jifu Ge, Ivy A Rosales, Kashish Chetal

Am J Transplant· September 2023

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Mast cell deficiency improves cognition and enhances disease-associated microglia in 5XFAD mice.
Chih-Chung Jerry Lin, Fanny Herisson, Hoang Le, Nader Jaafar, Kashish Chetal

Cell Rep· September 2023

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Temporal dynamics and genomic programming of plasma cell fates.
Godhev Kumar Manakkat Vijay, Ming Zhou, Kairavee Thakkar, Abigail Rothrauff, Amanpreet Singh Chawla, Kashish Chetal

Res Sq· September 2023

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ThPOK is a critical multifaceted regulator of myeloid lineage development.
Jayati Basu, Andre Olsson, Kyle Ferchen, Elizaveta K Titerina, Kashish Chetal

Nat Immunol· August 2023

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Stiffness Restricts the Stemness of the Intestinal Stem Cells and Skews Their Differentiation Toward Goblet Cells.
Shijie He, Peng Lei, Wenying Kang, Priscilla Cheung, Tao Xu, Kashish Chetal

Gastroenterology· June 2023

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Monocytes re-enter the bone marrow during fasting and alter the host response to infection.
Henrike Janssen, Florian Kahles, Dan Liu, Jeffrey Downey, Laura L Koekkoek, Kashish Chetal

Immunity· April 2023

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Ontogeny and function of the circadian clock in intestinal organoids.
Andrew E Rosselot, Miri Park, Mari Kim, Toru Matsu-Ura, Gang Wu, Kashish Chetal

EMBO J· December 2022

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Erythroblastic islands foster granulopoiesis in parallel to terminal erythropoiesis.
Laurel Romano, Katie G Seu, Julien Papoin, David E Muench, Diamantis Konstantinidis, Kashish Chetal

Blood· October 2022

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Fetal maturation revealed by amniotic fluid cell-free transcriptome in rhesus macaques.
Augusto F Schmidt, Daniel J Schnell, Kenneth P Eaton, Kashish Chetal, Paranthaman S Kannan

JCI Insight· September 2022

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Brain motor and fear circuits regulate leukocytes during acute stress.
Wolfram C Poller, Jeffrey Downey, Agnes A Mooslechner, Nargis Khan, Long Li, Kashish Chetal

Nature· July 2022

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A potent myeloid response is rapidly activated in the lungs of premature Rhesus macaques exposed to intra-uterine inflammation.
Courtney M Jackson, Martin Demmert, Shibabrata Mukherjee, Travis Isaacs, Ravyn Thompson, Kashish Chetal

Mucosal Immunol· April 2022

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Inflammatory blockade prevents injury to the developing pulmonary gas exchange surface in preterm primates.
Andrea Toth, Shelby Steinmeyer, Paranthaman Kannan, Jerilyn Gray, Courtney M Jackson, Kashish Chetal

Sci Transl Med· March 2022

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Gain-of-function cardiomyopathic mutations in RBM20 rewire splicing regulation and re-distribute ribonucleoprotein granules within processing bodies.
Aidan M Fenix, Yuichiro Miyaoka, Alessandro Bertero, Steven M Blue, Matthew J Spindler, Kashish Chetal

Nat Commun· November 2021

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