Publications by authors named "Keith A Spriggs"

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Retraction: Translational reprogramming following UVB irradiation is mediated by DNA-PKcs and allows selective recruitment to the polysomes of mRNAs encoding DNA repair enzymes.
Ian R Powley, Alexander Kondrashov, Lucy A Young, Helen C Dobbyn, Kirsti Hill, Keith A Spriggs

Genes Dev· June 2025

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Antiproliferative activities of some selected Nigerian medicinal plants against breast, liver, and cervical cancer cells.
Olubusola O Olaleye, Dong-Hyun Kim, Keith A Spriggs

BMC Complement Med Ther· March 2024

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Implications of differential transcription start site selection on chronic myeloid leukemia and prostate cancer cell protein expression.
Arif A Surani, Keith A Spriggs, Christoph Ufer, Christos Polytarchou, Cristina Montiel-Duarte

iScience· December 2022

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Correction to 'The human insulin receptor mRNA contains a functional internal ribosome entry segment'.
Keith A Spriggs, Laura C Cobbold, Simon H Ridley, Mark Coldwell, Andrew Bottley

Nucleic Acids Res· February 2022

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Water Solubility Enhancement of Pyrazolo[3,4-]pyrimidine Derivatives via Miniaturized Polymer-Drug Microarrays.
Monica Sanna, Giovanna Sicilia, Ali Alazzo, Nishant Singh, Francesca Musumeci, Keith A Spriggs

ACS Med Chem Lett· March 2018

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Correction: PRAME Is a Golgi-Targeted Protein That Associates with the Elongin BC Complex and Is Upregulated by Interferon-Gamma and Bacterial PAMPs.
Frances R Wadelin, Joel Fulton, Hilary M Collins, Nikolaos Tertipis, Andrew Bottley, Keith A Spriggs

PLoS One· September 2015

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PRAME is a golgi-targeted protein that associates with the Elongin BC complex and is upregulated by interferon-gamma and bacterial PAMPs.
Frances R Wadelin, Joel Fulton, Hilary M Collins, Nikolaos Tertipis, Andrew Bottley, Keith A Spriggs

PLoS One· September 2013

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Translational regulation of gene expression during conditions of cell stress.
Keith A Spriggs, Martin Bushell, Anne E Willis

Mol Cell· October 2010

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eIF4A inhibition allows translational regulation of mRNAs encoding proteins involved in Alzheimer's disease.
Andrew Bottley, Nicola M Phillips, Thomas E Webb, Anne E Willis, Keith A Spriggs

PLoS One· September 2010

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Leucine-rich repeat protein PRAME: expression, potential functions and clinical implications for leukaemia.
Frances Wadelin, Joel Fulton, Paul A McEwan, Keith A Spriggs, Jonas Emsley

Mol Cancer· August 2010

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Dysregulation of protein synthesis and disease.
John P C Le Quesne, Keith A Spriggs, Martin Bushell, Anne E Willis

J Pathol· January 2010

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Co-ordinated regulation of translation following DNA damage.
Alexander V Kondrashov, Keith A Spriggs, Martin Bushell, Anne E Willis

Cell Cycle· October 2009

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The human insulin receptor mRNA contains a functional internal ribosome entry segment.
Keith A Spriggs, Laura C Cobbold, Simon H Ridley, Mark Coldwell, Andrew Bottley

Nucleic Acids Res· September 2009

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Translational reprogramming following UVB irradiation is mediated by DNA-PKcs and allows selective recruitment to the polysomes of mRNAs encoding DNA repair enzymes.
Ian R Powley, Alexander Kondrashov, Lucy A Young, Helen C Dobbyn, Kirsti Hill, Keith A Spriggs

Genes Dev· May 2009

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Canonical initiation factor requirements of the Myc family of internal ribosome entry segments.
Keith A Spriggs, Laura C Cobbold, Catherine L Jopling, Rebecca E Cooper, Lindsay A Wilson

Mol Cell Biol· March 2009

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Polypyrimidine-tract-binding protein: a multifunctional RNA-binding protein.
Kirsty Sawicka, Martin Bushell, Keith A Spriggs, Anne E Willis

Biochem Soc Trans· August 2008

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The mechanism of micro-RNA-mediated translation repression is determined by the promoter of the target gene.
Yi Wen Kong, Ian G Cannell, Cornelia H de Moor, Kirsti Hill, Paul G Garside, Keith A Spriggs

Proc Natl Acad Sci U S A· July 2008

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SF2/ASF TORCs up translation.
Martin Bushell, Mark Stoneley, Keith A Spriggs, Anne E Willis

Mol Cell· May 2008

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Identification of internal ribosome entry segment (IRES)-trans-acting factors for the Myc family of IRESs.
Laura C Cobbold, Keith A Spriggs, Stephen J Haines, Helen C Dobbyn, Christopher Hayes

Mol Cell Biol· January 2008

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Re-programming of translation following cell stress allows IRES-mediated translation to predominate.
Keith A Spriggs, Mark Stoneley, Martin Bushell, Anne E Willis

Biol Cell· January 2008

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Polypyrimidine tract binding protein regulates IRES-mediated gene expression during apoptosis.
Martin Bushell, Mark Stoneley, Yi Wen Kong, Tiffany L Hamilton, Keith A Spriggs

Mol Cell· August 2006

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Identification of a motif that mediates polypyrimidine tract-binding protein-dependent internal ribosome entry.
Sally A Mitchell, Keith A Spriggs, Martin Bushell, Joanne R Evans, Mark Stoneley, Ruth V Spriggs

Genes Dev· July 2005

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Bag-1 internal ribosome entry segment activity is promoted by structural changes mediated by poly(rC) binding protein 1 and recruitment of polypyrimidine tract binding protein 1.
Becky M Pickering, Sally A Mitchell, Keith A Spriggs, Mark Stoneley, Anne E Willis

Mol Cell Biol· June 2004

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L-Myc protein synthesis is initiated by internal ribosome entry.
Catherine L Jopling, Keith A Spriggs, Sally A Mitchell, Mark Stoneley, Anne E Willis

RNA· February 2004

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Members of the poly (rC) binding protein family stimulate the activity of the c-myc internal ribosome entry segment in vitro and in vivo.
Joanne R Evans, Sally A Mitchell, Keith A Spriggs, Jerzy Ostrowski, Karol Bomsztyk

Oncogene· September 2003

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