Publications by authors named "Katya Marjon"

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Reciprocal links between methionine metabolism, DNA repair and therapy resistance in glioblastoma.
Navyateja Korimerla, Baharan Meghdadi, Isra Haq, Kari Wilder-Romans, Jie Xu, Katya Marjon

bioRxiv· November 2024

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Leveraging Structure-Based Drug Design to Identify Next-Generation MAT2A Inhibitors, Including Brain-Penetrant and Peripherally Efficacious Leads.
Mingzong Li, Zenon Konteatis, Nelamangala Nagaraja, Yue Chen, Shubao Zhou, Katya Marjon

J Med Chem· March 2022

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Discovery of AG-270, a First-in-Class Oral MAT2A Inhibitor for the Treatment of Tumors with Homozygous Deletion.
Zenon Konteatis, Jeremy Travins, Stefan Gross, Katya Marjon, Amelia Barnett

J Med Chem· April 2021

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MAT2A Inhibition Blocks the Growth of MTAP-Deleted Cancer Cells by Reducing PRMT5-Dependent mRNA Splicing and Inducing DNA Damage.
Peter Kalev, Marc L Hyer, Stefan Gross, Zenon Konteatis, Chi-Chao Chen, Katya Marjon

Cancer Cell· February 2021

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Corrigendum: mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer.
Amaia Zabala-Letona, Amaia Arruabarrena-Aristorena, Natalia Martín-Martín, Sonia Fernandez-Ruiz, James D Sutherland, Katya Marjon

Nature· February 2018

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mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer.
Amaia Zabala-Letona, Amaia Arruabarrena-Aristorena, Natalia Martín-Martín, Sonia Fernandez-Ruiz, James D Sutherland, Katya Marjon

Nature· July 2017

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MTAP Deletions in Cancer Create Vulnerability to Targeting of the MAT2A/PRMT5/RIOK1 Axis.
Katya Marjon, Michael J Cameron, Phong Quang, Michelle F Clasquin, Everton Mandley

Cell Rep· April 2016

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