Publications by authors named "Ken Tajima"

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Challenges in the Development of Novel Therapies for Thoracic Malignancies.
Ken Tajima

Juntendo Med J· November 2025

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Novel Approach to Overcome Osimertinib Resistance Using Bromodomain and Extra-Terminal Domain Inhibitors.
Yosuke Miyashita, Ken Tajima, Kenta Izumi, Naohisa Matsumoto, Daisuke Hayakawa

Cancer Sci· May 2025

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Second malignancy in advanced or recurrent non-small cell lung cancer after the advent of molecular targeted drugs and immunotherapy.
Yoshihiro Masui, Takehito Shukuya, Shunichi Kataoka, Hitomi Shiozaki, Kana Kurokawa, Ken Tajima

Thorac Cancer· November 2024

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Anti-Müllerian hormone type II receptor protein expression in non-small cell lung cancer and the effect of AMH/AMHR2 signaling on cancer cell proliferation.
Yoshika Koinuma, Yoichiro Mitsuishi, Wira Winardi, Moulid Hidayat, Aditya Wirawan, Ken Tajima

Thorac Cancer· October 2024

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Clinical potential of SKP2 as diagnostic marker and therapeutic target in small cell lung cancer.
Naohisa Matsumoto, Ken Tajima, Fumiyuki Takahashi, Yoichiro Mitsuishi, Aditya Wirawan

Respir Investig· September 2024

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Trophoblast Cell Surface Antigen 2 Expression in Thymic Carcinoma: Brief Report.
Kana Kurokawa, Tetsuhiko Asao, Takuo Hayashi, Satsuki Kishikawa, Koichiro Kanamori, Ken Tajima

JTO Clin Res Rep· July 2024

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Comparison of ASCL1, NEUROD1, and POU2F3 expression in surgically resected specimens, paired tissue microarrays, and lymph node metastases in small cell lung carcinoma.
Takafumi Handa, Takuo Hayashi, Ayako Ura, Isamu Watanabe, Kazuya Takamochi, Ken Tajima

Histopathology· May 2023

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CALML5 is a novel diagnostic marker for differentiating thymic squamous cell carcinoma from type B3 thymoma.
Koichiro Kanamori, Kentaro Suina, Takehito Shukuya, Fumiyuki Takahashi, Takuo Hayashi, Ken Tajima

Thorac Cancer· April 2023

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Early Detection of Therapeutic Benefit from PD-1/PD-L1 Blockade in Advanced Lung Cancer by Monitoring Cachexia-Related Circulating Cytokines.
Shiting Xu, Keita Miura, Takehito Shukuya, Sonoko Harada, Masahiro Fujioka, Ken Tajima

Cancers (Basel)· February 2023

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Successful restart of chemotherapy in a patient with primary mediastinal nonseminomatous germ cell tumor after COVID-19 infection.
Yuki Tanabe, Takehito Shukuya, Yuichi Nagata, Takayasu Watanabe, Koichi Seto, Ken Tajima

Thorac Cancer· September 2022

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Survival past five years with advanced, EGFR-mutated or ALK-rearranged non-small cell lung cancer-is there a "tail plateau" in the survival curve of these patients?
Shoko Sonobe Shimamura, Takehito Shukuya, Tetsuhiko Asao, Daisuke Hayakawa, Kana Kurokawa, Ken Tajima

BMC Cancer· March 2022

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A Novel Therapeutic Strategy Targeting the Mesenchymal Phenotype of Malignant Pleural Mesothelioma by Suppressing LSD1.
Aditya Wirawan, Ken Tajima, Fumiyuki Takahashi, Yoichiro Mitsuishi, Wira Winardi

Mol Cancer Res· January 2022

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SCLC-J1, a novel small cell lung cancer cell line.
Kazuo Ohara, Shintaro Kinoshita, Jun Ando, Yoko Azusawa, Midori Ishii, Ken Tajima

Biochem Biophys Rep· September 2021

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Tranilast Inhibits Pulmonary Fibrosis by Suppressing TGFβ/SMAD2 Pathway.
Motoyasu Kato, Fumiyuki Takahashi, Tadashi Sato, Yoichiro Mitsuishi, Ken Tajima

Drug Des Devel Ther· August 2021

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Zinc-finger E-box-binding homeobox 1 (ZEB1) plays a crucial role in the maintenance of lung cancer stem cells resistant to gefitinib.
Fariz Nurwidya, Fumiyuki Takahashi, Wira Winardi, Ken Tajima, Yoichiro Mitsuishi

Thorac Cancer· May 2021

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Nintedanib inhibits epithelial-mesenchymal transition in A549 alveolar epithelial cells through regulation of the TGF-β/Smad pathway.
Hiroaki Ihara, Yoichiro Mitsuishi, Motoyasu Kato, Fumiyuki Takahashi, Ken Tajima

Respir Investig· July 2020

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Activation of insulin-like growth factor-1 receptor confers acquired resistance to osimertinib in non-small cell lung cancer with EGFR T790M mutation.
Daisuke Hayakawa, Fumiyuki Takahashi, Yoichiro Mitsuishi, Ken Tajima, Moulid Hidayat

Thorac Cancer· January 2020

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Role of FBXW7 in the quiescence of gefitinib-resistant lung cancer stem cells in EGFR-mutant non-small cell lung cancer.
Moulid Hidayat, Yoichiro Mitsuishi, Fumiyuki Takahashi, Ken Tajima, Toshifumi Yae

Bosn J Basic Med Sci· November 2019

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23-valent pneumococcal polysaccharide vaccine improves survival in dialysis patients by preventing cardiac events.
Hiroaki Ihara, Kan Kikuchi, Hiromi Taniguchi, Shogo Fujita, Yuki Tsuruta, Ken Tajima

Vaccine· October 2019

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SETD1A protects from senescence through regulation of the mitotic gene expression program.
Ken Tajima, Satoru Matsuda, Toshifumi Yae, Benjamin J Drapkin, Robert Morris

Nat Commun· June 2019

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Dasatinib Suppresses TGFβ-Mediated Epithelial-Mesenchymal Transition in Alveolar Epithelial Cells and Inhibits Pulmonary Fibrosis.
Ryota Kanemaru, Fumiyuki Takahashi, Motoyasu Kato, Yoichiro Mitsuishi, Ken Tajima

Lung· October 2018

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Surfactant protein-D predicts prognosis of interstitial lung disease induced by anticancer agents in advanced lung cancer: a case control study.
Kota Nakamura, Motoyasu Kato, Takehito Shukuya, Keita Mori, Yasuhito Sekimoto, Ken Tajima

BMC Cancer· May 2017

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LSD1/KDM1 isoform LSD1+8a contributes to neural differentiation in small cell lung cancer.
Takanobu Jotatsu, Shigehiro Yagishita, Ken Tajima, Fumiyuki Takahashi, Kaoru Mogushi

Biochem Biophys Rep· March 2017

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Genomic Instability Is Induced by Persistent Proliferation of Cells Undergoing Epithelial-to-Mesenchymal Transition.
Valentine Comaills, Lilian Kabeche, Robert Morris, Rémi Buisson, Min Yu, Ken Tajima

Cell Rep· December 2016

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Autofluorescence imaging bronchoscopy as a novel approach to the management of tracheobronchopathia osteochondroplastica: a case report.
Hiroaki Ihara, Ken Tajima, Hitomi Yoshikawa, Manabu Tajima, Norihiro Harada

J Thorac Dis· October 2016

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