Publications by authors named "Keith Breau"

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Development of Peptide Glucosyltransferase Inhibitors With Comprehensive Coverage Across Clostridioides difficile Toxin B Sub-Types.
Carly M Catella, Sudeep Sarma, Caroline M Hinesley, Corey E Febo, Keith A Breau

Biotechnol Bioeng· November 2025

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Coupling mathematical modeling with a novel human intestinal stem cell system to understand feedback regulation during planar cell polarity.
Keith A Breau, Emma G Dunahey, Henry V Fosnocht, Scott T Magness, Timothy C Elston

bioRxiv· November 2025

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Comparative Approaches for Quantification of Product Yield in the Production of Recombinant Green Fluorescent Protein (GFPuv) Expressed in .
Gabrielle Rusch, Junhyeong Wang, Keith Breau, Katie Kilgour, Gary Gilleskie

bioRxiv· June 2025

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Sex Differences in Colonic Inflammation are Driven by Epithelial-Specific Expression of Estrogen Receptor Alpha.
Guillermo A Pereda, Adrian D Kocinski, Alyssia V Broncano, Sarah K McNeer, Michelle L Raymond, Keith A Breau

Gastro Hep Adv· January 2025

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An in vitro platform for quantifying cell cycle phase lengths in primary human intestinal epithelial cells.
Michael J Cotton, Pablo Ariel, Kaiwen Chen, Vanessa A Walcott, Michelle Dixit, Keith A Breau

Sci Rep· July 2024

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Actinomyces odontolyticus: From Carries to Colorectal Cancer.
Keith A Breau

Cell Mol Gastroenterol Hepatol· April 2024

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Hypoxia Primes Human ISCs for Interleukin-Dependent Rescue of Stem Cell Activity.
Kristina R Rivera, R Jarrett Bliton, Joseph Burclaff, Michael J Czerwinski, Jintong Liu, Keith A Breau

Cell Mol Gastroenterol Hepatol· October 2023

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An in vitro platform for quantifying cell cycle phase lengths in primary human intestinal stem cells.
Michael J Cotton, Pablo Ariel, Kaiwen Chen, Vanessa A Walcott, Michelle Dixit, Keith A Breau

bioRxiv· October 2023

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A leaky human colon model reveals uncoupled apical/basal cytotoxicity in early toxin exposure.
Meryem T Ok, Jintong Liu, R Jarrett Bliton, Caroline M Hinesley, Ekaterina Ellyce T San Pedro, Keith A Breau

Am J Physiol Gastrointest Liver Physiol· April 2023

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A new microphysiological system shows hypoxia primes human ISCs for interleukin-dependent rescue of stem cell activity.
Kristina R Rivera, R Jarrett Bliton, Joseph Burclaff, Michael J Czerwinski, Jintong Liu, Keith A Breau

bioRxiv· February 2023

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A Planar Culture Model of Human Absorptive Enterocytes Reveals Metformin Increases Fatty Acid Oxidation and Export.
Ismael Gomez-Martinez, R Jarrett Bliton, Keith A Breau, Michael J Czerwinski, Ian A Williamson

Cell Mol Gastroenterol Hepatol· July 2022

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Efficient transgenesis and homology-directed gene targeting in monolayers of primary human small intestinal and colonic epithelial stem cells.
Keith A Breau, Meryem T Ok, Ismael Gomez-Martinez, Joseph Burclaff, Nathan P Kohn

Stem Cell Reports· June 2022

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A Proximal-to-Distal Survey of Healthy Adult Human Small Intestine and Colon Epithelium by Single-Cell Transcriptomics.
Joseph Burclaff, R Jarrett Bliton, Keith A Breau, Meryem T Ok, Ismael Gomez-Martinez

Cell Mol Gastroenterol Hepatol· April 2022

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Pathogenic SPTBN1 variants cause an autosomal dominant neurodevelopmental syndrome.
Margot A Cousin, Blake A Creighton, Keith A Breau, Rebecca C Spillmann, Erin Torti

Nat Genet· July 2021

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