Publications by authors named "Kavankumar Patel"

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Identification of B. anthracis N(5)-carboxyaminoimidazole ribonucleotide mutase (PurE) active site binding compounds via fragment library screening.
Hao Lei, Christopher Jones, Tian Zhu, Kavankumar Patel, Nina M Wolf

Bioorg Med Chem· February 2016

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Inhibitor recognition specificity of MERS-CoV papain-like protease may differ from that of SARS-CoV.
Hyun Lee, Hao Lei, Bernard D Santarsiero, Joseph L Gatuz, Shuyi Cao, Kavankumar Patel

ACS Chem Biol· June 2015

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High-throughput screening (HTS) and hit validation to identify small molecule inhibitors with activity against NS3/4A proteases from multiple hepatitis C virus genotypes.
Hyun Lee, Tian Zhu, Kavankumar Patel, Yan-Yan Zhang, Lena Truong

PLoS One· June 2014

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Identification of novel drug scaffolds for inhibition of SARS-CoV 3-Chymotrypsin-like protease using virtual and high-throughput screenings.
Hyun Lee, Anuradha Mittal, Kavankumar Patel, Joseph L Gatuz, Lena Truong

Bioorg Med Chem· January 2014

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Synergistic inhibitor binding to the papain-like protease of human SARS coronavirus: mechanistic and inhibitor design implications.
Hyun Lee, Shuyi Cao, Kirk E Hevener, Lena Truong, Joseph L Gatuz, Kavankumar Patel

ChemMedChem· August 2013

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High-level expression, purification, and characterization of Staphylococcus aureus dihydroorotase (PyrC) as a cleavable His-SUMO fusion.
Lena Truong, Kirk E Hevener, Amy J Rice, Kavankumar Patel, Michael E Johnson

Protein Expr Purif· March 2013

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Fragment-based drug discovery using a multidomain, parallel MD-MM/PBSA screening protocol.
Tian Zhu, Hyun Lee, Hao Lei, Christopher Jones, Kavankumar Patel

J Chem Inf Model· March 2013

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Identification of non-macrocyclic small molecule inhibitors against the NS3/4A serine protease of hepatitis C virus through in silico screening.
Rima Chaudhuri, Hyun Lee, Lena Truong, Jaime Torres, Kavankumar Patel

J Chem Inf Model· August 2012

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