Publications by authors named "Kazuma Sekiba"

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CRISPR-mediated proximity labeling unveils ABHD14B as a host factor to regulate HBV cccDNA transcriptional activity.
Kazuma Sekiba, Nozomi Miyake, Yu Miyakawa, Chikako Shibata, Takahiro Seimiya

Hepatol Commun· August 2025

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Satellite double-stranded RNA induces mesenchymal transition in pancreatic cancer by regulating alternative splicing.
Takuma Iwata, Takahiro Kishikawa, Takahiro Seimiya, Genso Notoya, Tatsunori Suzuki, Kazuma Sekiba

J Biol Chem· March 2024

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A small molecule iCDM-34 identified by in silico screening suppresses HBV DNA through activation of aryl hydrocarbon receptor.
Yutaka Furutani, Yoshinori Hirano, Mariko Toguchi, Shoko Higuchi, Xian-Yang Qin, Kazuma Sekiba

Cell Death Discov· December 2023

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Cabozantinib inhibits HBV-RNA transcription by decreasing STAT3 binding to the enhancer region of cccDNA.
Kazuyoshi Funato, Nozomi Miyake, Kazuma Sekiba, Yu Miyakawa, Takahiro Seimiya

Hepatol Commun· November 2023

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A widely distributed gene cluster compensates for uricase loss in hominids.
Yuanyuan Liu, J Bryce Jarman, Yen S Low, Hannah E Augustijn, Steven Huang, Kazuma Sekiba

Cell· September 2023

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A widely distributed gene cluster compensates for uricase loss in hominids.
Yuanyuan Liu, J Bryce Jarman, Yen S Low, Hannah E Augustijn, Steven Huang, Kazuma Sekiba

Cell· August 2023

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Combination of serum human satellite RNA and miR-21-5p levels as a biomarker for pancreatic cancer.
Takahiro Seimiya, Tatsunori Suzuki, Takuma Iwata, Takahiro Kishikawa, Kazuma Sekiba

iScience· February 2023

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The RNA-Binding Protein ELAVL1 Regulates Hepatitis B Virus Replication and Growth of Hepatocellular Carcinoma Cells.
Hiroaki Kanzaki, Tetsuhiro Chiba, Tatsuya Kaneko, Junjie Ao, Motoyasu Kan, Kazuma Sekiba

Int J Mol Sci· July 2022

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Hepatitis B virus-associated hepatocellular carcinoma with Smc5/6 complex deficiency is susceptible to PARP inhibitors.
Kazuyoshi Funato, Motoyuki Otsuka, Kazuma Sekiba, Yu Miyakawa, Takahiro Seimiya

Biochem Biophys Res Commun· June 2022

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Mutant KRAS drives metabolic reprogramming and autophagic flux in premalignant pancreatic cells.
Tatsunori Suzuki, Takahiro Kishikawa, Tatsuyuki Sato, Norihiko Takeda, Yuki Sugiura, Kazuma Sekiba

Cancer Gene Ther· May 2022

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HBx-induced degradation of Smc5/6 complex impairs homologous recombination-mediated repair of damaged DNA.
Kazuma Sekiba, Motoyuki Otsuka, Kazuyoshi Funato, Yu Miyakawa, Eri Tanaka

J Hepatol· January 2022

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Humanized virus-suppressing factor inhibits hepatitis B virus infection by targeting viral cell entry.
Yu Miyakawa, Motoyuki Otsuka, Kazuma Sekiba, Kazuyoshi Funato, Kazuhiko Koike

Heliyon· July 2021

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Potential of HBx Gene for Hepatocarcinogenesis in Noncirrhotic Liver.
Kazuma Sekiba, Motoyuki Otsuka, Kazuhiko Koike

Semin Liver Dis· May 2021

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Aberrant expression of a novel circular RNA in pancreatic cancer.
Takahiro Seimiya, Motoyuki Otsuka, Takuma Iwata, Eri Tanaka, Kazuma Sekiba

J Hum Genet· February 2021

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A single nucleotide polymorphism in is associated with endoscopic grading in Kyoto classification of gastritis.
Osamu Toyoshima, Toshihiro Nishizawa, Kazuma Sekiba, Tatsuya Matsuno, Ryo Kondo

J Clin Biochem Nutr· January 2021

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The simplified Kyoto classification score is consistent with the ABC method of classification as a grading system for endoscopic gastritis.
Toshihiro Nishizawa, Osamu Toyoshima, Ryo Kondo, Kazuma Sekiba, Yosuke Tsuji

J Clin Biochem Nutr· January 2021

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The fatty-acid amide hydrolase inhibitor URB597 inhibits MICA/B shedding.
Kazuma Sekiba, Motoyuki Otsuka, Takahiro Seimiya, Eri Tanaka, Kazuyoshi Funato

Sci Rep· September 2020

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Expert endoscopists with high adenoma detection rates frequently detect diminutive adenomas in proximal colon.
Osamu Toyoshima, Toshihiro Nishizawa, Shuntaro Yoshida, Kazuma Sekiba, Yosuke Kataoka

Endosc Int Open· June 2020

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Detection of circulating colorectal cancer cells by a custom microfluid system before and after endoscopic metallic stent placement.
Rei Ishibashi, Shuntaro Yoshida, Nariaki Odawara, Takahiro Kishikawa, Ryo Kondo, Kazuma Sekiba

Oncol Lett· December 2019

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Identifying Inhibitors of the HBx-DDB1 Interaction Using a Split Luciferase Assay System.
Kazuma Sekiba, Motoyuki Otsuka, Kazuhiko Koike

J Vis Exp· December 2019

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Expression of circular RNA CDR1‑AS in colon cancer cells increases cell surface PD‑L1 protein levels.
Eri Tanaka, Yu Miyakawa, Takahiro Kishikawa, Takahiro Seimiya, Takuma Iwata, Kazuma Sekiba

Oncol Rep· October 2019

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Pevonedistat, a Neuronal Precursor Cell-Expressed Developmentally Down-Regulated Protein 8-Activating Enzyme Inhibitor, Is a Potent Inhibitor of Hepatitis B Virus.
Kazuma Sekiba, Motoyuki Otsuka, Motoko Ohno, Mari Yamagami, Takahiro Kishikawa

Hepatology· May 2019

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Inhibition of HBV Transcription From cccDNA With Nitazoxanide by Targeting the HBx-DDB1 Interaction.
Kazuma Sekiba, Motoyuki Otsuka, Motoko Ohno, Mari Yamagami, Takahiro Kishikawa

Cell Mol Gastroenterol Hepatol· May 2019

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Inflammation and de-differentiation in pancreatic carcinogenesis.
Takahiro Seimiya, Motoyuki Otsuka, Takuma Iwata, Eri Tanaka, Tatsunori Suzuki, Kazuma Sekiba

World J Clin Cases· December 2018

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ISGF3 with reduced phosphorylation is associated with constitutive expression of interferon-induced genes in aging cells.
Mari Yamagami, Motoyuki Otsuka, Takahiro Kishikawa, Kazuma Sekiba, Takahiro Seimiya

NPJ Aging Mech Dis· November 2018

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