Publications by authors named "Katrine D Galsgaard"

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Glucagon Receptor Signaling and Lipid Metabolism.
Katrine D Galsgaard, Jens Pedersen, Filip K Knop, Jens J Holst, Nicolai J Wewer Albrechtsen

Front Physiol· April 2019

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In Vivo Inhibition of Dipeptidyl Peptidase 4 and Neprilysin Activity Enables Measurement of GLP-1 Secretion in Male Rats.
Katrine D Galsgaard, Valentina Abba, Rune E Kuhre, Jens J Holst, Bolette Hartmann

J Endocr Soc· December 2025

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GLP-2 and GIP acutely increase superior mesenteric artery blood flow in male rats, and the effect is independent of nitric oxide and vasoactive intestinal peptide.
Katrine D Galsgaard, Bolette Hartmann, Mette M Rosenkilde, Jens J Holst, Lærke S Gasbjerg

Physiol Rep· December 2025

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Single incretin receptor knockout mice do not compensate by increasing glucose-stimulated secretion of the remaining incretin hormone.
Katrine D Galsgaard, Jon Vergara, Sara L Jepsen, Alice Bazzichi, Hannelouise Kissow

Am J Physiol Endocrinol Metab· March 2025

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Female glucagon receptor knockout mice are prone to steatosis but resistant to weight gain when fed a MASH-promoting GAN diet and a high-fat diet.
Katrine D Galsgaard, Emilie Elmelund, Jenna E Hunt, Mark M Smits, Trisha J Grevengoed

Physiol Rep· February 2025

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Understanding the release mechanisms and secretion patterns for glucagon-like peptide-1 using the isolated perfused intestine as a model.
Katrine D Galsgaard, Ida M Modvig, Jens J Holst

Biochem Soc Trans· January 2025

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SGLT2 inhibition alters substrate utilization and mitochondrial redox in healthy and failing rat hearts.
Leigh Goedeke, Yina Ma, Rafael C Gaspar, Ali Nasiri, Jieun Lee, Katrine Douglas Galsgaard

J Clin Invest· December 2024

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Glucagon receptor activation contributes to the development of kidney injury.
Anna Billeschou Bomholt, Christian Dall Johansen, Katrine Douglas Galsgaard, Emilie Elmelund, Marie Winther-Sørensen

Am J Physiol Renal Physiol· November 2024

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In-depth phosphoproteomic profiling of the insulin signaling response in heart tissue and cardiomyocytes unveils canonical and specialized regulation.
Jonathan Samuel Achter, Estefania Torres Vega, Andrea Sorrentino, Konstantin Kahnert, Katrine Douglas Galsgaard

Cardiovasc Diabetol· July 2024

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L-valine is a powerful stimulator of GLP-1 secretion in rodents and stimulates secretion through ATP-sensitive potassium channels and voltage-gated calcium channels.
Ida Marie Modvig, Mark M Smits, Katrine Douglas Galsgaard, Anna Pii Hjørne, Anna Katarzyna Drzazga

Nutr Diabetes· June 2024

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In Vivo Inhibition of Dipeptidyl Peptidase 4 Allows Measurement of GLP-1 Secretion in Mice.
Mark M Smits, Katrine D Galsgaard, Sara Lind Jepsen, Nicolai Wewer Albrechtsen, Bolette Hartmann

Diabetes· May 2024

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Q-Flux: A method to assess hepatic mitochondrial succinate dehydrogenase, methylmalonyl-CoA mutase, and glutaminase fluxes in vivo.
Brandon T Hubbard, Traci E LaMoia, Leigh Goedeke, Rafael C Gaspar, Katrine D Galsgaard

Cell Metab· January 2023

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Glucagon receptor antagonism impairs and glucagon receptor agonism enhances triglycerides metabolism in mice.
Katrine D Galsgaard, Emilie Elmelund, Christian D Johansen, Anna B Bomholt, Hüsün S Kizilkaya

Mol Metab· December 2022

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Opposing effects of chronic glucagon receptor agonism and antagonism on amino acids, hepatic gene expression, and alpha cells.
Emilie Elmelund, Katrine D Galsgaard, Christian D Johansen, Samuel A J Trammell, Anna B Bomholt

iScience· November 2022

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Evaluation of commercially available glucagon receptor antibodies and glucagon receptor expression.
Anna Billeschou Bomholt, Christian Dall Johansen, Jens Bager Christensen, Sasha Alexandra Sampson Kjeldsen, Katrine Douglas Galsgaard

Commun Biol· November 2022

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The Liver-α-Cell Axis in Health and in Disease.
Michael M Richter, Katrine D Galsgaard, Emilie Elmelund, Filip K Knop, Malte P Suppli

Diabetes· September 2022

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Neprilysin Inhibition Increases Glucagon Levels in Humans and Mice With Potential Effects on Amino Acid Metabolism.
Sasha A S Kjeldsen, Lasse H Hansen, Nathalie Esser, Steve Mongovin, Marie Winther-Sørensen, Katrine D Galsgaard

J Endocr Soc· September 2021

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Antagonizing somatostatin receptor subtype 2 and 5 reduces blood glucose in a gut- and GLP-1R-dependent manner.
Sara L Jepsen, Nicolai J Wewer Albrechtsen, Johanne A Windeløv, Katrine D Galsgaard, Jenna E Hunt

JCI Insight· February 2021

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Glucagon acutely regulates hepatic amino acid catabolism and the effect may be disturbed by steatosis.
Marie Winther-Sørensen, Katrine D Galsgaard, Alberto Santos, Samuel A J Trammell, Karolina Sulek

Mol Metab· December 2020

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The Vicious Circle of Hepatic Glucagon Resistance in Non-Alcoholic Fatty Liver Disease.
Katrine D Galsgaard

J Clin Med· December 2020

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Alanine, arginine, cysteine, and proline, but not glutamine, are substrates for, and acute mediators of, the liver-α-cell axis in female mice.
Katrine D Galsgaard, Sara L Jepsen, Sasha A S Kjeldsen, Jens Pedersen, Nicolai J Wewer Albrechtsen

Am J Physiol Endocrinol Metab· June 2020

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Glucagon receptor signaling is not required for -carbamoyl glutamate- and l-citrulline-induced ureagenesis in mice.
Katrine D Galsgaard, Jens Pedersen, Sasha A S Kjeldsen, Marie Winther-Sørensen, Elena Stojanovska

Am J Physiol Gastrointest Liver Physiol· May 2020

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The Liver-α-Cell Axis and Type 2 Diabetes.
Nicolai J Wewer Albrechtsen, Jens Pedersen, Katrine D Galsgaard, Marie Winther-Sørensen, Malte P Suppli

Endocr Rev· October 2019

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Glucagon Receptor Signaling and Glucagon Resistance.
Lina Janah, Sasha Kjeldsen, Katrine D Galsgaard, Marie Winther-Sørensen, Elena Stojanovska

Int J Mol Sci· July 2019

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Glucose and amino acid metabolism in mice depend mutually on glucagon and insulin receptor signaling.
Katrine D Galsgaard, Marie Winther-Sørensen, Jens Pedersen, Sasha A S Kjeldsen, Mette M Rosenkilde

Am J Physiol Endocrinol Metab· April 2019

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