Publications by authors named "Keith D Robertson"

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Deciphering the interplay between SETD2 mediated H3K36me3 and RNA N6-methyladenosine in clear cell renal cell carcinoma (ccRCC).
Shafiq Shaikh, Xia Zhao, Ryan T Wagner, Xiaoyu Pan, Ryan A Hlady, Keith D Robertson

Epigenetics· December 2025

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Exploring Glypican-3 targeted CAR-NK treatment and potential therapy resistance in hepatocellular carcinoma.
Lei Yang, Kien Pham, Yibo Xi, Qunfeng Wu, Dongfang Liu, Keith D Robertson

PLoS One· May 2025

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Epigenetic heterogeneity hotspots in human liver disease progression.
Ryan A Hlady, Xia Zhao, Louis Y El Khoury, Ryan T Wagner, Aesis Luna, Keith D Robertson

Hepatology· April 2025

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SETD2 loss-of-function uniquely sensitizes cells to epigenetic targeting of NSD1-directed H3K36 methylation.
Ryan T Wagner, Ryan A Hlady, Xiaoyu Pan, Liguo Wang, Sungho Kim, Keith D Robertson

Genome Biol· February 2025

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Single-cell multiomics reveal divergent effects of DNMT3A- and TET2-mutant clonal hematopoiesis in inflammatory response.
Wazim Mohammed Ismail, Jenna A Fernandez, Moritz Binder, Terra L Lasho, Minsuk Kim, Keith D Robertson

Blood Adv· January 2025

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Acyl-CoA Synthetase Medium-Chain Family Member 5-Mediated Fatty Acid Metabolism Dysregulation Promotes the Progression of Hepatocellular Carcinoma.
Lei Yang, Kien Pham, Yibo Xi, Shaoning Jiang, Keith D Robertson

Am J Pathol· October 2024

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Epigenetic memory of environmental exposures as a mediator of liver disease.
Ryan A Hlady, Keith D Robertson

Hepatology· August 2024

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Impact of NSD1 Alternative Transcripts in Actin Filament Formation and Cellular Division Pathways in Fibroblasts.
Giuseppina Conteduca, Davide Cangelosi, Chiara Baldo, Alessia Arado, Barbara Testa, Keith D Robertson

Genes (Basel)· August 2024

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Histone Modifications and miRNA Perturbations Contribute to Transcriptional Dysregulation of Hypertrophy in Obstructive Hypertrophic Cardiomyopathy.
Ramin Garmany, Surendra Dasari, J Martijn Bos, Evelyn T Kim, David J Tester, Keith D Robertson

bioRxiv· May 2024

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DNA methylation at DLGAP2 and risk for relapse in alcohol dependence during acamprosate treatment.
Fatih Özel, Michela Di Criscio, Diana Ioana Lupu, Daniil Sarkisyan, Ryan A Hlady, Keith D Robertson

Drug Alcohol Depend· March 2024

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SETD2 loss in renal epithelial cells drives epithelial-to-mesenchymal transition in a TGF-β-independent manner.
Tianchu Wang, Ryan T Wagner, Ryan A Hlady, Xiaoyu Pan, Xia Zhao, Keith D Robertson

Mol Oncol· January 2024

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Titration-based normalization of antibody amount improves consistency of ChIP-seq experiments.
Ariel Caride, Jin Sung Jang, Geng-Xian Shi, Sam Lenz, Jian Zhong, Keith D Robertson

BMC Genomics· April 2023

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Extensive intratumor regional epigenetic heterogeneity in clear cell renal cell carcinoma targets kidney enhancers and is associated with poor outcome.
Louis Y El Khoury, Xiaoyu Pan, Ryan A Hlady, Ryan T Wagner, Shafiq Shaikh, Keith D Robertson

Clin Epigenetics· April 2023

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SHP2 inhibition enhances Yes-associated protein-mediated liver regeneration in murine partial hepatectomy models.
Ryan D Watkins, EeeLN H Buckarma, Jennifer L Tomlinson, Chantal E McCabe, Jennifer A Yonkus, Keith D Robertson

JCI Insight· August 2022

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Interferon drives HCV scarring of the epigenome and creates targetable vulnerabilities following viral clearance.
Ryan A Hlady, Xia Zhao, Louis Y El Khoury, Aesis Luna, Kien Pham, Keith D Robertson

Hepatology· April 2022

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Oncogenic gene expression and epigenetic remodeling of cis-regulatory elements in ASXL1-mutant chronic myelomonocytic leukemia.
Moritz Binder, Ryan M Carr, Terra L Lasho, Christy M Finke, Abhishek A Mangaonkar, Keith D Robertson

Nat Commun· March 2022

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CpGtools: a python package for DNA methylation analysis.
Ting Wei, Jinfu Nie, Nicholas B Larson, Zhenqing Ye, Jeanette E Eckel-Passow, Keith D Robertson

Bioinformatics· July 2021

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Distinguishing Active Versus Passive DNA Demethylation Using Illumina MethylationEPIC BeadChip Microarrays.
Rochelle L Tiedemann, Hope E Eden, Zhijun Huang, Keith D Robertson, Scott B Rothbart

Methods Mol Biol· June 2021

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RAS mutations drive proliferative chronic myelomonocytic leukemia via a KMT2A-PLK1 axis.
Ryan M Carr, Denis Vorobyev, Terra Lasho, David L Marks, Ezequiel J Tolosa, Keith D Robertson

Nat Commun· May 2021

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Lipid-induced endothelial vascular cell adhesion molecule 1 promotes nonalcoholic steatohepatitis pathogenesis.
Kunimaro Furuta, Qianqian Guo, Kevin D Pavelko, Jeong-Heon Lee, Keith D Robertson

J Clin Invest· March 2021

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Identification of DNA methylation signatures associated with poor outcome in lower-risk Stage, Size, Grade and Necrosis (SSIGN) score clear cell renal cell cancer.
Louis Y El Khoury, Shuang Fu, Ryan A Hlady, Ryan T Wagner, Liguo Wang, Keith D Robertson

Clin Epigenetics· January 2021

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Genome-wide discovery and validation of diagnostic DNA methylation-based biomarkers for hepatocellular cancer detection in circulating cell free DNA.
Ryan A Hlady, Xia Zhao, Xiaoyu Pan, Ju Dong Yang, Fowsiyo Ahmed, Keith D Robertson

Theranostics· September 2020

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Clinical, molecular, and prognostic correlates of number, type, and functional localization of TET2 mutations in chronic myelomonocytic leukemia (CMML)-a study of 1084 patients.
Giacomo Coltro, Abhishek A Mangaonkar, Terra L Lasho, Christy M Finke, Prateek Pophali, Keith D Robertson

Leukemia· May 2020

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Phenotypic correlates and prognostic outcomes of TET2 mutations in myelodysplastic syndrome/myeloproliferative neoplasm overlap syndromes: A comprehensive study of 504 adult patients.
Giacomo Coltro, Guadalupe Antelo, Terra L Lasho, Christy M Finke, Animesh Pardanani, Keith D Robertson

Am J Hematol· April 2020

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