Publications by authors named "Kelly Conlon"

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Targeting Ultrasmall Gold Nanoparticles with cRGD Peptide Increases the Uptake and Efficacy of Cytotoxic Payload.
Richard D Perrins, Lee-Anne McCarthy, Angela Robinson, Kelly L Spry, Valentin Cognet, Kelly Conlon

Nanomaterials (Basel)· November 2022

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Just in Time Teaching (JiTT) Infographics App for Teacher Development.
David Orner, Kelly Conlon, Melissa Affa, Alice Fornari

J Grad Med Educ· June 2022

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A highly potent maytansinoid analogue and its use as a cytotoxic therapeutic agent in gold nanoparticles for the treatment of hepatocellular carcinoma.
John Porter, Yao Ding, Sarah J M Hale, Richard D Perrins, Angela Robinson, Kelly Conlon

Bioorg Med Chem Lett· December 2020

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DM1 Loaded Ultrasmall Gold Nanoparticles Display Significant Efficacy and Improved Tolerability in Murine Models of Hepatocellular Carcinoma.
Sarah J M Hale, Richard D Perrins, Cristina Espinosa Garcı A, Alessandro Pace, Usoa Peral, Kelly Conlon

Bioconjug Chem· March 2019

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Nonclinical Cardiovascular Studies of Prucalopride, a Highly Selective 5-Hydroxytryptamine 4 Receptor Agonist.
Kelly Conlon, Joris H De Maeyer, Chris Bruce, Jan A J Schuurkes, Lee Christie

J Pharmacol Exp Ther· February 2018

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An Analysis of the Relationship Between Preclinical and Clinical QT Interval-Related Data.
Christopher E Pollard, Matthew Skinner, Stanley E Lazic, Helen M Prior, Kelly M Conlon

Toxicol Sci· September 2017

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Deferitazole, a new orally active iron chelator.
Robert C Hider, Xiaole Kong, Vincenzo Abbate, Rachel Harland, Kelly Conlon

Dalton Trans· March 2015

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Inhibition of TRPM8 channels reduces pain in the cold pressor test in humans.
Wendy J Winchester, Katrina Gore, Sophie Glatt, Wendy Petit, Jennifer C Gardiner, Kelly Conlon

J Pharmacol Exp Ther· November 2014

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Multiparameter optimization in CNS drug discovery: design of pyrimido[4,5-d]azepines as potent 5-hydroxytryptamine 2C (5-HT₂C) receptor agonists with exquisite functional selectivity over 5-HT₂A and 5-HT₂B receptors.
R Ian Storer, Paul E Brennan, Alan D Brown, Peter J Bungay, Kelly M Conlon

J Med Chem· June 2014

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Identification of 5-HT(2C) mediated mechanisms involved in urethral sphincter reflexes in a guinea-pig model of urethral function.
Kelly Conlon, Wes Miner, Scott McCleary, Gordon McMurray

BJU Int· July 2012

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Pyrimido[4,5-d]azepines as potent and selective 5-HT2C receptor agonists: design, synthesis, and evaluation of PF-3246799 as a treatment for urinary incontinence.
Mark D Andrews, Paul V Fish, Julian Blagg, Tiffini K Brabham, Paul E Brennan, Kelly M Conlon

Bioorg Med Chem Lett· May 2011

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Pharmacological properties of 2-((R-5-chloro-4-methoxymethylindan-1-yl)-1H-imidazole (PF-3774076), a novel and selective alpha1A-adrenergic partial agonist, in in vitro and in vivo models of urethral function.
Kelly Conlon, Clare Christy, Simon Westbrook, Gavin Whitlock, Lee Roberts

J Pharmacol Exp Ther· September 2009

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Discovery of a novel azepine series of potent and selective 5-HT2C agonists as potential treatments for urinary incontinence.
Paul E Brennan, Gavin A Whitlock, Danny K H Ho, Kelly Conlon, Gordon McMurray

Bioorg Med Chem Lett· September 2009

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Novel 2-imidazoles as potent, selective and CNS penetrant alpha1A adrenoceptor partial agonists.
Lee R Roberts, Justin Bryans, Kelly Conlon, Gordon McMurray, Alan Stobie

Bioorg Med Chem Lett· December 2008

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Novel 2-imidazoles as potent and selective alpha1A adrenoceptor partial agonists.
Gavin A Whitlock, Kelly Conlon, Gordon McMurray, Lee R Roberts, Alan Stobie

Bioorg Med Chem Lett· May 2008

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