Publications by authors named "Kelly Rausch"

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A Vaccine to Block Transmission.
Sara A Healy, Issaka Sagara, Mahamadoun H Assadou, Abdoulaye Katile, Mamady Kone, Kelly M Rausch

NEJM Evid· July 2025

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SARS-CoV-2 Receptor Binding Domain (RBD) Protein-Protein Conjugate Induces Similar or Better Antibody Responses as Spike mRNA in Rhesus Macaques.
Puthupparampil V Scaria, Christopher G Rowe, Ivan Kosik, Zhe Hu, Jonathan P Renn, Kelly M Rausch

Vaccines (Basel)· June 2025

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Safety and efficacy of PfSPZ Vaccine against malaria in healthy adults and women anticipating pregnancy in Mali: two randomised, double-blind, placebo-controlled, phase 1 and 2 trials.
Halimatou Diawara, Sara A Healy, Agnes Mwakingwe-Omari, Djibrilla Issiaka, Aye Diallo, Kelly M Rausch

Lancet Infect Dis· December 2024

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mRNA vaccines expressing malaria transmission-blocking antigens Pfs25 and Pfs230D1 induce a functional immune response.
Puthupparampil V Scaria, Nicole Roth, Kim Schwendt, Olga V Muratova, Nada Alani, Kelly M Rausch

NPJ Vaccines· January 2024

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Aotus nancymaae model predicts human immune response to the placental malaria vaccine candidate VAR2CSA.
Justin Doritchamou, Morten A Nielsen, Arnaud Chêne, Nicola K Viebig, Lynn E Lambert, Kelly M Rausch

Lab Anim (NY)· December 2023

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Malaria transmission-blocking vaccines Pfs230D1-EPA and Pfs25-EPA in Alhydrogel in healthy Malian adults; a phase 1, randomised, controlled trial.
Issaka Sagara, Sara A Healy, Mahamadoun H Assadou, Mamady Kone, Bruce J Swihart, Kelly M Rausch

Lancet Infect Dis· November 2023

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Preclinical evaluations of Pfs25-EPA and Pfs230D1-EPA in AS01 for a vaccine to reduce malaria transmission.
Kelly M Rausch, Emma K Barnafo, Lynn E Lambert, Olga Muratova, J Patrick Gorres

iScience· July 2023

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Structural and immunological differences in Plasmodium falciparum sexual stage transmission-blocking vaccines comprised of Pfs25-EPA nanoparticles.
Nicholas J MacDonald, Kavita Singh, Karine Reiter, Vu Nguyen, Richard Shimp, Kelly M Rausch

NPJ Vaccines· April 2023

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Protein-protein conjugation enhances the immunogenicity of SARS-CoV-2 receptor-binding domain (RBD) vaccines.
Puthupparampil V Scaria, Chris G Rowe, Beth B Chen, Thayne H Dickey, Jonathan P Renn, Kelly M Rausch

iScience· August 2022

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Safety and efficacy of a three-dose regimen of Plasmodium falciparum sporozoite vaccine in adults during an intense malaria transmission season in Mali: a randomised, controlled phase 1 trial.
Mahamadou S Sissoko, Sara A Healy, Abdoulaye Katile, Irfan Zaidi, Zonghui Hu, Kelly M Rausch

Lancet Infect Dis· March 2022

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Malaria transmission-blocking conjugate vaccine in ALFQ adjuvant induces durable functional immune responses in rhesus macaques.
Puthupparampil V Scaria, Charles Anderson, Olga Muratova, Nada Alani, Hung V Trinh, Kelly M Rausch

NPJ Vaccines· December 2021

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Pfs230 yields higher malaria transmission-blocking vaccine activity than Pfs25 in humans but not mice.
Sara A Healy, Charles Anderson, Bruce J Swihart, Agnes Mwakingwe, Erin E Gabriel, Kelly M Rausch

J Clin Invest· April 2021

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Comparison of carrier proteins to conjugate malaria transmission blocking vaccine antigens, Pfs25 and Pfs230.
Puthupparampil V Scaria, Beth B Chen, Christopher G Rowe, Nada Alani, Olga V Muratova, Kelly M Rausch

Vaccine· July 2020

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Safety and immunogenicity of Pfs25H-EPA/Alhydrogel, a transmission-blocking vaccine against Plasmodium falciparum: a randomised, double-blind, comparator-controlled, dose-escalation study in healthy Malian adults.
Issaka Sagara, Sara A Healy, Mahamadoun H Assadou, Erin E Gabriel, Mamady Kone, Kelly M Rausch

Lancet Infect Dis· September 2018

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TLR-adjuvanted nanoparticle vaccines differentially influence the quality and longevity of responses to malaria antigen Pfs25.
Elizabeth A Thompson, Sebastian Ols, Kazutoyo Miura, Kelly Rausch, David L Narum

JCI Insight· May 2018

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Protein-protein conjugate nanoparticles for malaria antigen delivery and enhanced immunogenicity.
Puthupparampil V Scaria, Beth Chen, Christopher G Rowe, David S Jones, Emma Barnafo, Kelly M Rausch

PLoS One· February 2018

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Determination of Protein Content in Alhydrogel-Based Vaccines by O-Phthalaldehyde Assay.
Kelly M Rausch, Daming Zhu

Methods Mol Biol· January 2018

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Identification of Protective B-Cell Epitopes within the Novel Malaria Vaccine Candidate Plasmodium falciparum Schizont Egress Antigen 1.
Christina E Nixon, Sangshin Park, Sunthorn Pond-Tor, Dipak Raj, Lynn E Lambert, Kelly M Rausch

Clin Vaccine Immunol· July 2017

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Safety and Immunogenicity of Pfs25-EPA/Alhydrogel®, a Transmission Blocking Vaccine against Plasmodium falciparum: An Open Label Study in Malaria Naïve Adults.
Kawsar R Talaat, Ruth D Ellis, Janet Hurd, Autumn Hentrich, Erin Gabriel, Kelly M Rausch

PLoS One· May 2017

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Accelerated and long term stability study of Pfs25-EPA conjugates adjuvanted with Alhydrogel®.
Daming Zhu, Yimin Wu, Holly McClellan, Weili Dai, Kelly Rausch

Vaccine· May 2017

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Accounting for adjuvant-induced artifacts in the characterization of vaccine formulations by polyacrylamide gel electrophoresis.
Virginie Jakob, Livia Brunner, Christophe Barnier-Quer, Molly Blust, Nicolas Collin, Kelly M Rausch

Ther Adv Vaccines· April 2017

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Adjuvant and carrier protein-dependent T-cell priming promotes a robust antibody response against the Plasmodium falciparum Pfs25 vaccine candidate.
Andrea J Radtke, Charles F Anderson, Nicolas Riteau, Kelly Rausch, Puthupparampil Scaria

Sci Rep· January 2017

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Structural and Immunological Characterization of Recombinant 6-Cysteine Domains of the Plasmodium falciparum Sexual Stage Protein Pfs230.
Nicholas J MacDonald, Vu Nguyen, Richard Shimp, Karine Reiter, Raul Herrera, Kelly Rausch

J Biol Chem· September 2016

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A Method for Producing Protein Nanoparticles with Applications in Vaccines.
David S Jones, Christopher G Rowe, Beth Chen, Karine Reiter, Kelly M Rausch

PLoS One· July 2016

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Reversible Conformational Change in the Plasmodium falciparum Circumsporozoite Protein Masks Its Adhesion Domains.
Raul Herrera, Charles Anderson, Krishan Kumar, Alvaro Molina-Cruz, Vu Nguyen, Kelly M Rausch

Infect Immun· October 2015

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