Front Physiol April 2019 PMID 31068828

Glucagon Receptor Signaling and Lipid Metabolism.

Katrine D Galsgaard, Jens Pedersen, Filip K Knop, Jens J Holst, Nicolai J Wewer Albrechtsen

Mentions

24
Peak: 10 in May 2019
across 4 sources since May 2019

Extended reach

119,594
potential audience

Total likes

569

Video views

14,894

Mentions per month

May 2019 – Dec 2025

Where it's discussed

  • X / Twitter13 posts
  • Instagram6 posts
  • News3 articles
  • YouTube2 videos

AI synopsis

What people are saying

The social discussions reflect a strong interest in the article's exploration of glucagon's role beyond glucose metabolism, with posts mentioning effects on liver fat, lipolysis, and relevant pathways like beta-oxidation, demonstrating thoughtful engagement and a view of potential impact on disease treatment strategies.

AgreementModerate agreement

Most discussions acknowledge the significance of glucagon in lipid metabolism, with some supporting its potential regulatory effects, indicating general agreement with the publication's focus.

InterestHigh interest

The posts show high interest, especially with questions about glucagon's broader roles, and references to specific effects on hepatic and adipocyte lipid processes.

EngagementModerate engagement

The comments include references to the research content, such as effects on hepatic beta-oxidation and lipogenesis, suggesting moderate levels of detailed engagement.

ImpactModerate impact

The discussions indicate recognition of the research's potential impact on understanding diabetes and lipid regulation, though mostly from a conceptual perspective rather than direct application.

Abstract in brief

  • Glucagon, a hormone secreted during hypoglycemia, plays a crucial role in stimulating liver glucose production and impacts lipid metabolism, with dysregulated secretion linked to type 2 diabetes and hyperglycemia.
  • While blocking glucagon receptors has been explored as a treatment for type 2 diabetes, concerns arise about increased liver fat and LDL cholesterol, but in animal studies, enhanced glucagon signaling can improve lipid breakdown and reduce liver fat.
  • The overall effect of glucagon on whole-body fat breakdown, especially in human fat tissue, remains debated, but combined therapies targeting glucagon pathways show promise in improving lipid profiles and reducing liver fat.]

Top posts

Most liked on X and Bluesky
Daniel J Drucker
@DanielJDrucker · X

Glucagon Receptor Signaling and Lipid Metabolism https://t.co/oTGvpbmHTX

May 10, 2019 · 13 likes · 4 shares · 34,948 followers View post →
Mercodia
@Mercodia · X

We know glucagon has a role in glucose metabolism, but what about its importance in lipid metabolism? This review from @nicwin98 discusses this, via effects on hepatic beta-oxidation and lipogenesis, and increased lipolysis in adipocytes. ➡️ https://t.co/C2FOelTFky https://t.co/35eROjzMo6

May 10, 2019 · 7 likes · 4 shares · 390 followers View post →
Daniel J Drucker
@DanielJDrucker · X

And https://t.co/oTGvpbmHTX

Jul 11, 2019 · 6 likes · 1 share · 34,948 followers View post →
Duque de Caixas
@AlfredoDeCaixas · X

RT @DanielJDrucker: Glucagon Receptor Signaling and Lipid Metabolism https://t.co/oTGvpbmHTX

May 10, 2019 · 4 shares · 27,476 followers View post →
eleanorina
@_eleanorina · X

RT @DanielJDrucker: And https://t.co/oTGvpbmHTX

Jul 11, 2019 · 1 share · 3,175 followers View post →
Dr. Danielle Dean
@deanlab8 · X

Glucagon and lipid metabolism https://t.co/q582VS6sAW

May 10, 2019 · 821 followers View post →

All mentions

zaid
@zaidlopezz · X

RT @DanielJDrucker: And https://t.co/oTGvpbmHTX

Jul 11, 2019 · 1 share · 278 followers View post →
eleanorina
@_eleanorina · X

RT @DanielJDrucker: And https://t.co/oTGvpbmHTX

Jul 11, 2019 · 1 share · 3,175 followers View post →
Daniel J Drucker
@DanielJDrucker · X

And https://t.co/oTGvpbmHTX

Jul 11, 2019 · 6 likes · 1 share · 34,948 followers View post →
zaid
@zaidlopezz · X

RT @DanielJDrucker: Glucagon Receptor Signaling and Lipid Metabolism https://t.co/oTGvpbmHTX

May 11, 2019 · 4 shares · 278 followers View post →
Stewart Jeromson
@StewartJeromson · X

RT @Mercodia: We know glucagon has a role in glucose metabolism, but what about its importance in lipid metabolism? This review from @nicw…

May 10, 2019 · 4 shares · 403 followers View post →
Ana Miguel Cruz, PhD
@AnaMiguelCruz · X

RT @Mercodia: We know glucagon has a role in glucose metabolism, but what about its importance in lipid metabolism? This review from @nicw…

May 10, 2019 · 4 shares · 616 followers View post →
Ana Miguel Cruz, PhD
@AnaMiguelCruz · X

RT @DanielJDrucker: Glucagon Receptor Signaling and Lipid Metabolism https://t.co/oTGvpbmHTX

May 10, 2019 · 4 shares · 616 followers View post →
Duque de Caixas
@AlfredoDeCaixas · X

RT @DanielJDrucker: Glucagon Receptor Signaling and Lipid Metabolism https://t.co/oTGvpbmHTX

May 10, 2019 · 4 shares · 27,476 followers View post →
BIOCOM Africa
@biocomafricarsa · X

RT @Mercodia: We know glucagon has a role in glucose metabolism, but what about its importance in lipid metabolism? This review from @nicw…

May 10, 2019 · 4 shares · 118 followers View post →
Dr. Danielle Dean
@deanlab8 · X

Glucagon and lipid metabolism https://t.co/q582VS6sAW

May 10, 2019 · 821 followers View post →
Nicolai J. Wewer Albrechtsen
@nicwin98 · X

RT @Mercodia: We know glucagon has a role in glucose metabolism, but what about its importance in lipid metabolism? This review from @nicw…

May 10, 2019 · 4 shares · 467 followers View post →
Mercodia
@Mercodia · X

We know glucagon has a role in glucose metabolism, but what about its importance in lipid metabolism? This review from @nicwin98 discusses this, via effects on hepatic beta-oxidation and lipogenesis, and increased lipolysis in adipocytes. ➡️ https://t.co/C2FOelTFky https://t.co/35eROjzMo6

May 10, 2019 · 7 likes · 4 shares · 390 followers View post →
Daniel J Drucker
@DanielJDrucker · X

Glucagon Receptor Signaling and Lipid Metabolism https://t.co/oTGvpbmHTX

May 10, 2019 · 13 likes · 4 shares · 34,948 followers View post →
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