Publications by authors named "Ken Asada"

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SEgene identifies links between super enhancers and gene expression across cell types.
Norio Shinkai, Ken Asada, Hidenori Machino, Ken Takasawa, Satoshi Takahashi

NPJ Syst Biol Appl· May 2025

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Rare genetic variants involved in increased risk of paroxysmal atrial fibrillation in a Japanese population.
Kanji Tabata, Takeaki Sudo, Yuki Nagata, Kensuke Ihara, Ken Asada

Sci Rep· April 2025

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BET inhibitor JQ1 induces apoptosis of ovarian and endometrial endometrioid carcinoma cells by downregulating .
Saki Tanimoto, Kenbun Sone, Yuri Jonouchi, Ryuta Hachijo, Eri Suzuki, Ken Asada

Oncol Lett· March 2025

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Current status and future direction of cancer research using artificial intelligence for clinical application.
Ryuji Hamamoto, Masaaki Komatsu, Masayoshi Yamada, Kazuma Kobayashi, Masamichi Takahashi, Ken Asada

Cancer Sci· February 2025

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Automated Assessment of the Pulmonary Artery-to-Ascending Aorta Ratio in Fetal Cardiac Ultrasound Screening Using Artificial Intelligence.
Rina Aoyama, Masaaki Komatsu, Naoaki Harada, Reina Komatsu, Akira Sakai, Ken Asada

Bioengineering (Basel)· December 2024

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Multi-omics and clustering analyses reveal the mechanisms underlying unmet needs for patients with lung adenocarcinoma and identify potential therapeutic targets.
Ken Asada, Syuzo Kaneko, Ken Takasawa, Kouya Shiraishi, Norio Shinkai

Mol Cancer· September 2024

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Comparison of Vision Transformers and Convolutional Neural Networks in Medical Image Analysis: A Systematic Review.
Satoshi Takahashi, Yusuke Sakaguchi, Nobuji Kouno, Ken Takasawa, Kenichi Ishizu, Ken Asada

J Med Syst· September 2024

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Mechanism of ERBB2 gene overexpression by the formation of super-enhancer with genomic structural abnormalities in lung adenocarcinoma without clinically actionable genetic alterations.
Syuzo Kaneko, Ken Takasawa, Ken Asada, Kouya Shiraishi, Noriko Ikawa

Mol Cancer· June 2024

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Edge AI Model Deployed for Real-Time Detection of Atrial Fibrillation Risk during Sinus Rhythm.
Hongmin Wu, Takumi Sawada, Takafumi Goto, Tatsuya Yoneyama, Tetsuo Sasano, Ken Asada

J Clin Med· April 2024

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Advances in cancer DNA methylation analysis with methPLIER: use of non-negative matrix factorization and knowledge-based constraints to enhance biological interpretability.
Ken Takasawa, Ken Asada, Syuzo Kaneko, Kouya Shiraishi, Hidenori Machino

Exp Mol Med· March 2024

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Integrative analysis reveals early epigenetic alterations in high-grade serous ovarian carcinomas.
Hidenori Machino, Ai Dozen, Mariko Konaka, Masaaki Komatsu, Kohei Nakamura, Ken Asada

Exp Mol Med· October 2023

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Analysis of super-enhancer using machine learning and its application to medical biology.
Ryuji Hamamoto, Ken Takasawa, Norio Shinkai, Hidenori Machino, Nobuji Kouno, Ken Asada

Brief Bioinform· May 2023

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Tumor Suppressive Role of the Gene in Ovarian Clear Cell Carcinoma.
Ai Dozen, Kanto Shozu, Norio Shinkai, Noriko Ikawa, Rina Aoyama, Ken Asada

J Pers Med· December 2022

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Repression of the PRELP gene is relieved by histone deacetylase inhibitors through acetylation of histone H2B lysine 5 in bladder cancer.
Kanto Shozu, Syuzo Kaneko, Norio Shinkai, Ai Dozen, Hirofumi Kosuge, Ken Asada

Clin Epigenetics· November 2022

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Regulates Cell-Cell Adhesion and EMT and Inhibits Retinoblastoma Progression.
Jack Hopkins, Ken Asada, Alex Leung, Vasiliki Papadaki, Hongorzul Davaapil

Cancers (Basel)· October 2022

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Introducing AI to the molecular tumor board: one direction toward the establishment of precision medicine using large-scale cancer clinical and biological information.
Ryuji Hamamoto, Takafumi Koyama, Nobuji Kouno, Tomohiro Yasuda, Shuntaro Yui, Ken Asada

Exp Hematol Oncol· October 2022

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Application of non-negative matrix factorization in oncology: one approach for establishing precision medicine.
Ryuji Hamamoto, Ken Takasawa, Hidenori Machino, Kazuma Kobayashi, Satoshi Takahashi, Ken Asada

Brief Bioinform· July 2022

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Systemic DNA/RNA heteroduplex oligonucleotide administration for regulating the gene expression of dorsal root ganglion and sciatic nerve.
Hidetoshi Kaburagi, Tetsuya Nagata, Mitsuhiro Enomoto, Takashi Hirai, Masaki Ohyagi, Ken Asada

Mol Ther Nucleic Acids· June 2022

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Automated Endocardial Border Detection and Left Ventricular Functional Assessment in Echocardiography Using Deep Learning.
Shunzaburo Ono, Masaaki Komatsu, Akira Sakai, Hideki Arima, Mie Ochida, Ken Asada

Biomedicines· May 2022

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Medical Professional Enhancement Using Explainable Artificial Intelligence in Fetal Cardiac Ultrasound Screening.
Akira Sakai, Masaaki Komatsu, Reina Komatsu, Ryu Matsuoka, Suguru Yasutomi, Ken Asada

Biomedicines· February 2022

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Downregulation of METTL6 mitigates cell progression, migration, invasion and adhesion in hepatocellular carcinoma by inhibiting cell adhesion molecules.
Amina Bolatkan, Ken Asada, Syuzo Kaneko, Kruthi Suvarna, Noriko Ikawa

Int J Oncol· January 2022

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The metabolic stress-activated checkpoint LKB1-MARK3 axis acts as a tumor suppressor in high-grade serous ovarian carcinoma.
Hidenori Machino, Syuzo Kaneko, Masaaki Komatsu, Noriko Ikawa, Ken Asada

Commun Biol· January 2022

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Single-Cell Analysis Using Machine Learning Techniques and Its Application to Medical Research.
Ken Asada, Ken Takasawa, Hidenori Machino, Satoshi Takahashi, Norio Shinkai

Biomedicines· October 2021

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Epigenetic Mechanisms Underlying COVID-19 Pathogenesis.
Syuzo Kaneko, Ken Takasawa, Ken Asada, Norio Shinkai, Amina Bolatkan

Biomedicines· September 2021

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Application of Artificial Intelligence in COVID-19 Diagnosis and Therapeutics.
Ken Asada, Masaaki Komatsu, Ryo Shimoyama, Ken Takasawa, Norio Shinkai

J Pers Med· September 2021

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