Publications by authors named "Kenneth E Huffman"

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Induced degradation of lineage-specific oncoproteins drives the therapeutic vulnerability of small cell lung cancer to PARP inhibitors.
Chiho Kim, Xu-Dong Wang, Zhengshuai Liu, Jianwei Hao, Shuai Wang, Kenneth E Huffman

Sci Adv· January 2024

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Glucocorticoid mediated inhibition of LKB1 mutant non-small cell lung cancers.
Kenneth E Huffman, Long Shan Li, Ryan Carstens, Hyunsil Park, Luc Girard

Front Oncol· March 2023

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Evasion of Innate Immunity Contributes to Small Cell Lung Cancer Progression and Metastasis.
Mingrui Zhu, Yi Huang, Matthew E Bender, Luc Girard, Rahul Kollipara, Kenneth E Huffman

Cancer Res· April 2021

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Guanosine triphosphate links MYC-dependent metabolic and ribosome programs in small-cell lung cancer.
Fang Huang, Kenneth E Huffman, Zixi Wang, Xun Wang, Kailong Li

J Clin Invest· January 2021

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SCLC-CellMiner: A Resource for Small Cell Lung Cancer Cell Line Genomics and Pharmacology Based on Genomic Signatures.
Camille Tlemsani, Lorinc Pongor, Fathi Elloumi, Luc Girard, Kenneth E Huffman

Cell Rep· October 2020

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Subtype-specific secretomic characterization of pulmonary neuroendocrine tumor cells.
Xu-Dong Wang, Rongkuan Hu, Qing Ding, Trisha K Savage, Kenneth E Huffman

Nat Commun· July 2019

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Author Correction: CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells.
Jiyeon Kim, Zeping Hu, Ling Cai, Kailong Li, Eunhee Choi, Kenneth E Huffman

Nature· May 2019

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Inosine Monophosphate Dehydrogenase Dependence in a Subset of Small Cell Lung Cancers.
Fang Huang, Min Ni, Milind D Chalishazar, Kenneth E Huffman, Jiyeon Kim

Cell Metab· September 2018

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Quantitative Proteomic Analysis of Optimal Cutting Temperature (OCT) Embedded Core-Needle Biopsy of Lung Cancer.
Xiaozheng Zhao, Kenneth E Huffman, Junya Fujimoto, Jamie Rodriguez Canales, Luc Girard

J Am Soc Mass Spectrom· October 2017

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CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells.
Jiyeon Kim, Zeping Hu, Ling Cai, Kailong Li, Eunhee Choi, Kenneth E Huffman

Nature· June 2017

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Functional polyesters enable selective siRNA delivery to lung cancer over matched normal cells.
Yunfeng Yan, Li Liu, Hu Xiong, Jason B Miller, Kejin Zhou, Kenneth E Huffman

Proc Natl Acad Sci U S A· September 2016

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Fatty Acid Oxidation Mediated by Acyl-CoA Synthetase Long Chain 3 Is Required for Mutant KRAS Lung Tumorigenesis.
Mahesh S Padanad, Georgia Konstantinidou, Niranjan Venkateswaran, Margherita Melegari, Smita Rindhe, Kenneth E Huffman

Cell Rep· August 2016

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Erratum: NRF2 regulates serine biosynthesis in non-small cell lung cancer.
Gina M DeNicola, Pei-Hsuan Chen, Edouard Mullarky, Jessica A Sudderth, Zeping Hu, Kenneth E Huffman

Nat Genet· April 2016

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Quantitative Secretomic Analysis Identifies Extracellular Protein Factors That Modulate the Metastatic Phenotype of Non-Small Cell Lung Cancer.
Rongkuan Hu, Kenneth E Huffman, Michael Chu, Yajie Zhang, John D Minna

J Proteome Res· February 2016

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Cancer-Specific Production of N-Acetylaspartate via NAT8L Overexpression in Non-Small Cell Lung Cancer and Its Potential as a Circulating Biomarker.
Tzu-Fang Lou, Deepa Sethuraman, Patrick Dospoy, Pallevi Srivastva, Hyun Seok Kim, Kenneth E Huffman

Cancer Prev Res (Phila)· January 2016

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NRF2 regulates serine biosynthesis in non-small cell lung cancer.
Gina M DeNicola, Pei-Hsuan Chen, Edouard Mullarky, Jessica A Sudderth, Zeping Hu, Kenneth E Huffman

Nat Genet· December 2015

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A systematic analysis reveals heterogeneous changes in the endocytic activities of cancer cells.
Sarah R Elkin, Nawal Bendris, Carlos R Reis, Yunyun Zhou, Yang Xie, Kenneth E Huffman

Cancer Res· November 2015

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A Subset of Nuclear Receptors are Uniquely Expressed in Uveal Melanoma Cells.
Kenneth Edward Huffman, Ryan Carstens, Elisabeth D Martinez

Front Endocrinol (Lausanne)· July 2015

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Systematic siRNA Screen Unmasks NSCLC Growth Dependence by Palmitoyltransferase DHHC5.
Hui Tian, Jui-Yun Lu, Chunli Shao, Kenneth E Huffman, Ryan M Carstens

Mol Cancer Res· April 2015

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Inhibition of cancer cell proliferation by PPARγ is mediated by a metabolic switch that increases reactive oxygen species levels.
Nishi Srivastava, Rahul K Kollipara, Dinesh K Singh, Jessica Sudderth, Zeping Hu, Kenneth E Huffman

Cell Metab· October 2014

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Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer.
Charles M Rudin, Steffen Durinck, Eric W Stawiski, John T Poirier, Zora Modrusan, Kenneth E Huffman

Nat Genet· October 2012

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Activating gene expression in mammalian cells with promoter-targeted duplex RNAs.
Bethany A Janowski, Scott T Younger, Daniel B Hardy, Rosalyn Ram, Kenneth E Huffman

Nat Chem Biol· March 2007

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Involvement of AGO1 and AGO2 in mammalian transcriptional silencing.
Bethany A Janowski, Kenneth E Huffman, Jacob C Schwartz, Rosalyn Ram, Robert Nordsell

Nat Struct Mol Biol· September 2006

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Inhibiting transcription of chromosomal DNA with antigene peptide nucleic acids.
Bethany A Janowski, Kunihiro Kaihatsu, Kenneth E Huffman, Jacob C Schwartz, Rosalyn Ram

Nat Chem Biol· September 2005

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Inhibiting gene expression at transcription start sites in chromosomal DNA with antigene RNAs.
Bethany A Janowski, Kenneth E Huffman, Jacob C Schwartz, Rosalyn Ram, Daniel Hardy

Nat Chem Biol· September 2005

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