Publications by authors named "Kelly Teske"

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Interrogating direct NLRP3 engagement and functional inflammasome inhibition using cellular assays.
Kelly A Teske, Cesear Corona, Jennifer Wilkinson, Daniel Mamott, David A Good

Cell Chem Biol· February 2024

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DELs enable the development of BRET probes for target engagement studies in cells.
Kelly A Teske, Wenji Su, Cesear R Corona, Jing Wen, Jason Deng

Cell Chem Biol· August 2023

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Biological evaluation and synthesis of calcitroic acid.
Olivia B Yu, Daniel A Webb, Elliot S Di Milo, Tania R Mutchie, Kelly A Teske

Bioorg Chem· November 2021

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A review of currently identified small molecule modulators of microRNA function.
Emile N Van Meter, Jackline A Onyango, Kelly A Teske

Eur J Med Chem· February 2020

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Inhibition of hedgehog signaling by stereochemically defined des-triazole itraconazole analogues.
Jiachen Wen, Kelly A Teske, M Kyle Hadden

Bioorg Med Chem Lett· January 2020

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Probing the Ligand-Binding Pocket of BTN3A1.
Michael M Poe, Sherry S Agabiti, Caroline Liu, Victoria Li, Kelly A Teske

J Med Chem· July 2019

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Structure-Activity Relationships for Itraconazole-Based Triazolone Analogues as Hedgehog Pathway Inhibitors.
Jennifer R Pace, Kelly A Teske, Lianne Q Chau, Radha Charan Dash, Angela M Zaino

J Med Chem· April 2019

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Development of posaconazole-based analogues as hedgehog signaling pathway inhibitors.
Kelly A Teske, Radha Charan Dash, Shana R Morel, Lianne Q Chau, Robert J Wechsler-Reya

Eur J Med Chem· February 2019

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Novel VDR antagonists based on the GW0742 scaffold.
Kelly A Teske, Jonathan W Bogart, Leggy A Arnold

Bioorg Med Chem Lett· February 2018

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Parallel Chemistry Approach to Identify Novel Nuclear Receptor Ligands Based on the GW0742 Scaffold.
Kelly A Teske, Ganesha Rai, Premchendar Nandhikonda, Preetpal S Sidhu, Belaynesh Feleke

ACS Comb Sci· October 2017

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Methyllysine binding domains: Structural insight and small molecule probe development.
Kelly A Teske, M Kyle Hadden

Eur J Med Chem· August 2017

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Hydrogen peroxide activated quinone methide precursors with enhanced DNA cross-linking capability and cytotoxicity towards cancer cells.
Yibin Wang, Heli Fan, Kumudha Balakrishnan, Zechao Lin, Sheng Cao, Kelly A Teske

Eur J Med Chem· June 2017

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Inhibitors for the Vitamin D Receptor-Coregulator Interaction.
Kelly A Teske, Olivia Yu, Leggy A Arnold

Vitam Horm· January 2017

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Synthesis and Characterization of a Novel γ-Aminobutyric Acid Type A (GABA) Receptor Ligand That Combines Outstanding Metabolic Stability, Pharmacokinetics, and Anxiolytic Efficacy.
Michael M Poe, Kashi Reddy Methuku, Guanguan Li, Ashwini R Verma, Kelly A Teske

J Med Chem· December 2016

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Synthesis and evaluation of vitamin D receptor-mediated activities of cholesterol and vitamin D metabolites.
Kelly A Teske, Jonathon W Bogart, Luis M Sanchez, Olivia B Yu, Joshua V Preston

Eur J Med Chem· February 2016

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Antitumor Activity of 3-Indolylmethanamines 31B and PS121912.
Margaret L Guthrie, Preetpal S Sidhu, Emily K Hill, Timothy C Horan, Premchendar Nandhikonda, Kelly A Teske

Anticancer Res· November 2015

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Anticancer activity of VDR-coregulator inhibitor PS121912.
Preetpal S Sidhu, Kelly Teske, Belaynesh Feleke, Nina Y Yuan, Margaret L Guthrie

Cancer Chemother Pharmacol· October 2014

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Development of novel Vitamin D Receptor-Coactivator Inhibitors.
Preetpal S Sidhu, Nicholas Nassif, Megan M McCallum, Kelly Teske, Belaynesh Feleke

ACS Med Chem Lett· February 2014

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IDENTIFICATION OF VDR ANTAGONISTS AMONG NUCLEAR RECEPTOR LIGANDS USING VIRTUAL SCREENING.
Kelly Teske, Premchendar Nandhikonda, Jonathan W Bogart, Belaynesh Feleke, Preetpal Sidhu

Nucl Receptor Res· January 2014

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Modulation of Transcription mediated by the Vitamin D Receptor and the Peroxisome Proliferator-Activated Receptor δ in the presence of GW0742 analogs.
Kelly Teske, Premchendar Nandhikonda, Jonathan W Bogart, Belaynesh Feleke, Preetpal Sidhu

J Biomol Res Ther· January 2014

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Peroxisome proliferation-activated receptor δ agonist GW0742 interacts weakly with multiple nuclear receptors, including the vitamin D receptor.
Premchendar Nandhikonda, Adam Yasgar, Athena M Baranowski, Preetpal S Sidhu, Megan M McCallum, Kelly Teske

Biochemistry· June 2013

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