Publications by authors named "Kasper D Rand"

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Development of a Thiol-ene Microfluidic Chip for Hydrogen/Deuterium Exchange Mass Spectrometry (HDX-MS).
Anton B Hansen, Rasmus R Svejdal, Jordan T Aerts, Vanessa B P Stahlhut, Daria Harmash, Kasper D Rand

Anal Chem· June 2025

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Identification of a direct interaction between the Fab domains of IgG antibodies and human FcRn upon IgG-FcRn complex formation.
Esben Trabjerg, Jeannette Nilsen, Torleif Tollefsrud Gjølberg, Jan Terje Andersen, Alexander Leitner, Kasper D Rand

Commun Biol· June 2025

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Structure and dynamics of GAD65 in complex with an autoimmune polyendocrine syndrome type 2-associated autoantibody.
Susanne H D Ständer, Cyril F Reboul, Sarah N Le, Daniel E Williams, Peter G Chandler, Kasper D Rand

Nat Commun· March 2025

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Epitope Mapping of Human Polyclonal Antibodies to the fHbp Antigen of a Neisseria Meningitidis Vaccine by Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS).
Laura R Grauslund, Susanne Ständer, Daniele Veggi, Emanuele Andreano, Kasper D Rand

Mol Cell Proteomics· March 2024

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Development of a PNGase Rc Column for Online Deglycosylation of Complex Glycoproteins during HDX-MS.
Thomas Lambert, Marius Gramlich, Luisa Stutzke, Luke Smith, Dingyu Deng, Kasper D Rand

J Am Soc Mass Spectrom· November 2023

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Conformationally Restricted Glycopeptide Backbone Inhibits Gas-Phase H/D Scrambling between Glycan and Peptide Moieties.
Christian Code, Danwen Qiu, Ilia A Solov'yov, Jung-Goo Lee, Hyeon-Cheol Shin, Kasper D Rand

J Am Chem Soc· November 2023

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PNGase H + variant from Rudaea cellulosilytica with improved deglycosylation efficiency for rapid analysis of eukaryotic N-glycans and hydrogen deuterium exchange mass spectrometry analysis of glycoproteins.
Rui-Rui Guo, Tian-Chan Zhang, Thomas Ole Tandrup Lambert, Ting Wang, Josef Voglmeir, Kasper D Rand

Rapid Commun Mass Spectrom· November 2022

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The dopamine transporter antiports potassium to increase the uptake of dopamine.
Solveig G Schmidt, Mette Galsgaard Malle, Anne Kathrine Nielsen, Søren S-R Bohr, Ciara F Pugh, Kasper D Rand

Nat Commun· May 2022

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Revealing the Dynamic Allosteric Changes Required for Formation of the Cysteine Synthase Complex by Hydrogen-Deuterium Exchange MS.
Brenda Rosa, Eleanor R Dickinson, Marialaura Marchetti, Barbara Campanini, Barbara Pioselli, Kasper Dyrberg Rand

Mol Cell Proteomics· March 2022

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Probing the Impact of Temperature and Substrates on the Conformational Dynamics of the Neurotransmitter:Sodium symporter LeuT.
Dionisie Calugareanu, Ingvar R Möller, Solveig G Schmidt, Claus J Loland, Kasper D Rand

J Mol Biol· January 2022

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Hydrogen/Deuterium Exchange Mass Spectrometry with Integrated Electrochemical Reduction and Microchip-Enabled Deglycosylation for Epitope Mapping of Heavily Glycosylated and Disulfide-Bonded Proteins.
Gerard Comamala, Camilla C Krogh, Vibe S Nielsen, Jörg P Kutter, Josef Voglmeir, Kasper D Rand

Anal Chem· December 2021

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Conformational dynamics of free and membrane-bound human Hsp70 in model cytosolic and endo-lysosomal environments.
Valeria Calvaresi, Line T Truelsen, Sidsel B Larsen, Nikolaj H T Petersen, Thomas Kirkegaard, Kasper D Rand

Commun Biol· December 2021

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Hydrogen-Deuterium Exchange Mass Spectrometry with Integrated Size-Exclusion Chromatography for Analysis of Complex Protein Samples.
Valeria Calvaresi, Andreas Redsted, Nathalie Norais, Kasper D Rand

Anal Chem· August 2021

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Epitope and Paratope Mapping by HDX-MS Combined with SPR Elucidates the Difference in Bactericidal Activity of Two Anti-NadA Monoclonal Antibodies.
Laura R Grauslund, Valeria Calvaresi, Werner Pansegrau, Nathalie Norais, Kasper D Rand

J Am Soc Mass Spectrom· July 2021

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Probing the Conformational Dynamics of Affinity-Enhanced T Cell Receptor Variants upon Binding the Peptide-Bound Major Histocompatibility Complex by Hydrogen/Deuterium Exchange Mass Spectrometry.
Patrick S Merkle, Esben Trabjerg, Song Hongjian, Mathias Ferber, Michel A Cuendet, Kasper D Rand

Biochemistry· March 2021

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Thiol-ene microfluidic chip for fast on-chip sample clean-up, separation and ESI mass spectrometry of peptides and proteins.
Rasmus R Svejdal, Drago Sticker, Claus Sønderby, Jörg P Kutter, Kasper D Rand

Anal Chim Acta· December 2020

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Deglycosylation by the Acidic Glycosidase PNGase H Enables Analysis of N-Linked Glycoproteins by Hydrogen/Deuterium Exchange Mass Spectrometry.
Gerard Comamala, Jeppe B Madsen, Josef Voglmeir, Ya-Min Du, Pernille F Jensen, Kasper D Rand

J Am Soc Mass Spectrom· November 2020

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Probing the conformational impact of detergents on the integral membrane protein LeuT by global HDX-MS.
Ingvar R Möller, Patrick S Merkle, Dionisie Calugareanu, Gerard Comamala, Solveig Gaarde Schmidt, Kasper D Rand

J Proteomics· August 2020

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Discovery of Highly Active Recombinant PNGase H Variants Through the Rational Exploration of Unstudied Acidobacterial Genomes.
Rui-Rui Guo, Gerard Comamala, Huan-Huan Yang, Marius Gramlich, Ya-Min Du, Kasper Dyrberg Rand

Front Bioeng Biotechnol· July 2020

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Hydrogen/deuterium exchange mass spectrometry with improved electrochemical reduction enables comprehensive epitope mapping of a therapeutic antibody to the cysteine-knot containing vascular endothelial growth factor.
Gerard Comamala, Cornelia Wagner, Pablo Sanz de la Torre, Rasmus U Jakobsen, Maximiliane Hilger, Kasper D Rand

Anal Chim Acta· June 2020

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Conformational heterogeneity of Savinase from NMR, HDX-MS and X-ray diffraction analysis.
Shanshan Wu, Tam T T N Nguyen, Olga V Moroz, Johan P Turkenburg, Jens E Nielsen, Kasper D Rand

PeerJ· June 2020

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An intact C-terminal end of albumin is required for its long half-life in humans.
Jeannette Nilsen, Esben Trabjerg, Algirdas Grevys, Claudia Azevedo, Stephen O Brennan, Kasper Dyrberg Rand

Commun Biol· April 2020

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Investigating surrogate cerebrospinal fluid matrix compositions for use in quantitative LC-MS analysis of therapeutic antibodies in the cerebrospinal fluid.
Jens Rose Fogh, Anne-Marie Jacobsen, Tam T T N Nguyen, Kasper D Rand, Line Rørbæk Olsen

Anal Bioanal Chem· March 2020

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Benzisothiazolinone Derivatives as Potent Allosteric Monoacylglycerol Lipase Inhibitors That Functionally Mimic Sulfenylation of Regulatory Cysteines.
Riccardo Castelli, Laura Scalvini, Federica Vacondio, Alessio Lodola, Mattia Anselmi, Kasper D Rand

J Med Chem· February 2020

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Improving the Sequence Coverage of Integral Membrane Proteins during Hydrogen/Deuterium Exchange Mass Spectrometry Experiments.
Ingvar R Möller, Marika Slivacka, Jiří Hausner, Anne Kathrine Nielsen, Eliška Pospíšilová, Kasper D Rand

Anal Chem· September 2019

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