Publications by authors named "Katherine Chaney"

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Pharmacogenomic synthetic lethal screens reveal hidden vulnerabilities and new therapeutic approaches for treatment of NF1-associated tumors.
Kyle B Williams, Alex T Larsson, Bryant J Keller, Katherine E Chaney, Rory L Williams

Mol Cancer Ther· October 2025

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Pharmacogenomic synthetic lethal screens reveal hidden vulnerabilities and new therapeutic approaches for treatment of NF1-associated tumors.
Kyle B Williams, Alex T Larsson, Bryant J Keller, Katherine E Chaney, Rory L Williams

bioRxiv· November 2024

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Cryopreserved leukapheresis material can be transferred from controlled rate freezers to ultracold storage at warmer temperatures without affecting downstream CAR-T cell culture performance and in-vitro functionality.
Jiaming Wei, Katherine Chaney, Woo Jin Shim, Heyu Chen, Grace Leonard

Cryobiology· June 2024

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Long-term outcomes and predictors of early response, late relapse, and survival for patients treated with bispecific LV20.19 CAR T-cells.
Joanna C Zurko, Timothy S Fenske, Bryon D Johnson, Daniel Bucklan, Aniko Szabo, Katherine Chaney

Am J Hematol· December 2022

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Bispecific targeting of CD20 and CD19 increases polyfunctionality of chimeric antigen receptor T-cell products in B-cell malignancies.
Joanna C Zurko, Huiqing Xu, Katherine Chaney, Dina Schneider, Aniko Szabo

Cytotherapy· August 2022

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P2RY14 cAMP signaling regulates Schwann cell precursor self-renewal, proliferation, and nerve tumor initiation in a mouse model of neurofibromatosis.
Jennifer Patritti Cram, Jianqiang Wu, Robert A Coover, Tilat A Rizvi, Katherine E Chaney

Elife· March 2022

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PD-1 blockade after bispecific LV20.19 CAR T modulates CAR T-cell immunophenotype without meaningful clinical response.
Joanna Zurko, Katherine Chaney, John M Astle, Bryon D Johnson, Parameswaran Hari

Haematologica· October 2021

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WNT5A inhibition alters the malignant peripheral nerve sheath tumor microenvironment and enhances tumor growth.
Craig S Thomson, Jay Pundavela, Melissa R Perrino, Robert A Coover, Kwangmin Choi, Katherine E Chaney

Oncogene· June 2021

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A molecular basis for neurofibroma-associated skeletal manifestations in NF1.
Yun Ma, Andrea M Gross, Eva Dombi, Alexander Pemov, Kwangmin Choi, Katherine Chaney

Genet Med· November 2020

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Loss in a Model of Neurofibroma Demonstrates Stepwise Tumor Progression to Atypical Neurofibroma and MPNST.
Katherine E Chaney, Melissa R Perrino, Leah J Kershner, Ami V Patel, Jianqiang Wu

Cancer Res· November 2020

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Polo-like kinase 1 as a therapeutic target for malignant peripheral nerve sheath tumors (MPNST) and schwannomas.
Jianman Guo, Katherine E Chaney, Kwangmin Choi, Gabriela Witek, Ami V Patel

Am J Cancer Res· March 2020

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Targeted Inhibition of the Dual Specificity Phosphatases DUSP1 and DUSP6 Suppress MPNST Growth via JNK.
Annmarie Ramkissoon, Katherine E Chaney, David Milewski, Kyle B Williams, Rory L Williams

Clin Cancer Res· July 2019

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Tonic ATP-mediated growth suppression in peripheral nerve glia requires arrestin-PP2 and is evaded in NF1.
Robert A Coover, Tabitha E Healy, Li Guo, Katherine E Chaney, Robert F Hennigan

Acta Neuropathol Commun· November 2018

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Aurora A kinase inhibition enhances oncolytic herpes virotherapy through cytotoxic synergy and innate cellular immune modulation.
Mark A Currier, Les Sprague, Tilat A Rizvi, Brooke Nartker, Chun-Yu Chen, Katherine E Chaney

Oncotarget· March 2017

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CK2 blockade causes MPNST cell apoptosis and promotes degradation of β-catenin.
Jed J Kendall, Katherine E Chaney, Ami V Patel, Tilat A Rizvi, David A Largaespada

Oncotarget· August 2016

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An ShRNA Screen Identifies MEIS1 as a Driver of Malignant Peripheral Nerve Sheath Tumors.
Ami V Patel, Katherine E Chaney, Kwangmin Choi, David A Largaespada, Ashish R Kumar

EBioMedicine· July 2016

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