Publications by authors named "Kelly D Pyles"

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Loss of mitochondrial pyruvate transport initiates cardiac glycogen accumulation and heart failure.
Rachel C Weiss, Kelly D Pyles, Kevin Cho, Michelle Brennan, Jonathan S Fisher

bioRxiv· April 2025

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Ketone Body Metabolism is Not Required for Improvement of Heart Failure by Ketogenic Diet in Mice.
Zachary Foulks, Carla J Weinheimer, Attila Kovacs, Jessica Michael, Kelly D Pyles

bioRxiv· September 2024

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Obesity-related T cell dysfunction impairs immunosurveillance and increases cancer risk.
Alexander Piening, Emily Ebert, Carter Gottlieb, Niloufar Khojandi, Lindsey M Kuehm, Kelly D Pyles

Nat Commun· April 2024

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Myeloperoxidase-derived hypochlorous acid targets human airway epithelial plasmalogens liberating protein modifying electrophilic 2-chlorofatty aldehydes.
Shubha Shakya, Kelly D Pyles, Carolyn J Albert, Rakesh P Patel, Kyle S McCommis

Redox Biol· February 2023

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Enhancing Hepatic MBOAT7 Expression in Mice With Nonalcoholic Steatohepatitis.
Martin C Sharpe, Kelly D Pyles, Taylor Hallcox, Dakota R Kamm, Michaela Piechowski

Gastro Hep Adv· February 2023

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Identification of Novel Mitochondrial Pyruvate Carrier Inhibitors by Homology Modeling and Pharmacophore-Based Virtual Screening.
Lamees Hegazy, Lauren E Gill, Kelly D Pyles, Christopher Kaiho, Sophia Kchouk

Biomedicines· February 2022

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Novel insulin sensitizer MSDC-0602K improves insulinemia and fatty liver disease in mice, alone and in combination with liraglutide.
Dakota R Kamm, Kelly D Pyles, Martin C Sharpe, Laura N Healy, Jerry R Colca

J Biol Chem· August 2021

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Fructose Promotes Cytoprotection in Melanoma Tumors and Resistance to Immunotherapy.
Lindsey M Kuehm, Niloufar Khojandi, Alexander Piening, Lauryn E Klevorn, Simone C Geraud, Kelly D Pyles

Cancer Immunol Res· February 2021

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Nutritional modulation of heart failure in mitochondrial pyruvate carrier-deficient mice.
Kyle S McCommis, Attila Kovacs, Carla J Weinheimer, Trevor M Shew, Timothy R Koves, Kelly D Pyles

Nat Metab· November 2020

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Nuclear export factor 3 regulates localization of small nucleolar RNAs.
Melissa W Li, Arthur C Sletten, Jiyeon Lee, Kelly D Pyles, Scot J Matkovich

J Biol Chem· December 2017

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Rpl13a small nucleolar RNAs regulate systemic glucose metabolism.
Jiyeon Lee, Alexis N Harris, Christopher L Holley, Jana Mahadevan, Kelly D Pyles

J Clin Invest· December 2016

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