Publications by authors named "Katalin Modis"

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Cystathionine Gamma-Lyase Regulates TNF-α-Mediated Injury Response in Human Colonic Epithelial Cells and Colonoids.
Francisco Arroyo Almenas, Gábor Törő, Peter Szaniszlo, Manjit Maskey, Ketan K Thanki

Antioxidants (Basel)· August 2024

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Hydrogen Sulfide Ameliorates SARS-CoV-2-Associated Lung Endothelial Barrier Disruption.
Olivier Escaffre, Peter Szaniszlo, Gabor Törő, Caitlyn L Vilas, Brenna J Servantes

Biomedicines· June 2023

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Antithrombin Activity Is Associated with Persistent Thromboinflammation and Mortality in Patients with Severe COVID-19 Illness.
Amber Chen-Goodspeed, Goutham Dronavalli, Xu Zhang, Jeanette M Podbielski, Bela Patel, Katalin Modis

Acta Haematol· March 2023

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Deletion of cystathionine-γ-lyase in bone marrow-derived cells promotes colitis-associated carcinogenesis.
Ketan K Thanki, Paul Johnson, Edward J Higgins, Manjit Maskey, Ches'Nique Phillips

Redox Biol· September 2022

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Sequential Accumulation of 'Driver' Pathway Mutations Induces the Upregulation of Hydrogen-Sulfide-Producing Enzymes in Human Colonic Epithelial Cell Organoids.
Kelly Ascenção, Nahzli Dilek, Karim Zuhra, Katalin Módis, Toshiro Sato

Antioxidants (Basel)· September 2022

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Definition of germ layer cell lineage alternative splicing programs reveals a critical role for Quaking in specifying cardiac cell fate.
W Samuel Fagg, Naiyou Liu, Ulrich Braunschweig, Karen Larissa Pereira de Castro, Xiaoting Chen, Katalin Modis

Nucleic Acids Res· May 2022

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Efficacy of Novel Aminooxyacetic Acid Prodrugs in Colon Cancer Models: Towards Clinical Translation of the Cystathionine β-Synthase Inhibition Concept.
Mark R Hellmich, Celia Chao, Katalin Módis, Ye Ding, John R Zatarain

Biomolecules· July 2021

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Arginine vasopressin receptor 2 activation promotes microvascular permeability in sepsis.
Ernesto Lopez, Satoshi Fukuda, Katalin Modis, Osamu Fujiwara, Baigal Enkhtaivan

Pharmacol Res· January 2021

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3-Mercaptopyruvate sulfurtransferase supports endothelial cell angiogenesis and bioenergetics.
Armita Abdollahi Govar, Gábor Törő, Peter Szaniszlo, Athanasia Pavlidou, Sofia-Iris Bibli

Br J Pharmacol· February 2020

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Cystathionine-γ-lyase (CSE) deficiency increases erythropoiesis and promotes mitochondrial electron transport via the upregulation of coproporphyrinogen III oxidase and consequent stimulation of heme biosynthesis.
Katalin Módis, V-M Sadagopa Ramanujam, Armita Abdollahi Govar, Ernesto Lopez, Karl E Anderson

Biochem Pharmacol· November 2019

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Role of endogenous and exogenous nitric oxide, carbon monoxide and hydrogen sulfide in HCT116 colon cancer cell proliferation.
Gabor Oláh, Katalin Módis, Gabor Törö, Mark R Hellmich, Bartosz Szczesny

Biochem Pharmacol· March 2018

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Development of a stretch-induced neurotrauma model for medium-throughput screening in vitro: identification of rifampicin as a neuroprotectant.
Isabel López-García, Domokos Gerő, Bartosz Szczesny, Petra Szoleczky, Gabor Olah

Br J Pharmacol· January 2018

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Upregulation of Cystathionine-β-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis.
Ches'Nique M Phillips, John R Zatarain, Michael E Nicholls, Craig Porter, Steve G Widen

Cancer Res· November 2017

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HS-induced S-sulfhydration of lactate dehydrogenase a (LDHA) stimulates cellular bioenergetics in HCT116 colon cancer cells.
Ashley A Untereiner, Gabor Oláh, Katalin Módis, Mark R Hellmich, Csaba Szabo

Biochem Pharmacol· July 2017

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Screening of a composite library of clinically used drugs and well-characterized pharmacological compounds for cystathionine β-synthase inhibition identifies benserazide as a drug potentially suitable for repurposing for the experimental therapy of colon cancer.
Nadiya Druzhyna, Bartosz Szczesny, Gabor Olah, Katalin Módis, Antonia Asimakopoulou

Pharmacol Res· November 2016

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S-Sulfhydration of ATP synthase by hydrogen sulfide stimulates mitochondrial bioenergetics.
Katalin Módis, YoungJun Ju, Akbar Ahmad, Ashley A Untereiner, Zaid Altaany

Pharmacol Res· November 2016

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Cystathionine-beta-synthase inhibition for colon cancer: Enhancement of the efficacy of aminooxyacetic acid via the prodrug approach.
Celia Chao, John R Zatarain, Ye Ding, Ciro Coletta, Amy A Mrazek

Mol Med· September 2016

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Stimulatory effect of CSE-generated H2S on hepatic mitochondrial biogenesis and the underlying mechanisms.
Ashley A Untereiner, Ming Fu, Katalin Módis, Rui Wang, YoungJun Ju

Nitric Oxide· August 2016

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Regulation of Vascular Tone, Angiogenesis and Cellular Bioenergetics by the 3-Mercaptopyruvate Sulfurtransferase/H2S Pathway: Functional Impairment by Hyperglycemia and Restoration by DL-α-Lipoic Acid.
Ciro Coletta, Katalin Módis, Bartosz Szczesny, Attila Brunyánszki, Gábor Oláh

Mol Med· February 2015

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Effect of S-adenosyl-L-methionine (SAM), an allosteric activator of cystathionine-β-synthase (CBS) on colorectal cancer cell proliferation and bioenergetics in vitro.
Katalin Módis, Ciro Coletta, Antonia Asimakopoulou, Bartosz Szczesny, Celia Chao

Nitric Oxide· September 2014

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AP39, a novel mitochondria-targeted hydrogen sulfide donor, stimulates cellular bioenergetics, exerts cytoprotective effects and protects against the loss of mitochondrial DNA integrity in oxidatively stressed endothelial cells in vitro.
Bartosz Szczesny, Katalin Módis, Kazunori Yanagi, Ciro Coletta, Sophie Le Trionnaire

Nitric Oxide· September 2014

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Endothelial dysfunction is a potential contributor to multiple organ failure and mortality in aged mice subjected to septic shock: preclinical studies in a murine model of cecal ligation and puncture.
Ciro Coletta, Katalin Módis, Gábor Oláh, Attila Brunyánszki, Daniela S Herzig

Crit Care· September 2014

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Regulation of mitochondrial bioenergetic function by hydrogen sulfide. Part II. Pathophysiological and therapeutic aspects.
Katalin Módis, Eelke M Bos, Enrico Calzia, Harry van Goor, Ciro Coletta

Br J Pharmacol· April 2014

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Regulation of mitochondrial bioenergetic function by hydrogen sulfide. Part I. Biochemical and physiological mechanisms.
Csaba Szabo, Céline Ransy, Katalin Módis, Mireille Andriamihaja, Baptiste Murghes

Br J Pharmacol· April 2014

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Hydrogen sulfide-mediated stimulation of mitochondrial electron transport involves inhibition of the mitochondrial phosphodiesterase 2A, elevation of cAMP and activation of protein kinase A.
Katalin Módis, Panagiotis Panopoulos, Ciro Coletta, Andreas Papapetropoulos, Csaba Szabo

Biochem Pharmacol· November 2013

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