Publications by authors named "Keith Poole"

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Erratum for Lehotsky et al., "Lysine polyphosphate modifications contribute to virulence factors in ".
Kirsten Lehotsky, Nolan Neville, Isabella Martins, Keith Poole, Zongchao Jia

mBio· November 2025

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Lysine polyphosphate modifications contribute to virulence factors in .
Kirsten Lehotsky, Nolan Neville, Isabella Martins, Keith Poole, Zongchao Jia

mBio· May 2025

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The aminoglycoside resistance-promoting AmgRS envelope stress-responsive two-component system in Pseudomonas aeruginosa is zinc-activated and protects cells from zinc-promoted membrane damage.
Keith Poole, Thomas Hay, Christie Gilmour, Michael Fruci

Microbiology (Reading)· May 2019

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Aminoglycoside-inducible expression of the mexAB-oprM multidrug efflux operon in Pseudomonas aeruginosa: Involvement of the envelope stress-responsive AmgRS two-component system.
Michael Fruci, Keith Poole

PLoS One· March 2019

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Structure-guided disruption of the pseudopilus tip complex inhibits the Type II secretion in Pseudomonas aeruginosa.
Yichen Zhang, Frédérick Faucher, Wenwen Zhang, Shu Wang, Nolan Neville, Keith Poole

PLoS Pathog· October 2018

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Meropenem potentiation of aminoglycoside activity against Pseudomonas aeruginosa: involvement of the MexXY-OprM multidrug efflux system.
Keith Poole, Christie Gilmour, Maya A Farha, Michael D Parkins, Rachael Klinoski

J Antimicrob Chemother· May 2018

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Rifampicin potentiation of aminoglycoside activity against cystic fibrosis isolates of Pseudomonas aeruginosa.
Alaya Mikalauskas, Michael D Parkins, Keith Poole

J Antimicrob Chemother· December 2017

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At the Nexus of Antibiotics and Metals: The Impact of Cu and Zn on Antibiotic Activity and Resistance.
Keith Poole

Trends Microbiol· October 2017

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Potentiation of Aminoglycoside Activity in Pseudomonas aeruginosa by Targeting the AmgRS Envelope Stress-Responsive Two-Component System.
Keith Poole, Christie Gilmour, Maya A Farha, Erin Mullen, Calvin Ho-Fung Lau

Antimicrob Agents Chemother· June 2016

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Editorial: Bad Bugs in the XXIst Century: Resistance Mediated by Multi-Drug Efflux Pumps in Gram-Negative Bacteria.
Attilio V Vargiu, Klaas M Pos, Keith Poole, Hiroshi Nikaido

Front Microbiol· June 2016

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Polymyxin Susceptibility in Pseudomonas aeruginosa Linked to the MexXY-OprM Multidrug Efflux System.
Keith Poole, Calvin Ho-Fung Lau, Christie Gilmour, Youai Hao, Joseph S Lam

Antimicrob Agents Chemother· December 2015

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AmgRS-mediated envelope stress-inducible expression of the mexXY multidrug efflux operon of Pseudomonas aeruginosa.
Calvin Ho-Fung Lau, Thomas Krahn, Christie Gilmour, Erin Mullen, Keith Poole

Microbiologyopen· February 2015

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EsrC, an envelope stress-regulated repressor of the mexCD-oprJ multidrug efflux operon in Pseudomonas aeruginosa.
Andrew Purssell, Michael Fruci, Alaya Mikalauskas, Christie Gilmour, Keith Poole

Environ Microbiol· January 2015

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Stress responses as determinants of antimicrobial resistance in Pseudomonas aeruginosa: multidrug efflux and more.
Keith Poole

Can J Microbiol· December 2014

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MexY-promoted aminoglycoside resistance in Pseudomonas aeruginosa: involvement of a putative proximal binding pocket in aminoglycoside recognition.
Calvin Ho-Fung Lau, Daniel Hughes, Keith Poole

mBio· April 2014

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Functional characterization of the NfxB repressor of the mexCD-oprJ multidrug efflux operon of Pseudomonas aeruginosa.
Andrew Purssell, Keith Poole

Microbiology (Reading)· October 2013

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Antibiotic inducibility of the mexXY multidrug efflux operon of Pseudomonas aeruginosa: involvement of the MexZ anti-repressor ArmZ.
Thomas Hay, Sebastien Fraud, Calvin Ho-Fung Lau, Christie Gilmour, Keith Poole

PLoS One· August 2013

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Mutational activation of the AmgRS two-component system in aminoglycoside-resistant Pseudomonas aeruginosa.
Calvin Ho-Fung Lau, Sebastien Fraud, Marcus Jones, Scott N Peterson, Keith Poole

Antimicrob Agents Chemother· May 2013

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Determinants of intrinsic aminoglycoside resistance in Pseudomonas aeruginosa.
Thomas Krahn, Christie Gilmour, Justin Tilak, Sebastien Fraud, Nicholas Kerr, Keith Poole

Antimicrob Agents Chemother· November 2012

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Pseudomonas aeruginosa: resistance to the max.
Keith Poole

Front Microbiol· October 2012

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Reduced expression of the rplU-rpmA ribosomal protein operon in mexXY-expressing pan-aminoglycoside-resistant mutants of pseudomonas aeruginosa.
Calvin Ho-Fung Lau, Sebastien Fraud, Marcus Jones, Scott N Peterson, Keith Poole

Antimicrob Agents Chemother· October 2012

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Bacterial stress responses as determinants of antimicrobial resistance.
Keith Poole

J Antimicrob Chemother· September 2012

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Pentachlorophenol induction of the Pseudomonas aeruginosa mexAB-oprM efflux operon: involvement of repressors NalC and MexR and the antirepressor ArmR.
Lisa M Starr, Michael Fruci, Keith Poole

PLoS One· July 2012

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Stress responses as determinants of antimicrobial resistance in Gram-negative bacteria.
Keith Poole

Trends Microbiol· May 2012

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Effect of multidrug resistance-conferring mutations on the fitness and virulence of Pseudomonas aeruginosa.
Kamilia Abdelraouf, Samer Kabbara, Kimberly R Ledesma, Keith Poole, Vincent H Tam

J Antimicrob Chemother· June 2011

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