Publications by authors named "Keith Nehrke"

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Tau clearance reverses touch neuron dysfunction in both young and aged .
Trae A Carroll, Gail Vw Johnson, Keith Nehrke

J Alzheimers Dis· November 2025

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The TWK-26/KCNK3 potassium channel and FLR-4 protein kinase coordinate nutrient absorption in the intestine.
Sarah K Torzone, Trae Carroll, Peter C Breen, Natalie R Cohen, Kaylee N Simmons, Keith W Nehrke

bioRxiv· April 2025

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Tau phosphorylation suppresses oxidative stress-induced mitophagy via FKBP8 receptor modulation.
Michael O Isei, Meredith Crockett, Emily Chen, Joel Rodwell-Bullock, Trae Carroll, Keith Nehrke

PLoS One· January 2025

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Mitochondrial Quality Control in Alzheimer's Disease: Insights from Models.
Upasana Ganguly, Trae Carroll, Keith Nehrke, Gail V W Johnson

Antioxidants (Basel)· November 2024

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Manipulating mitochondrial pyruvate carrier function causes metabolic remodeling in corneal myofibroblasts that ameliorates fibrosis.
Kye-Im Jeon, Ankita Kumar, Paul S Brookes, Keith Nehrke, Krystel R Huxlin

Redox Biol· September 2024

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Tau phosphorylation suppresses oxidative stress-induced mitophagy via FKBP8 receptor modulation.
Michael O Isei, Meredith Crockett, Emily Chen, Joel Rodwell-Bullock, Trae Caroll, Keith Nehrke

bioRxiv· July 2024

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Site-specific phosphorylation of tau impacts mitochondrial function and response to stressors.
Michael O Isei, Peter A Girardi, Joel Rodwell-Bullock, Keith Nehrke, Gail V W Johnson

J Neurochem· June 2024

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Blocking Mitochondrial Pyruvate Transport Alters Corneal Myofibroblast Phenotype: A New Target for Treating Fibrosis.
Kye-Im Jeon, Ankita Kumar, Christine L Callan, Margaret DeMagistris, Scott MacRae, Keith Nehrke

Invest Ophthalmol Vis Sci· October 2023

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Site-specific phosphorylation of tau impacts mitochondrial biology and response to stressors.
Michael O Isei, Peter A Girardi, Joel Rodwell-Bullock, Keith Nehrke, Gail Vw Johnson

bioRxiv· February 2023

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Selective disruption of Drp1-independent mitophagy and mitolysosome trafficking by an Alzheimer's disease relevant tau modification in a novel Caenorhabditis elegans model.
Sanjib Guha, Anson Cheng, Trae Carroll, Dennisha King, Shon A Koren, Keith Nehrke

Genetics· August 2022

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Distinct roles for two acid-sensing ion channels in an ultradian clock.
Eva Kaulich, Trae Carroll, Brian D Ackley, Yi-Quan Tang, Iris Hardege, Keith Nehrke

Elife· June 2022

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Defining the Role of Mitochondrial Fission in Corneal Myofibroblast Differentiation.
Kye-Im Jeon, Ankita Kumar, Kaitlin T Wozniak, Keith Nehrke, Krystel R Huxlin

Invest Ophthalmol Vis Sci· April 2022

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FNDC-1-mediated mitophagy and ATFS-1 coordinate to protect against hypoxia-reoxygenation.
Yunki Lim, Brandon Berry, Stephanie Viteri, Matthew McCall, Eun Chan Park, Keith Nehrke

Autophagy· November 2021

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Tau Post-Translational Modifications: Potentiators of Selective Vulnerability in Sporadic Alzheimer's Disease.
Trae Carroll, Sanjib Guha, Keith Nehrke, Gail V W Johnson

Biology (Basel)· October 2021

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The Crosstalk Between Pathological Tau Phosphorylation and Mitochondrial Dysfunction as a Key to Understanding and Treating Alzheimer's Disease.
Sanjib Guha, Gail V W Johnson, Keith Nehrke

Mol Neurobiol· December 2020

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Tauopathy-associated tau modifications selectively impact neurodegeneration and mitophagy in a novel C. elegans single-copy transgenic model.
Sanjib Guha, Sarah Fischer, Gail V W Johnson, Keith Nehrke

Mol Neurodegener· November 2020

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A T231E Mutant that Mimics Pathologic Phosphorylation of Tau in Alzheimer's disease Causes Activation of the Mitochondrial Unfolded Protein Response in touch neurons.
Sanjib Guha, Sarah Fischer, Anson Cheng, Gail V W Johnson, Keith Nehrke

MicroPubl Biol· September 2020

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Semaphorin 3A potentiates the profibrotic effects of transforming growth factor-β1 in the cornea.
Kye-Im Jeon, Keith Nehrke, Krystel R Huxlin

Biochem Biophys Res Commun· January 2020

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Fndc-1 contributes to paternal mitochondria elimination in C. elegans.
Yunki Lim, Karinna Rubio-Peña, Peter J Sobraske, Paola A Molina, Paul S Brookes, Keith Nehrke

Dev Biol· October 2019

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Cardioprotection by the mitochondrial unfolded protein response requires ATF5.
Yves T Wang, Yunki Lim, Matthew N McCall, Kai-Ting Huang, Cole M Haynes, Keith Nehrke

Am J Physiol Heart Circ Physiol· August 2019

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Cardioprotection by nicotinamide mononucleotide (NMN): Involvement of glycolysis and acidic pH.
Sergiy M Nadtochiy, Yves T Wang, Keith Nehrke, Josh Munger, Paul S Brookes

J Mol Cell Cardiol· August 2018

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Cardiac metabolic effects of K1.2 channel deletion and evidence for its mitochondrial localization.
Charles O Smith, Yves T Wang, Sergiy M Nadtochiy, James H Miller, Elizabeth A Jonas, Keith Nehrke

FASEB J· June 2018

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Potential mechanisms linking SIRT activity and hypoxic 2-hydroxyglutarate generation: no role for direct enzyme (de)acetylation.
Sergiy M Nadtochiy, Yves T Wang, Jimmy Zhang, Keith Nehrke, Xenia Schafer

Biochem J· August 2017

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The Slo(w) path to identifying the mitochondrial channels responsible for ischemic protection.
Charles Owen Smith, Keith Nehrke, Paul S Brookes

Biochem J· June 2017

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H(OH), H(OH), H(OH): a holiday perspective. Focus on "Mouse Slc4a11 expressed in Xenopus oocytes is an ideally selective H+/OH- conductance pathway that is stimulated by rises in intracellular and extracellular pH".
Keith Nehrke

Am J Physiol Cell Physiol· December 2016

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