Publications by authors named "Kenneth A Gruber"

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Melanocortin-4 receptor antagonist TCMCB07 alleviates chemotherapy-induced anorexia and weight loss in rats.
Xinxia Zhu, Russell Potterfield, Kenneth A Gruber, Emma Zhang, Samuel D Newton

J Clin Invest· November 2024

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Safety of TCMCB07, a melanocortin-4 antagonist peptide, in dogs with naturally occurring cachexia.
Sandra M Axiak-Bechtel, Stacey B Leach, Jessica R Newton-Northup, Rowan J Milner, Stacey A Fox-Alvarez, Kenneth A Gruber

J Vet Intern Med· November 2023

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Development of a Therapeutic Peptide for Cachexia Suggests a Platform Approach for Drug-like Peptides.
Kenneth A Gruber, Ren-Lai Ji, Fabio Gallazzi, Shaokai Jiang, Steven R Van Doren

ACS Pharmacol Transl Sci· May 2022

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Pharmacokinetics and safety of TCMCB07, a melanocortin-4 antagonist peptide in dogs.
Sandra M Axiak-Bechtel, Stacey B Leach, David G Scholten, Jessica R Newton-Northup, Brendan J Johnson, Kenneth A Gruber

Pharmacol Res Perspect· May 2021

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Characterization of the cellular transport mechanisms for the anti-cachexia candidate compound TCMCB07.
Yongjun Hu, Kenneth A Gruber, David E Smith

J Cachexia Sarcopenia Muscle· December 2020

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Melanocortin-4 receptor antagonist TCMCB07 ameliorates cancer- and chronic kidney disease-associated cachexia.
Xinxia Zhu, Michael F Callahan, Kenneth A Gruber, Marek Szumowski, Daniel L Marks

J Clin Invest· September 2020

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Neuropeptide Y and gamma-melanocyte stimulating hormone (gamma-MSH) share a common pressor mechanism of action.
Kenneth A Gruber, Wei Fan, Helena Akerberg, Dan Larhammar, Melissa J S Chee

Endocrine· June 2009

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