Publications by authors named "Keigo Okada"

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Favorable response to daratumumab combination therapy in patients with multiple myeloma with an immature phenotype: a report from the J-CHARGE study group.
Noriyoshi Iriyama, Hitomi Nakayama, Masaru Nakagawa, Atsushi Takahata, Eriko Sato, Keigo Okada

Int J Hematol· November 2025

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Investigation of early mortality in the patients with newly diagnosed multiple myeloma: insights from a real-world cohort using J-CHAEGE-MM database.
Michihide Tokuhira, Hitomi Nakayama, Kohtaro Toyama, Motoki Takano, Noriyoshi Iriyama, Keigo Okada

Int J Hematol· October 2025

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Clinical factors for central nervous system progression and survival in primary vitreoretinal lymphoma.
Yotaro Motomura, Kota Yoshifuji, Takayoshi Tachibana, Hiroshi Takase, Ayako Arai, Keigo Okada

Br J Haematol· April 2024

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[Acute promyelocytic leukemia with asymptomatic cerebral hemorrhage].
Satoshi Koi, Ayako Nogami, Hiroki Fujiwara, Kana Bando, Makiko Saito, Keigo Okada

Rinsho Ketsueki· December 2023

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Lymphoproliferative disorder risk after methotrexate treatment for rheumatoid arthritis.
Keisuke Tanaka, Ayako Ichikawa, Natsuka Umezawa, Kouhei Yamamoto, Kota Yoshifuji, Keigo Okada

Cancer Sci· September 2023

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Impact of standard-dose dipeptidyl peptidase-4 inhibitors on the incidence of graft-versus-host disease after allogeneic hematopoietic cell transplantation.
Shun-Ichi Kimura, Hiroaki Shimizu, Takuya Miyazaki, Masatoshi Sakurai, Susumu Tanoue, Keigo Okada

Bone Marrow Transplant· April 2023

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[Relationship between Left Ventricle Myocardium Volume in Coronary Territories' Analysis and Fractional Flow Reserve].
Manabu Shoji, Daisuke Kittaka, Keigo Okada, Mitsuyoshi Yasuda, Hiroyuki Watanabe

Nihon Hoshasen Gijutsu Gakkai Zasshi· May 2022

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[Perioperative management of laparoscopic cholecystectomy in a patient with paroxysmal nocturnal haemoglobinuria undergoing ravulizumab treatment].
Moyu Kimura, Yu Nishiyama, Hiroki Ueda, Akiko Kitajo, Tomoyuki Arimatsu, Keigo Okada

Rinsho Ketsueki· May 2022

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A novel chimeric antigen receptor (CAR) system using an exogenous protease, in which activation of T cells is controlled by expression patterns of cell‑surface proteins on target cells.
Satoru Aoyama, Shunichiro Yasuda, Huixin Li, Daisuke Watanabe, Yoshihiro Umezawa, Keigo Okada

Int J Mol Med· April 2022

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Successful treatment with bortezomib for refractory fever associated with myelodysplastic syndrome with underlying lymphoplasmacytic lymphoma.
Yotaro Motomura, Yoshihiro Umezawa, Tomoyuki Arimatsu, Keigo Okada, Osamu Miura

Clin Case Rep· February 2022

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Severe Motor Weakness Due to Disturbance in Peripheral Nerves Following Tisagenlecleucel Treatment.
Mai Kuboki, Yoshihiro Umezawa, Yotaro Motomura, Keigo Okada, Ayako Nogami

In Vivo· October 2021

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An Antibody-Drug Conjugate That Selectively Targets Human Monocyte Progenitors for Anti-Cancer Therapy.
Yuta Izumi, Masashi Kanayama, Zhongchuzi Shen, Masayuki Kai, Shunsuke Kawamura, Keigo Okada

Front Immunol· July 2021

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Efficacy and Safety of Balloon Kyphoplasty for Pathological Vertebral Fractures in Patients with Hematological Malignancies in Our Institution.
Keigo Okada, Hiroki Fujiwara, Tomoyuki Arimatsu, Yotaro Motomura, Tsuyoshi Kato

Intern Med· April 2021

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Inhibition of USP9X Downregulates JAK2-V617F and Induces Apoptosis Synergistically with BH3 Mimetics Preferentially in Ruxolitinib-Persistent JAK2-V617F-Positive Leukemic Cells.
Hiroki Akiyama, Yoshihiro Umezawa, Daisuke Watanabe, Keigo Okada, Shinya Ishida

Cancers (Basel)· February 2020

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FLT3-ITD Activates RSK1 to Enhance Proliferation and Survival of AML Cells by Activating mTORC1 and eIF4B Cooperatively with PIM or PI3K and by Inhibiting Bad and BIM.
Daisuke Watanabe, Ayako Nogami, Keigo Okada, Hiroki Akiyama, Yoshihiro Umezawa

Cancers (Basel)· November 2019

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Inhibition of USP9X induces apoptosis in FLT3-ITD-positive AML cells cooperatively by inhibiting the mutant kinase through aggresomal translocation and inducing oxidative stress.
Hiroki Akiyama, Yoshihiro Umezawa, Shinya Ishida, Keigo Okada, Ayako Nogami

Cancer Lett· July 2019

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Inhibition of the STAT5/Pim Kinase Axis Enhances Cytotoxic Effects of Proteasome Inhibitors on FLT3-ITD-Positive AML Cells by Cooperatively Inhibiting the mTORC1/4EBP1/S6K/Mcl-1 Pathway.
Ayako Nogami, Keigo Okada, Shinya Ishida, Hiroki Akiyama, Yoshihiro Umezawa

Transl Oncol· February 2019

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[Surgical Treatment Outcome of Patients with Colorectal Cancer Having Ulcerative Colitis].
Motoi Koyama, Ayato Obana, Norio Mizuguchi, Kenta Kitamura, Tomonori Matsumura, Keigo Okada

Gan To Kagaku Ryoho· December 2018

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[A Case of Metachronous Ascending Colon Metastasis from Gastric Cancer That Was Difficult to Diagnose].
Norio Mizuguchi, Motoi Koyama, Ayato Obana, Kenta Kitamura, Tomonori Matsumura, Keigo Okada

Gan To Kagaku Ryoho· December 2018

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Mechanisms for mTORC1 activation and synergistic induction of apoptosis by ruxolitinib and BH3 mimetics or autophagy inhibitors in JAK2-V617F-expressing leukemic cells including newly established PVTL-2.
Shinya Ishida, Hiroki Akiyama, Yoshihiro Umezawa, Keigo Okada, Ayako Nogami

Oncotarget· June 2018

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FLT3-ITD induces expression of Pim kinases through STAT5 to confer resistance to the PI3K/Akt pathway inhibitors on leukemic cells by enhancing the mTORC1/Mcl-1 pathway.
Keigo Okada, Ayako Nogami, Shinya Ishida, Hiroki Akiyama, Cheng Chen

Oncotarget· February 2018

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Molecular mechanisms for enhancement of stromal cell-derived factor 1-induced chemotaxis by platelet endothelial cell adhesion molecule 1 (PECAM-1).
Yoshihiro Umezawa, Hiroki Akiyama, Keigo Okada, Shinya Ishida, Ayako Nogami

J Biol Chem· December 2017

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[Assessment of Long-Term Sexual Function after Radical Resection for Lower Rectal Cancer].
Motoi Koyama, Keigo Okada, Kenta Kitamura, Tomonori Matsumura, Eishi Totsuka

Gan To Kagaku Ryoho· November 2017

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[Assessment of Functional Results after Sphincter-Preserving Surgery in Elderly Patients with Low Rectal Cancer].
Motoi Koyama, Kenta Kitamura, Tomonori Matsumura, Keigo Okada, Satoshi Inose

Gan To Kagaku Ryoho· November 2016

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[Regrowth of Isolated Local Residual Tumor Effectively Treated with Chemoradiotherapy More Than Five Years after a Resection for Pancreatic Cancer with an Involvement of the Portal Vein].
Tomonori Matsumura, Eishi Totsuka, Kenta Kitamura, Keigo Okada, Satoshi Inose

Gan To Kagaku Ryoho· November 2016

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