Publications by authors named "Kenneth D Westover"

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SRC at the crossroads of KRAS inhibitor resistance: Mechanisms and therapeutic opportunities.
Hui Tian, Dan Zhao, Zhuan Zhou, Alex Kim, Huocong Huang, Kenneth D Westover

Cancer Lett· December 2025

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Global Longitudinal Strain: A Potential Noninvasive Tool for Early Detection of Radiation-Induced Cardiac Dysfunction in Patients With Lung Cancer Receiving Thoracic Radiation Therapy.
Steven K Montalvo, Brian Lue, Eugenia Kakadiaris, Chul Ahn, Elizabeth Zhang-Velten, Kenneth D Westover

Int J Radiat Oncol Biol Phys· September 2025

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Osimertinib plus consolidative radiotherapy for advanced mutant non-small cell lung cancer: a multicentre, single-arm, phase 2 trial.
Sagus Sampath, Sawsan Rashdan, Puneeth Iyengar, Townes A Mickel, Song Zhang, Kenneth D Westover

EClinicalMedicine· September 2025

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A Computational Workflow for Structure-Guided Design of Potent and Selective Kinase Peptide Substrates.
Abeeb A Yekeen, Cynthia J Meyer, Melissa McCoy, Bruce Posner, Kenneth D Westover

bioRxiv· July 2025

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Concurrent and Consolidative Carboplatin Plus Nab-Paclitaxel or Paclitaxel in Locally Advanced NSCLC: A Multicenter, Randomized Clinical Trial.
Yuanyuan Zhang, Aaron M Laine, Puneeth Iyengar, Kenneth D Westover, Jonathan E Dowell

Int J Radiat Oncol Biol Phys· June 2025

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Beyond First-Generation KRAS Inhibitors: BBO-8520 Tests the Dual Mechanism Hypothesis.
Zhiwei Zhou, Kenneth D Westover

Cancer Discov· March 2025

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Oncogenic mutant KRAS inhibition through oxidation at cysteine 118.
Maximilian Kramer-Drauberg, Ettore Petrini, Alessia Mira, Enrico Patrucco, Rossella Scardaci, Kenneth D Westover

Mol Oncol· February 2025

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Concerning Safety and Efficacy of Concurrent and Consolidative Durvalumab With Thoracic Radiation Therapy in PDL1-Unselected Stage III Non-Small Cell Lung Cancer: Brief Report.
Yuanyuan Zhang, Puneeth Iyengar, Steven Montalvo, Kenneth D Westover, Sawsan Rashdan

Int J Radiat Oncol Biol Phys· January 2025

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Advances and Challenges in RAS Signaling Targeted Therapy in Leukemia.
Yu Chen, Zhenghao Yin, Kenneth D Westover, Zhiwei Zhou, Liping Shu

Mol Cancer Ther· January 2025

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SRC kinase drives multidrug resistance induced by KRAS-G12C inhibition.
Xinxin Song, Zhuan Zhou, Ammar Elmezayen, Runliu Wu, Chunhua Yu, Kenneth D Westover

Sci Adv· December 2024

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Experimental variables determine the outcome of RAS-RAS interactions.
Zhiwei Zhou, Tra Ly Nguyen, Xingxiao Li, Christel Poujol, Ewa Berlinska, Kenneth D Westover

J Biol Chem· November 2024

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GLUT3 promotes macrophage signaling and function via RAS-mediated endocytosis in atopic dermatitis and wound healing.
Dong-Min Yu, Jiawei Zhao, Eunice E Lee, Dohun Kim, Ruchika Mahapatra, Kenneth D Westover

J Clin Invest· November 2023

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Dynamic ultrasound molecular-targeted imaging of senescence in evaluation of lapatinib resistance in HER2-positive breast cancer.
Xiaoyu Chen, Ying Li, Zhiwei Zhou, Yanqiu Zhang, Luchen Chang, Kenneth D Westover

Cancer Med· October 2023

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LIMS-Kinase provides sensitive and generalizable label-free measurement of kinase activity using mass spectrometry.
Cynthia Meyer, Melissa McCoy, Lianbo Li, Bruce Posner, Kenneth D Westover

Cell Rep Phys Sci· October 2023

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Development of a Covalent Inhibitor of c-Jun N-Terminal Protein Kinase (JNK) 2/3 with Selectivity over JNK1.
Wenchao Lu, Yao Liu, Yang Gao, Qixiang Geng, Deepak Gurbani, Kenneth D Westover

J Med Chem· March 2023

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Synthesis and Structure-Activity relationships of cyclin-dependent kinase 11 inhibitors based on a diaminothiazole scaffold.
Zhengnian Li, Ryosuke Ishida, Yan Liu, Jinhua Wang, Yina Li, Kenneth D Westover

Eur J Med Chem· August 2022

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Case Report: Resolution of radiation pneumonitis with androgens and growth hormone.
Allen Yen, Kenneth D Westover

Front Oncol· August 2022

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Thermal Shift Assay for Small GTPase Stability Screening: Evaluation and Suitability.
Kari Kopra, Salla Valtonen, Randa Mahran, Jonas N Kapp, Nazia Hassan, Kenneth D Westover

Int J Mol Sci· June 2022

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T Stage and Pretreatment Standardized Uptake Values Predict Tumor Recurrence With 5-Fraction SABR in Early-Stage Non-Small Cell Lung Cancer.
Eric J Hsu, Jameson T Mendel, Kristin A Ward, Mariam El-Ashmawy, Minjae Lee, Kenneth D Westover

Adv Radiat Oncol· May 2022

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ADAP1 promotes latent HIV-1 reactivation by selectively tuning KRAS-ERK-AP-1 T cell signaling-transcriptional axis.
Nora-Guadalupe P Ramirez, Jeon Lee, Yue Zheng, Lianbo Li, Bryce Dennis, Kenneth D Westover

Nat Commun· March 2022

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PD-L1 is prognostic and a negative predictor of response to immunotherapy in gastric cancer.
Qing Li, Zhi-Wei Zhou, Jia Lu, Hao Luo, Shu-Nan Wang, Kenneth D Westover

Mol Ther· February 2022

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Acid-Catalyzed Synthesis of Isatoic Anhydride-8-Secondary Amides Enables IASA Transformations for Medicinal Chemistry.
Sudershan R Gondi, Althaf Shaik, Kenneth D Westover

J Org Chem· January 2022

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A structural model of a Ras-Raf signalosome.
Venkatesh P Mysore, Zhi-Wei Zhou, Chiara Ambrogio, Lianbo Li, Jonas N Kapp, Kenneth D Westover

Nat Struct Mol Biol· October 2021

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Lentiviral-Driven Discovery of Cancer Drug Resistance Mutations.
Paul Yenerall, Rahul K Kollipara, Kimberley Avila, Michael Peyton, Christopher A Eide, Kenneth D Westover

Cancer Res· September 2021

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Thirteen-Year Survival in a Patient With Diffuse Bilateral Lepidic-Predominant Adenocarcinoma: A Case Report of Lung Transplantation and Local Salvage.
Elizabeth R Zhang-Velten, David E Gerber, Kenneth D Westover

JTO Clin Res Rep· November 2020

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