Publications by authors named "Kathryn Appleton"

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Inhibition of the Myocardin-Related Transcription Factor Pathway Increases Efficacy of Trametinib in -Mutant Melanoma Cell Lines.
Kathryn M Appleton, Charuta C Palsuledesai, Sean A Misek, Maja Blake, Joseph Zagorski

Cancers (Basel)· April 2021

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PD-1/PD-L1 checkpoint inhibitors in combination with olaparib display antitumor activity in ovarian cancer patient-derived three-dimensional spheroid cultures.
Kathryn M Appleton, Ashley K Elrod, Katy A Lassahn, Stephen Shuford, Lillia M Holmes

Cancer Immunol Immunother· March 2021

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S1P in HDL promotes interaction between SR-BI and S1PR1 and activates S1PR1-mediated biological functions: calcium flux and S1PR1 internalization.
Mi-Hye Lee, Kathryn M Appleton, Hesham M El-Shewy, Mary G Sorci-Thomas, Michael J Thomas

J Lipid Res· February 2017

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Pharmacological Inhibition of Myocardin-related Transcription Factor Pathway Blocks Lung Metastases of RhoC-Overexpressing Melanoma.
Andrew J Haak, Kathryn M Appleton, Erika M Lisabeth, Sean A Misek, Yajing Ji

Mol Cancer Ther· January 2017

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The conformational signature of β-arrestin2 predicts its trafficking and signalling functions.
Mi-Hye Lee, Kathryn M Appleton, Erik G Strungs, Joshua Y Kwon, Thomas A Morinelli

Nature· March 2016

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Development of inhibitors of heterotrimeric Gαi subunits.
Kathryn M Appleton, Kevin J Bigham, Christopher C Lindsey, Starr Hazard, Jonel Lirjoni

Bioorg Med Chem· July 2014

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Suppression of GNAI2 message in ovarian cancer.
John R Raymond, Kathryn M Appleton, Jennifer Y Pierce, Yuri K Peterson

J Ovarian Res· January 2014

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Biasing the parathyroid hormone receptor: relating in vitro ligand efficacy to in vivo biological activity.
Kathryn M Appleton, Mi-Hye Lee, Christian Alele, Christine Alele, Deirdre K Luttrell

Methods Enzymol· July 2013

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Emergent biological properties of arrestin pathway-selective biased agonism.
Kathryn M Appleton, Louis M Luttrell

J Recept Signal Transduct Res· June 2013

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The arrestin-selective angiotensin AT1 receptor agonist [Sar1,Ile4,Ile8]-AngII negatively regulates bradykinin B2 receptor signaling via AT1-B2 receptor heterodimers.
Parker C Wilson, Mi-Hye Lee, Kathryn M Appleton, Hesham M El-Shewy, Thomas A Morinelli

J Biol Chem· June 2013

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A high-content, live-cell, and real-time approach to the quantitation of ligand-induced β-Arrestin2 and Class A/Class B GPCR mobilization.
Anthony P Leonard, Kathryn M Appleton, Louis M Luttrell, Yuri K Peterson

Microsc Microanal· February 2013

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Differential induction of CYP1A1 and CYP1B1 by benzo[a]pyrene in oral squamous cell carcinoma cell lines and by tobacco smoking in oral mucosa.
Angela C Chi, Kathryn Appleton, Joel B Henriod, Joe W Krayer, Nicole M Marlow

Oral Oncol· November 2009

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