Publications by authors named "Kathryn Simpson"

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Small-cell lung cancer: anatomy of an immune-cold tumor.
David Millrine, Kathryn L Simpson, Fiona Blackhall, Caroline Dive

Trends Cancer· December 2025

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Maternal physiological parameters and routine laboratory tests to screen for maternal sepsis: an observational cohort study.
T Culling, C Bertorelli, A Strang, S Oram, F Faggian, Kathryn Simpson

Int J Obstet Anesth· August 2025

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Circulating Tumor Cells Shed Shearosome Extracellular Vesicles in Capillary Bifurcations That Activate Endothelial and Immune Cells.
Angelos Vrynas, Salime Bazban-Shotorbani, Sara Arfan, Karishma Satia, Brian Cunningham, Kathryn L Simpson

Adv Sci (Weinh)· August 2025

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Challenges of small cell lung cancer heterogeneity and phenotypic plasticity.
Kathryn L Simpson, Dominic G Rothwell, Fiona Blackhall, Caroline Dive

Nat Rev Cancer· June 2025

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Functional characterization of the ATOH1 molecular subtype indicates a pro-metastatic role in small cell lung cancer.
Alessia Catozzi, Maria Peiris Pagès, Sam Humphrey, Mitchell Revill, Derrick Morgan, Kathryn L Simpson

Cell Rep· May 2025

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Circulating tumor cells shed shearosome extracellular vesicles in capillary bifurcations that activate endothelial and immune cells.
Angelos Vrynas, Salime Bazban-Shotorbani, Sara Arfan, Karishma Satia, Brian Cunningham, Kathryn L Simpson

bioRxiv· April 2025

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Cell-free and extrachromosomal DNA profiling of small cell lung cancer.
Roya Behrouzi, Alexandra Clipson, Kathryn L Simpson, Fiona Blackhall, Dominic G Rothwell

Trends Mol Med· January 2025

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Functional Characterisation of the ATOH1 Molecular Subtype Indicates a Pro-Metastatic Role in Small Cell Lung Cancer.
Alessia Catozzi, Maria Peiris-Pagès, Sam Humphrey, Mitchell Revill, Derrick Morgan, Kathryn L Simpson

bioRxiv· February 2024

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Lineage Plasticity in SCLC Generates Non-Neuroendocrine Cells Primed for Vasculogenic Mimicry.
Sarah M Pearsall, Stuart C Williamson, Sam Humphrey, Ellyn Hughes, Derrick Morgan, Kathryn L Simpson

J Thorac Oncol· October 2023

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Crosstalk between small-cell lung cancer cells and astrocytes mimics brain development to promote brain metastasis.
Fangfei Qu, Siqi C Brough, Wojciech Michno, Chioma J Madubata, Griffin G Hartmann, Kathryn L Simpson

Nat Cell Biol· October 2023

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FOXC2 promotes vasculogenic mimicry and resistance to anti-angiogenic therapy.
Ian G Cannell, Kirsty Sawicka, Isabella Pearsall, Sophia A Wild, Lauren Deighton, Kathryn L Simpson

Cell Rep· August 2023

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Reduction in transfer of micro-organisms between patients and staff using short-sleeved gowns and hand/arm hygiene in intensive care during the COVID-19 pandemic: A simulation-based randomised trial.
Laura Vincent, Mudathir Ibrahim, Joanne Kitchin, Claire Pickering, Jennie Wilson, Kathryn Simpson

J Intensive Care Soc· August 2023

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cfDNA methylome profiling for detection and subtyping of small cell lung cancers.
Francesca Chemi, Simon P Pearce, Alexandra Clipson, Steven M Hill, Alicia-Marie Conway, Kathryn L Simpson

Nat Cancer· October 2022

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mSep: investigating physiological and immune-metabolic biomarkers in septic and healthy pregnant women to predict feto-maternal immune health - a prospective observational cohort study protocol.
Simran Sharma, Summia Zaher, Patrícia R S Rodrigues, Luke C Davies, Sarah Edkins, Kathryn Simpson

BMJ Open· September 2022

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Expanding Therapeutic Opportunities for Extrapulmonary Neuroendocrine Carcinoma.
Melissa Frizziero, Elaine Kilgour, Kathryn L Simpson, Dominic G Rothwell, David A Moore

Clin Cancer Res· May 2022

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A conserved YAP/Notch/REST network controls the neuroendocrine cell fate in the lungs.
Yan Ting Shue, Alexandros P Drainas, Nancy Yanzhe Li, Sarah M Pearsall, Derrick Morgan, Kathryn L Simpson

Nat Commun· May 2022

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TIAM1-RAC1 promote small-cell lung cancer cell survival through antagonizing Nur77-induced BCL2 conformational change.
Aishwarya Payapilly, Ryan Guilbert, Tine Descamps, Gavin White, Peter Magee, Kathryn L Simpson

Cell Rep· November 2021

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Clinical Case Reports on the acceptability and tolerance of a High-Energy whey peptide-based Pediatric oral nutritional supplement in children aged over 12 months.
Kathryn Simpson

Clin Case Rep· October 2021

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New York State Local Health Department Preparedness for and Response to the COVID-19 Pandemic: An In-Progress Review.
Sarah Ravenhall, Nicole A Levy, Kathryn Simpson, Molly Fleming, Mayela Arana

J Public Health Manag Pract· April 2021

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Small cell lung cancer enters the era of precision medicine.
Kristopher K Frese, Kathryn L Simpson, Caroline Dive

Cancer Cell· March 2021

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The Rare YAP1 Subtype of SCLC Revisited in a Biobank of 39 Circulating Tumor Cell Patient Derived Explant Models: A Brief Report.
Sarah M Pearsall, Sam Humphrey, Mitchell Revill, Derrick Morgan, Kristopher K Frese, Kathryn L Simpson

J Thorac Oncol· December 2020

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A biobank of small cell lung cancer CDX models elucidates inter- and intratumoral phenotypic heterogeneity.
Kathryn L Simpson, Ruth Stoney, Kristopher K Frese, Nicole Simms, William Rowe

Nat Cancer· April 2020

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Dynamics of circulating vascular endothelial growth factor-A predict benefit from antiangiogenic cediranib in metastatic or recurrent cervical cancer patients.
Cong Zhou, Sarah Taylor, Jonathan Tugwood, Kathryn Simpson, Gordon C Jayson

Br J Clin Pharmacol· August 2019

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Evaluation of apoptosis imaging biomarkers in a genetic model of cell death.
Vessela Vassileva, Stephen M Stribbling, Chris Barnes, Laurence Carroll, Marta Braga, Kathryn L Simpson

EJNMMI Res· February 2019

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Plasma Tie2 is a tumor vascular response biomarker for VEGF inhibitors in metastatic colorectal cancer.
Gordon C Jayson, Cong Zhou, Alison Backen, Laura Horsley, Kalena Marti-Marti, Kathryn Simpson

Nat Commun· November 2018

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