Publications by authors named "Kay M Brummond"

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A Predictive Model for Thiol Reactivity of -Heteroaryl α-Methylene-γ-Lactams─A Medicinally Relevant Covalent Reactive Group.
Mariah C Meehan, Grace E Scofield, Corrinne E Stahl, Jacob A Wolfe, W Seth Horne, Kay M Brummond

J Med Chem· June 2025

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Stereo-Differentiating Asymmetric Rh(I)-Catalyzed Pauson-Khand Reaction: A DFT-Informed Approach to Thapsigargin Stereoisomers.
Fatemeh Haghighi, Luke T Jesikiewicz, Corrinne E Stahl, Jordan Nafie, Amanda Ortega-Vega, Kay M Brummond

J Am Chem Soc· January 2025

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Systematic Parameter Determination Aimed at a Catalyst-Controlled Asymmetric Rh(I)-Catalyzed Pauson-Khand Reaction.
Yifan Qi, Luke T Jesikiewicz, Grace E Scofield, Peng Liu, Kay M Brummond

ACS Catal· November 2024

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A Celebration of the Publication of the 100th Volume of .
Margaret M Faul, Kay M Brummond

J Org Chem· December 2023

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A Celebration of the Publication of the 100th Volume of .
Margaret M Faul, Kay M Brummond

J Med Chem· December 2023

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A Celebration of the Publication of the 100th Volume of .
Margaret M Faul, Kay M Brummond

Org Lett· December 2023

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A Celebration of the Publication of the 100th Volume of .
Margaret M Faul, Kay M Brummond

ACS Org Inorg Au· December 2023

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A Celebration of the Publication of the 100th Volume of .
Margaret M Faul, Kay M Brummond

ACS Med Chem Lett· December 2023

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A Celebration of the Publication of the 100th Volume of .
Margaret M Faul, Kay M Brummond

J Am Chem Soc· November 2023

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Thiol Reactivity of -Aryl α-Methylene-γ-lactams: Influence of the Guaianolide Structure.
Daniel P Dempe, Chong-Lei Ji, Peng Liu, Kay M Brummond

J Org Chem· August 2022

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Rh(I)-Catalyzed Allenic Pauson-Khand Reaction to Access the Thapsigargin Core: Influence of Furan and Allenyl Chloroacetate Groups on Enantioselectivity.
Eric D Deihl, Luke T Jesikiewicz, Logan J Newman, Peng Liu, Kay M Brummond

Org Lett· February 2022

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Thiol Reactivity of -Aryl α-Methylene-γ-lactams: A Reactive Group for Targeted Covalent Inhibitor Design.
Tuğçe G Erbay, Daniel P Dempe, Bhaskar Godugu, Peng Liu, Kay M Brummond

J Org Chem· September 2021

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Synthesis of Guaianolide Analogues with a Tunable α-Methylene-γ-lactam Electrophile and Correlating Bioactivity with Thiol Reactivity.
Paul A Jackson, Henry A M Schares, Katherine F M Jones, John C Widen, Daniel P Dempe, Kay M Brummond

J Med Chem· December 2020

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Metal-Free C-C Coupling of an Allenyl Sulfone with Picolyl Amides to Access Vinyl Sulfones via Pyridine-Initiated In Situ Generation of Sulfinate Anion.
Humair M Omer, Peng Liu, Kay M Brummond

J Org Chem· June 2020

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Computationally Guided Catalyst Design in the Type I Dynamic Kinetic Asymmetric Pauson-Khand Reaction of Allenyl Acetates.
Lauren C Burrows, Luke T Jesikiewicz, Gang Lu, Steven J Geib, Peng Liu, Kay M Brummond

J Am Chem Soc· October 2017

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Intramolecular Didehydro-Diels-Alder Reaction for the Synthesis of Benzo- and Dihydrobenzo-Fused Heterocycles.
Ashley E Bober, Justin T Proto, Kay M Brummond

Org Lett· April 2017

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Covalent Modifiers: A Chemical Perspective on the Reactivity of α,β-Unsaturated Carbonyls with Thiols via Hetero-Michael Addition Reactions.
Paul A Jackson, John C Widen, Daniel A Harki, Kay M Brummond

J Med Chem· February 2017

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Alkyne Ligation Handles: Propargylation of Hydroxyl, Sulfhydryl, Amino, and Carboxyl Groups via the Nicholas Reaction.
Sarah M Wells, John C Widen, Daniel A Harki, Kay M Brummond

Org Lett· September 2016

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Mechanistic Insight into the Dehydro-Diels-Alder Reaction of Styrene-Ynes.
Laura S Kocsis, Husain N Kagalwala, Sharlene Mutto, Bhaskar Godugu, Stefan Bernhard, Kay M Brummond

J Org Chem· December 2015

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Intramolecular didehydro-Diels-Alder reaction and its impact on the structure-function properties of environmentally sensitive fluorophores.
Kay M Brummond, Laura S Kocsis

Acc Chem Res· August 2015

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Conditions for a Rh(I)-catalyzed [2 + 2 + 1] cycloaddition reaction with methyl substituted allenes and alkynes.
Sarah M Wells, Kay M Brummond

Tetrahedron Lett· June 2015

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Cyclopenta[b]naphthalene cyanoacrylate dyes: synthesis and evaluation as fluorescent molecular rotors.
Laura S Kocsis, Kristyna M Elbel, Billie A Hardigree, Kay M Brummond, Mark A Haidekker

Org Biomol Chem· March 2015

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Identification of ATR-Chk1 pathway inhibitors that selectively target p53-deficient cells without directly suppressing ATR catalytic activity.
Masaoki Kawasumi, James E Bradner, Nicola Tolliday, Renee Thibodeau, Heather Sloan, Kay M Brummond

Cancer Res· December 2014

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Intramolecular dehydro-Diels-Alder reaction affords selective entry to arylnaphthalene or aryldihydronaphthalene lignans.
Laura S Kocsis, Kay M Brummond

Org Lett· August 2014

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Attachable solvatochromic fluorophores and bioconjugation studies.
Erica Benedetti, Andrea B E Veliz, Mélanie Charpenay, Laura S Kocsis, Kay M Brummond

Org Lett· June 2013

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