Publications by authors named "Keguang Cheng"

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Genomic insights into the evolutionary history and conservation of the living fossil .
Zhao-Yang Jing, Ren-Gang Zhang, Yang Liu, Ke-Guang Cheng, De-Tuan Liu

Plant Divers· September 2025

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Photocatalytic C-H Trifluoroethoxylation of (Hetero)arenes.
Mingxi Chen, Jingjing Ling, Keguang Cheng, Quande Wang

Org Lett· March 2025

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Research progress on GPX4 targeted compounds.
Bingru Li, Keguang Cheng, Tzumei Wang, Xing Peng, Ping Xu

Eur J Med Chem· August 2024

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6-O-angeloylplenolin inhibits osteoclastogenesis in vitro via suppressing c-Src/NF-κB/NFATc1 pathways and ameliorates bone resorption in collagen-induced arthritis mouse model.
Zhi-Chao Li, Min Li, Ling-Xiang Xiao, Xi Zheng, Rong Li, Ke-Guang Cheng

Biochem Pharmacol· June 2024

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Radical Acylfluoroalkylation of 1,3-Enynes via -Heterocyclic Carbene/Photoredox Cooperative Catalysis.
Shichao Tian, Ning Chen, Keguang Cheng, Quande Wang

Org Lett· May 2024

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N-Heterocyclic Carbene and Manganese Synergistic Catalysis: A Three-Component Radical Acylmonofluoroalkylation of Alkenes.
Feng Liang, Ning Chen, Keguang Cheng, Quande Wang

Org Lett· November 2023

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Pentacyclic triterpene-amino acid derivatives induced apoptosis and autophagy in tumor cells, affected the JNK and PI3K/AKT/mTOR pathway.
Li-Qiong Zhang, Li Sun, Yu-Qing Zhou, Jing-Jing Liu, Quan-de Wang, Ke-Guang Cheng

Bioorg Med Chem· October 2023

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Rapid Formation of Intramolecular Disulfide Bridges using Light: An Efficient Method to Control the Conformation and Function of Bioactive Peptides.
Feng He, Yu Chai, Zizhen Zeng, Fangling Lu, Huanwen Chen, Keguang Cheng

J Am Chem Soc· October 2023

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Pyrazolone derivatives as potent and selective small-molecule SIRT5 inhibitors.
Jian Yao, Yudong Yin, Hong Han, Shaoting Chen, Yuxiang Zheng, Keguang Cheng

Eur J Med Chem· February 2023

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(4-Picolylamino)-17β-Estradiol derivative and analogues induce apoptosis with death receptor trail R2/DR5 in MCF-7.
Yudong Yin, Li Sun, Lixin Sheng, Liqiong Zhang, Jingjing Liu, Keguang Cheng

Chem Biol Interact· January 2023

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Synthesis and in vitro/in vivo anticancer evaluation of pentacyclic triterpenoid derivatives linked with l-phenylalanine or l-proline.
Yudong Yin, Lixin Sheng, Juzheng Zhang, Liqiong Zhang, Jingjing Liu, Keguang Cheng

Bioorg Chem· September 2022

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Discovery of the First Selective Nanomolar Inhibitors of ERAP2 by Kinetic Target-Guided Synthesis.
Virgyl Camberlein, Charlotte Fléau, Pierre Sierocki, Lenong Li, Ronan Gealageas, Keguang Cheng

Angew Chem Int Ed Engl· September 2022

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Spectrum-Effect Relationship Analysis of Bioactive Compounds in (Roxb.) DC. by Ultra-High Performance Liquid Chromatography Mass Spectrometry Coupled With Comprehensive Filtering Approaches.
Si-Wei Rao, Yuan-Yuan Duan, Han-Qing Pang, Shao-Hua Xu, Shou-Qian Hu, Ke-Guang Cheng

Front Pharmacol· March 2022

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Discovery of Novel Small Molecule Inhibitors Disrupting the PCSK9-LDLR Interaction.
Hengzhi Sun, Jinzheng Wang, Shengjie Liu, Xinyu Zhou, Liang Dai, Keguang Cheng

J Chem Inf Model· October 2021

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New possible silver lining for pancreatic cancer therapy: Hydrogen sulfide and its donors.
Xu Hu, Yan Xiao, Jianan Sun, Bao Ji, Shanshan Luo, Keguang Cheng

Acta Pharm Sin B· May 2021

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Synthesis and anti-inflammatory activity of saponin derivatives of δ-oleanolic acid.
Liu Liu, Haobin Li, Kaiwen Hu, Qinglong Xu, Xiaoan Wen, Keguang Cheng

Eur J Med Chem· January 2021

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Renieramycin-type alkaloids from marine-derived organisms: Synthetic chemistry, biological activity and structural modification.
Yuxi Fang, Haonan Li, Bao Ji, Keguang Cheng, Bo Wu

Eur J Med Chem· January 2021

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N-benzylpiperidinol derivatives as novel USP7 inhibitors: Structure-activity relationships and X-ray crystallographic studies.
Minglei Li, Shengjie Liu, Hui Chen, Xinyu Zhou, Jin Zhou, Keguang Cheng

Eur J Med Chem· August 2020

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Discovery of AdipoRon analogues as novel AMPK activators without inhibiting mitochondrial complex I.
Geng Sun, Yanping You, Haobin Li, Yalong Cheng, Ming Qian, Keguang Cheng

Eur J Med Chem· August 2020

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Development of Therapeutic Gramicidin S Analogues Bearing Plastic β,γ-Diamino Acids.
Qinkun Guan, Kaisen Chen, Qiang Chen, Jianguo Hu, Keguang Cheng, Chengfei Hu

ChemMedChem· June 2020

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Discovery of Ubiquitin-Specific Protease 7 (USP7) Inhibitors with Novel Scaffold Structures by Virtual Screening, Molecular Dynamics Simulation, and Biological Evaluation.
Shengjie Liu, Xinyu Zhou, Minglei Li, Wenfeng Zhao, Shuxi Zhou, Keguang Cheng

J Chem Inf Model· June 2020

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Discovery of Novel Peroxisome Proliferator-Activated Receptor α (PPARα) Agonists by Virtual Screening and Biological Evaluation.
Liang Dai, Zhiqi Feng, Rili Zha, Keguang Cheng, Xiaoan Wen

J Chem Inf Model· March 2020

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Design, synthesis and apoptosis-related antiproliferative activities of chelidonine derivatives.
Xueyan Huang, Keguang Cheng, Lilin Liu, Xu Hu, Xiang Gao

Bioorg Med Chem Lett· February 2020

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Design, Synthesis, and Evaluation of Novel 2-Methoxyestradiol Derivatives as Apoptotic Inducers Through an Intrinsic Apoptosis Pathway.
Li-Xin Sheng, Jiang-Yu Zhang, Li Li, Xiao Xie, Xiao-An Wen, Ke-Guang Cheng

Biomolecules· January 2020

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Synthesis and antitumor activity of fluorouracil - oleanolic acid/ursolic acid/glycyrrhetinic acid conjugates.
Chun-Mei Liu, Jia-Yan Huang, Li-Xin Sheng, Xiao-An Wen, Ke-Guang Cheng

Medchemcomm· August 2019

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