Publications by authors named "Keith Brew"

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Thermodynamic and Mechanistic Insights into Coupled Binding and Unwinding of Collagen by Matrix Metalloproteinase 1.
Szymon W Manka, Keith Brew

J Mol Biol· November 2020

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Thermodynamic profiles of the interactions of suramin, chondroitin sulfate, and pentosan polysulfate with the inhibitory domain of TIMP-3.
Timothy Logue, Michelle Lizotte-Waniewski, Keith Brew

FEBS Lett· January 2020

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Reflections on the evolution of the vertebrate tissue inhibitors of metalloproteinases.
Keith Brew

FASEB J· January 2019

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Hypothesis: Metalloproteinase Inhibitors Decrease Risks of Cardiovascular Disease.
Michelle Lizotte-Waniewski, Keith Brew, Charles H Hennekens

J Cardiovasc Pharmacol Ther· July 2016

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Thermodynamic Basis of Selectivity in the Interactions of Tissue Inhibitors of Metalloproteinases N-domains with Matrix Metalloproteinases-1, -3, and -14.
Haiyin Zou, Ying Wu, Keith Brew

J Biol Chem· May 2016

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Structures of complexes of a metal-independent glycosyltransferase GT6 from Bacteroides ovatus with UDP-N-acetylgalactosamine (UDP-GalNAc) and its hydrolysis products.
Tram T K Pham, Brittany Stinson, Nethaji Thiyagarajan, Michelle Lizotte-Waniewski, Keith Brew

J Biol Chem· March 2014

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Structure of a metal-independent bacterial glycosyltransferase that catalyzes the synthesis of histo-blood group A antigen.
Nethaji Thiyagarajan, Tram T K Pham, Brittany Stinson, Amit Sundriyal, Percy Tumbale, Keith Brew

Sci Rep· May 2013

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Phage display of tissue inhibitor of metalloproteinases-2 (TIMP-2): identification of selective inhibitors of collagenase-1 (metalloproteinase 1 (MMP-1)).
Harinath Bahudhanapati, Yingnan Zhang, Sachdev S Sidhu, Keith Brew

J Biol Chem· September 2011

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Entropy increases from different sources support the high-affinity binding of the N-terminal inhibitory domains of tissue inhibitors of metalloproteinases to the catalytic domains of matrix metalloproteinases-1 and -3.
Ying Wu, Shuo Wei, Steven R Van Doren, Keith Brew

J Biol Chem· May 2011

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Family 6 glycosyltransferases in vertebrates and bacteria: inactivation and horizontal gene transfer may enhance mutualism between vertebrates and bacteria.
Keith Brew, Percy Tumbale, K Ravi Acharya

J Biol Chem· November 2010

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Reactive-site mutants of N-TIMP-3 that selectively inhibit ADAMTS-4 and ADAMTS-5: biological and structural implications.
Ngee H Lim, Masahide Kashiwagi, Robert Visse, Jonathan Jones, Jan J Enghild, Keith Brew

Biochem J· October 2010

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The tissue inhibitors of metalloproteinases (TIMPs): an ancient family with structural and functional diversity.
Keith Brew, Hideaki Nagase

Biochim Biophys Acta· January 2010

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A new role for TIMP-1 in modulating neurite outgrowth and morphology of cortical neurons.
Adlane Ould-yahoui, Evelyne Tremblay, Oualid Sbai, Lotfi Ferhat, Anne Bernard, Keith Brew

PLoS One· December 2009

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Characterization of a metal-independent CAZy family 6 glycosyltransferase from Bacteroides ovatus.
Percy Tumbale, Keith Brew

J Biol Chem· September 2009

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Crystal structure of alpha-1,3-galactosyltransferase (alpha3GT) in a complex with p-nitrophenyl-beta-galactoside (pNPbetaGal).
Haryati Jamaluddin, Percy Tumbale, Tyrone A Ferns, Nethaji Thiyagarajan, Keith Brew

Biochem Biophys Res Commun· August 2009

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Screening a limited structure-based library identifies UDP-GalNAc-specific mutants of alpha-1,3-galactosyltransferase.
Percy Tumbale, Haryati Jamaluddin, Nethaji Thiyagarajan, K Ravi Acharya, Keith Brew

Glycobiology· December 2008

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Inactivation of N-TIMP-1 by N-terminal acetylation when expressed in bacteria.
Steven R Van Doren, Shuo Wei, Guanghua Gao, Beverly B DaGue, Mark O Palmier, Keith Brew

Biopolymers· November 2008

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Application of topologically constrained mini-proteins as ligands, substrates, and inhibitors.
Janelle L Lauer-Fields, Dmitriy Minond, Keith Brew, Gregg B Fields

Methods Mol Biol· August 2008

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Structural basis of UDP-galactose binding by alpha-1,3-galactosyltransferase (alpha3GT): role of negative charge on aspartic acid 316 in structure and activity.
Percy Tumbale, Haryati Jamaluddin, Nethaji Thiyagarajan, Keith Brew, K Ravi Acharya

Biochemistry· August 2008

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Selective modulation of matrix metalloproteinase 9 (MMP-9) functions via exosite inhibition.
Janelle L Lauer-Fields, John K Whitehead, Shunzi Li, Robert P Hammer, Keith Brew

J Biol Chem· July 2008

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Urokinase directly activates matrix metalloproteinases-9: a potential role in glioblastoma invasion.
Yunge Zhao, Charles E Lyons, Aizhen Xiao, Dennis J Templeton, Qingxiang Amy Sang, Keith Brew

Biochem Biophys Res Commun· May 2008

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Catalytic properties of ADAM12 and its domain deletion mutants.
Jonas Jacobsen, Robert Visse, Hans Peter Sørensen, Jan J Enghild, Keith Brew

Biochemistry· January 2008

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Characterization of human angiogenin variants implicated in amyotrophic lateral sclerosis.
Benedict Crabtree, Nethaji Thiyagarajan, Stephen H Prior, Peter Wilson, Shalini Iyer, Keith Brew

Biochemistry· October 2007

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Tissue inhibitor of metalloproteinases-1 promotes liver metastasis by induction of hepatocyte growth factor signaling.
Charlotte Kopitz, Michael Gerg, Obul Reddy Bandapalli, Dilek Ister, Caroline J Pennington, Keith Brew

Cancer Res· September 2007

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Triple-helical transition state analogues: a new class of selective matrix metalloproteinase inhibitors.
Janelle Lauer-Fields, Keith Brew, John K Whitehead, Shunzi Li, Robert P Hammer

J Am Chem Soc· August 2007

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