Publications by authors named "Ken Olaussen"

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Multimodal CustOmics: A unified and interpretable multi-task deep learning framework for multimodal integrative data analysis in oncology.
Hakim Benkirane, Maria Vakalopoulou, David Planchard, Julien Adam, Ken Olaussen

PLoS Comput Biol· June 2025

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Understanding and Overcoming Resistance to Selective FGFR Inhibitors across FGFR2-Driven Malignancies.
Francesco Facchinetti, Yohann Loriot, Floriane Brayé, Damien Vasseur, Rastislav Bahleda, Ken A Olaussen

Clin Cancer Res· November 2024

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Deciphering resistance mechanisms in cancer: final report of MATCH-R study with a focus on molecular drivers and PDX development.
Damien Vasseur, Ludovic Bigot, Kristi Beshiri, Juan Flórez-Arango, Francesco Facchinetti, Ken André Olaussen

Mol Cancer· October 2024

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Resistance to Selective FGFR Inhibitors in FGFR-Driven Urothelial Cancer.
Francesco Facchinetti, Antoine Hollebecque, Floriane Braye, Damien Vasseur, Yoann Pradat, Ken A Olaussen

Cancer Discov· September 2023

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Association of Molecular Profiles and Mutational Status With Distinct Histological Lung Adenocarcinoma Subtypes. An Analysis of the LACE-Bio Data.
Prashanth Ashok Kumar, Maryam Karimi, Alina Basnet, Lesley Seymour, Robert Kratzke, Ken André Olaussen

Clin Lung Cancer· September 2023

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Feasibility and first reports of the MATCH-R repeated biopsy trial at Gustave Roussy.
Gonzalo Recondo, Linda Mahjoubi, Aline Maillard, Yohann Loriot, Ludovic Bigot, Ken A Olaussen

NPJ Precis Oncol· September 2020

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Molecular mechanisms of resistance to BRAF and MEK inhibitors in BRAF non-small cell lung cancer.
Francesco Facchinetti, Ludovic Lacroix, Laura Mezquita, Jean-Yves Scoazec, Yohann Loriot, Ken A Olaussen

Eur J Cancer· June 2020

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Facts and New Hopes on Selective FGFR Inhibitors in Solid Tumors.
Francesco Facchinetti, Antoine Hollebecque, Rastislav Bahleda, Yohann Loriot, Ken A Olaussen

Clin Cancer Res· February 2020

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Diverse Resistance Mechanisms to the Third-Generation ALK Inhibitor Lorlatinib in ALK-Rearranged Lung Cancer.
Gonzalo Recondo, Laura Mezquita, Francesco Facchinetti, David Planchard, Anas Gazzah, Ken A Olaussen

Clin Cancer Res· January 2020

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The "Guardian of the Genome"-An Old Key to Unlock the ERCC1 Issue.
Luc Friboulet, Jean-Charles Soria, Ken André Olaussen

Clin Cancer Res· April 2019

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Making the first move in EGFR-driven or ALK-driven NSCLC: first-generation or next-generation TKI?
Gonzalo Recondo, Francesco Facchinetti, Ken A Olaussen, Benjamin Besse, Luc Friboulet

Nat Rev Clin Oncol· November 2018

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Tumor Mutation Burden as a Biomarker in Resected Non-Small-Cell Lung Cancer.
Siddhartha Devarakonda, Federico Rotolo, Ming-Sound Tsao, Irena Lanc, Elisabeth Brambilla, Ken A Olaussen

J Clin Oncol· October 2018

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Genome-wide copy number analyses of samples from LACE-Bio project identify novel prognostic and predictive markers in early stage non-small cell lung cancer.
Federico Rotolo, Chang-Qi Zhu, Elisabeth Brambilla, Stephen L Graziano, Ken Olaussen

Transl Lung Cancer Res· June 2018

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DNA repair deficiency sensitizes lung cancer cells to NAD+ biosynthesis blockade.
Mehdi Touat, Tony Sourisseau, Nicolas Dorvault, Roman M Chabanon, Marlène Garrido, Ken A Olaussen

J Clin Invest· April 2018

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A novel antibody-based approach to detect the functional ERCC1-202 isoform.
Mei-Shiue Kuo, Julien Adam, Nicolas Dorvault, Angélique Robin, Luc Friboulet, Ken A Olaussen

DNA Repair (Amst)· April 2018

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TPF induction chemotherapy increases PD-L1 expression in tumour cells and immune cells in head and neck squamous cell carcinoma.
Charlotte Leduc, Julien Adam, Emilie Louvet, Tony Sourisseau, Nicolas Dorvault, Ken A Olaussen

ESMO Open· January 2018

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Translational regulation of the mRNA encoding the ubiquitin peptidase USP1 involved in the DNA damage response as a determinant of Cisplatin resistance.
Tony Sourisseau, Carole Helissey, Céline Lefebvre, Florence Ponsonnailles, Hélène Malka-Mahieu, Ken A Olaussen

Cell Cycle· October 2016

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MMS19 as a potential predictive marker of adjuvant chemotherapy benefit in resected non-small cell lung cancer.
Julien Adam, Tony Sourisseau, Ken A Olaussen, Angélique Robin, Chang Q Zhu

Cancer Biomark· September 2016

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Osteopontin and thrombospondin-1 play opposite roles in promoting tumor aggressiveness of primary resected non-small cell lung cancer.
Mathieu Rouanne, Julien Adam, Aïcha Goubar, Angélique Robin, Caroline Ohana, Ken André Olaussen

BMC Cancer· July 2016

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No evidence for viral sequences in five lepidic adenocarcinomas (former "BAC") by a high-throughput sequencing approach.
Nicolas Berthet, Lionel Frangeul, Ken André Olaussen, Elisabeth Brambilla, Nicolas Dorvault

BMC Res Notes· December 2015

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PARP inhibitors: an interesting pathway also for non-small cell lung cancer?
Matteo Giaj Levra, Ken Andre Olaussen, Silvia Novello, Jean-Charles Soria

Curr Pharm Des· March 2015

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ERCC1 function in nuclear excision and interstrand crosslink repair pathways is mediated exclusively by the ERCC1-202 isoform.
Luc Friboulet, Sophie Postel-Vinay, Tony Sourisseau, Julien Adam, Annabelle Stoclin, Ken André Olaussen

Cell Cycle· October 2013

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19q13-ERCC1 gene copy number increase in non--small-cell lung cancer.
Elsa Vanhecke, Alexander Valent, Ximing Tang, Philippe Vielh, Luc Friboulet, Ken A Olaussen

Clin Lung Cancer· September 2013

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Cisplatin resistance associated with PARP hyperactivation.
Judith Michels, Ilio Vitale, Lorenzo Galluzzi, Julien Adam, Ken André Olaussen

Cancer Res· April 2013

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ERCC1 isoform expression and DNA repair in non-small-cell lung cancer.
Luc Friboulet, Ken André Olaussen, Jean-Pierre Pignon, Frances A Shepherd, Ming-Sound Tsao

N Engl J Med· March 2013

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