Publications by authors named "Keith Abrams"

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Evaluating amyloid-beta as a surrogate endpoint in trials of anti-amyloid-beta drugs in Alzheimer's disease: a Bayesian meta-analysis.
Sa Ren, Janharpreet Singh, Sandro Gsteiger, Christopher Cogley, Ben Reed, Keith R Abrams

J Comp Eff Res· January 2026

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Efficacy and safety of treatments for metastatic castration-sensitive prostate cancer: A comprehensive network meta-analysis including final ARANOTE data.
Neal Shore, Alicia K Morgans, Noman Paracha, Elaine Gallagher, Howard Thom, Keith R Abrams

Prostate Cancer Prostatic Dis· December 2025

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Considerations driving the choice in clinical trial design of cell and gene therapy products: weighing convenience versus necessity.
Keith Abrams, Alessandro Aiuti, Hans-Georg Eichler, Andreas Ziegler

Cytotherapy· October 2025

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Cure Models: What is Meant by a Survival 'Plateau', and Do Experts Agree on What Constitutes One?
Dan Jackson, Michael Sweeting, Robert Hettle, Binbing Yu, Neil Hawkins, Keith Abrams

Pharmacoeconomics· October 2025

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Clinical Benefit From Molecularly Guided Cancer Care: A Matching-Adjusted Indirect Comparison of Larotrectinib Versus Standard of Care.
Carsten Bokemeyer, Keith R Abrams, Jesus Garcia-Foncillas, Antoine Italiano, Ulrik Lassen

JCO Precis Oncol· September 2025

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Radiological progression-free survival as a surrogate for overall survival in patients with metastatic hormone-sensitive prostate cancer: A bivariate meta-analysis.
Neal Shore, Alicia K Morgans, Martin Boegemann, Elaine Gallagher, Noman Paracha, Keith R Abrams

Eur J Cancer· June 2025

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A New Frequentist Implementation of the Daniels and Hughes Bivariate Meta-Analysis Model for Surrogate Endpoint Evaluation.
Dan Jackson, Michael Sweeting, Robbie C M van Aert, Sylwia Bujkiewicz, Keith R Abrams

Biom J· April 2025

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Advancing the role of real-world evidence in comparative effectiveness research.
Monica Daigl, Seye Abogunrin, Felipe Castro, Sarah F McGough, Rachele Hendricks Sturrup, Keith R Abrams

J Comp Eff Res· December 2024

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Direct and indirect effects of the COVID-19 pandemic on mortality: an individual-level population-scale analysis using linked electronic health records, Wales, United Kingdom, 2016 to 2022.
Rhiannon K Owen, James D van Oppen, Jane Lyons, Ashley Akbari, Gareth Davies, Keith R Abrams

Euro Surveill· December 2024

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Factors Associated With Early Motor Function Trajectories in DMD After Glucocorticoid Initiation: Post Hoc Analysis of the FOR-DMD Trial.
Marianela Schiava, Michael P McDermott, Jonathan Broomfield, Keith R Abrams, Anna G Mayhew

Neurology· May 2024

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Transporting Comparative Effectiveness Evidence Between Countries: Considerations for Health Technology Assessments.
Alex J Turner, Cormac Sammon, Nick Latimer, Blythe Adamson, Brennan Beal, Keith R Abrams

Pharmacoeconomics· February 2024

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Modeling the multi-state natural history of rare diseases with heterogeneous individual patient data: A simulation study.
Jonathan Broomfield, Keith R Abrams, Suzanne Freeman, Nicholas Latimer, Mark J Rutherford

Stat Med· January 2024

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Individual participant data from digital sources informed and improved precision in the evaluation of predictive biomarkers in Bayesian network meta-analysis.
Chinyereugo M Umemneku-Chikere, Lorna Wheaton, Heather Poad, Devleena Ray, Ilse Cuevas Andrade, Keith R Abrams

J Clin Epidemiol· December 2023

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Natural history of Duchenne muscular dystrophy in the United Kingdom: A descriptive study using the Clinical Practice Research Datalink.
Jonathan Broomfield, Keith Abrams, Nick Latimer, Michela Guglieri, Mark Rutherford

Brain Behav· December 2023

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Clustering long-term health conditions among 67728 people with multimorbidity using electronic health records in Scotland.
Adeniyi Francis Fagbamigbe, Utkarsh Agrawal, Amaya Azcoaga-Lorenzo, Briana MacKerron, Eda Bilici Özyiğit, Keith R Abrams

PLoS One· December 2023

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Cost-Effectiveness Analysis of Siltuximab for Australian Public Investment in the Rare Condition Idiopathic Multicentric Castleman Disease.
Francis Shupo, Keith R Abrams, Zanfina Ademi, Grace Wayi-Wayi, Natasa Zibelnik

Pharmacoecon Open· September 2023

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Trajectories in chronic disease accrual and mortality across the lifespan in Wales, UK (2005-2019), by area deprivation profile: linked electronic health records cohort study on 965,905 individuals.
Jane Lyons, Ashley Akbari, Keith R Abrams, Amaya Azcoaga Lorenzo, Thamer Ba Dhafari

Lancet Reg Health Eur· September 2023

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Effect on life expectancy of temporal sequence in a multimorbidity cluster of psychosis, diabetes, and congestive heart failure among 1·7 million individuals in Wales with 20-year follow-up: a retrospective cohort study using linked data.
Rhiannon K Owen, Jane Lyons, Ashley Akbari, Bruce Guthrie, Utkarsh Agrawal, Keith R Abrams

Lancet Public Health· July 2023

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Prognostic Value of Neurotrophic Tyrosine Receptor Kinase Gene Fusions in Solid Tumors for Overall Survival: A Systematic Review and Meta-Analysis.
Ulrik Lassen, Carsten Bokemeyer, Jesus Garcia-Foncillas, Antoine Italiano, Gilles Vassal, Keith Abrams

JCO Precis Oncol· June 2023

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Hierarchical network meta-analysis models for synthesis of evidence from randomised and non-randomised studies.
Humaira Hussein, Keith R Abrams, Laura J Gray, Sumayya Anwer, Sofia Dias

BMC Med Res Methodol· April 2023

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Publisher Correction: Double-counting of populations in evidence synthesis in public health: a call for awareness and future methodological development.
Humaira Hussein, Clareece R Nevill, Anna Mefen, Keith R Abrams, Sylwia Bujkiewicz

BMC Public Health· December 2022

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Use of copula to model within-study association in bivariate meta-analysis of binomial data at the aggregate level: A Bayesian approach and application to surrogate endpoint evaluation.
Tasos Papanikos, John R Thompson, Keith R Abrams, Sylwia Bujkiewicz

Stat Med· November 2022

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Correction: The association between frailty risk and COVID-19-associated all-mortality in hospitalised older people: a national cohort study.
Laia Maynou, Rhiannon Owen, Rob Konstant-Hambling, Towhid Imam, Suzanne Arkill, Keith R Abrams

Eur Geriatr Med· October 2022

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Double-counting of populations in evidence synthesis in public health: a call for awareness and future methodological development.
Humaira Hussein, Clareece R Nevill, Anna Meffen, Keith R Abrams, Sylwia Bujkiewicz

BMC Public Health· September 2022

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Comparative review of pharmacological therapies in individuals with HER2-positive advanced breast cancer with focus on hormone receptor subgroups.
Chinyereugo M Umemneku-Chikere, Olubukola Ayodele, Marta Soares, Sam Khan, Keith Abrams

Front Oncol· August 2022

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