Publications by authors named "Keith Youker"

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Single-Cell Splicing Isoform Atlas of the Adult Human Heart and Heart Failure.
Timothy Pan, Lina Lu, Keith Youker, Cheng-Kai Shiau, Minhua Wang

Circulation· November 2025

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Transcription factor 4 maintains endothelial cell identity by inhibiting endothelial to mesenchymal transition.
Gaopeng Xian, Rongbin Zheng, Jie Lv, Sen Zhu, Min Chen, Keith Youker

Nucleic Acids Res· October 2025

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Thor: a platform for cell-level investigation of spatial transcriptomics and histology.
Pengzhi Zhang, Weiqing Chen, Tu N Tran, Minghao Zhou, Kaylee N Carter, Keith Youker

Nat Commun· August 2025

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A visual-omics foundation model to bridge histopathology with spatial transcriptomics.
Weiqing Chen, Pengzhi Zhang, Tu N Tran, Yiwei Xiao, Shengyu Li, Keith Youker

Nat Methods· July 2025

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A visual-omics foundation model to bridge histopathology image with transcriptomics.
Weiqing Chen, Pengzhi Zhang, Tu N Tran, Yiwei Xiao, Shengyu Li, Keith Youker

Res Sq· April 2025

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Thor: a platform for cell-level investigation of spatial transcriptomics and histology.
Pengzhi Zhang, Weiqing Chen, Tu Nhi Tran, Minghao Zhou, Kaylee N Carter, Keith Youker

Res Sq· March 2025

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Myocardial Recovery versus Myocardial Regeneration: Mechanisms and Therapeutic Modulation.
John P Cooke, Keith A Youker, Li Lai

Methodist Debakey Cardiovasc J· August 2024

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Mitochondrial Ca Uniporter-Dependent Energetic Dysfunction Drives Hypertrophy in Heart Failure.
Hugo Alves-Figueiredo, Christian Silva-Platas, Manuel Estrada, Yuriana Oropeza-Almazán, Martin Ramos-González, Keith Youker

JACC Basic Transl Sci· April 2024

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Future Impact of mRNA Therapy on Cardiovascular Diseases.
John P Cooke, Keith A Youker

Methodist Debakey Cardiovasc J· January 2023

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3'UTR shortening of profibrotic genes and reversibility of fibrosis in patients with end-stage right ventricular failure.
Rahul Neupane, Katarzyna A Cieslik, Keith Youker, Suresh Selvaraj Palaniyandi, Ashrith Guha

Clin Transl Med· September 2022

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An Platform to Study Reversible Endothelial-to-Mesenchymal Transition.
Muthu Kumar Krishnamoorthi, Rajarajan A Thandavarayan, Keith A Youker, Arvind Bhimaraj

Front Pharmacol· June 2022

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Cleavage stimulating factor 64 depletion mitigates cardiac fibrosis through alternative polyadenylation.
Rahul Neupane, Keith Youker, Hari Krishna Yalamanchili, Katarzyna A Cieslik, Harry Karmouty-Quintana

Biochem Biophys Res Commun· March 2022

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Long term development of diastolic dysfunction and heart failure with preserved left ventricular ejection fraction in heart transplant recipients.
Pimprapa Vejpongsa, Guillermo Torre-Amione, Hernan G Marcos-Abdala, Salil Kumar, Keith Youker

Sci Rep· March 2022

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STK35 Gene Therapy Attenuates Endothelial Dysfunction and Improves Cardiac Function in Diabetes.
Darukeshwara Joladarashi, Yanan Zhu, Matthew Willman, Kevin Nash, Maria Cimini, Keith A Youker

Front Cardiovasc Med· January 2022

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Platelet rich plasma concentration improves biologic mesh incorporation and decreases multinucleated giant cells in a dose dependent fashion.
Raquel Araujo-Gutierrez, Jeffrey L Van Eps, Jacob C Scherba, Albert Thomas Anastasio, Fernando Cabrera, Keith Youker

J Tissue Eng Regen Med· November 2021

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Endothelial Dysfunction-related Neurological Bleeds with Continuous Flow-Left Ventricular Assist Devices Measured by Digital Thermal Monitor.
Areeba Ali, Cesar Uribe, Raquel Araujo-Gutierrez, Ana S Cruz-Solbes, Hernan G Marcos-Abdala, Keith A Youker

ASAIO J· May 2021

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Role of Endothelial and Mesenchymal Cell Transitions in Heart Failure and Recovery Thereafter.
Guangyu Wang, Ana Sofia Cruz, Keith Youker, Hernan G Marcos-Abdala, Rajarajan A Thandavarayan

Front Genet· January 2021

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Mitochondrial Hyperacetylation in the Failing Hearts of Obese Patients Mediated Partly by a Reduction in SIRT3: The Involvement of the Mitochondrial Permeability Transition Pore.
Elena C Castillo, José A Morales, Héctor Chapoy-Villanueva, Christian Silva-Platas, Niria Treviño-Saldaña, Keith Youker

Cell Physiol Biochem· December 2019

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Erratum for Kirkpatrick et al., "Inducible Lung Epithelial Resistance Requires Multisource Reactive Oxygen Species Generation To Protect against Viral Infections".
Carson T Kirkpatrick, Yongxing Wang, Miguel M Leiva Juarez, Pooja Shivshankar, Jezreel Pantaleón García, Keith A Youker

mBio· April 2019

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Small molecule disruption of G protein βγ subunit signaling reprograms human macrophage phenotype and prevents autoimmune myocarditis in rats.
Vengadeshprabhu Karuppagounder, Anamika Bajpai, Shu Meng, Somasundaram Arumugam, Remya Sreedhar, Keith A Youker

PLoS One· January 2019

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Efficacy of sustained delivery of GC-1 from a Nanofluidic system in a spontaneously obese non-human primate: a case study.
Carly S Filgueira, Giacomo Bruno, Zachary W Smith, Corrine Ying Xuan Chua, Andrea Ballerini, Keith A Youker

Biomed Microdevices· June 2018

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Inducible Lung Epithelial Resistance Requires Multisource Reactive Oxygen Species Generation To Protect against Viral Infections.
Carson T Kirkpatrick, Yongxing Wang, Miguel M Leiva Juarez, Pooja Shivshankar, Jezreel Pantaleón García, Keith A Youker

mBio· May 2018

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Functionally redundant control of cardiac hypertrophic signaling by inositol 1,4,5-trisphosphate receptors.
M Iveth Garcia, Anja Karlstaedt, Jessica J Chen, Javier Amione-Guerra, Keith A Youker

J Mol Cell Cardiol· November 2017

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Inhibition of hyaluronan synthesis attenuates pulmonary hypertension associated with lung fibrosis.
Scott D Collum, Ning-Yuan Chen, Adriana M Hernandez, Ankit Hanmandlu, Heather Sweeney, Keith Youker

Br J Pharmacol· October 2017

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Epithelial to Mesenchymal Transition (EMT) and Endothelial to Mesenchymal Transition (EndMT): Role and Implications in Kidney Fibrosis.
Ana S Cruz-Solbes, Keith Youker

Results Probl Cell Differ· July 2017

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